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10 Best Antibacterial Sprays 2025 in the United States

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Our Top Picks

#1

Winner

Lysol Disinfectant Spray, Household Essential Cleaning Supplies, Multi-Purpose Room Spray, Antibacterial Sanitizer Spray, Upholstery Deodorizer, Home and Bathroom, Crisp Linen,19 Fl Oz (Pack of 2)

Rating
10.0
Chosen by1,240
Scent
Ease of Use

Most important from
67885 reviews

Scent
This Lysol Disinfectant Spray works just as expected. It smells fresh and gets the job done.
Ease of Use
Lysol disinfectant spray has a great smell, easy to use. We were able to clean/disinfect quickly.

The Lysol Disinfectant Spray is a versatile product designed to sanitize and deodorize various surfaces in your home. It is effective against 99.9% of viruses and bacteria, including Covid-19, making it highly reliable for disinfecting your home environment. Its active ingredients work quickly, with proven efficacy against SARS-CoV-2 in 15 seconds and other viruses in 30 seconds, which is impressive for contact time.

This spray is suitable for both hard, non-porous surfaces and soft surfaces like upholstery, providing broad usability throughout your home. However, it's important to note that it should not be used on brass, copper, or aluminum surfaces and requires rinsing for food contact surfaces and plastic toys, which may add an extra step to your cleaning routine.

The crisp linen scent is pleasant. Its ease of use is evident with a simple spray mechanism, though the necessity for rinsing specific surfaces may slightly complicate usage. Ideal for households with pets and children due to its deodorizing properties, this spray can help maintain a fresh, clean environment.

Rating
10.0
Chosen by1,240
Scent
Ease of Use

Most important from
67885 reviews

Scent
This Lysol Disinfectant Spray works just as expected. It smells fresh and gets the job done.
Ease of Use
Lysol disinfectant spray has a great smell, easy to use. We were able to clean/disinfect quickly.
#2

Purell Professional Surface Disinfectant Spray, Citrus Scent, 32 fl oz Capped Bottle with Spray Trigger in Pack (Pack of 6) - 3342-06

Rating
9.7
Active Ingredients
Contact Time
Surface Compatibility

Most important from
1309 reviews

Active Ingredients
Delivers a genuine feeling of cleanliness without the harsh chemical smell typical of disinfectants.
Contact Time
Leaves no streaks or residue on surfaces when wiped after the recommended contact time.
Surface Compatibility
Highly effective across a wide range of surfaces, making it an essential staple for thorough sanitation.
Scent
The mild citrus scent is subtle enough to be barely noticeable, ideal for environments with children and pets.
Ease of Use
The sprayer mechanism is smooth and user-friendly, enhancing the overall convenience of use.

The PURELL Professional Surface Disinfectant Spray is a solid choice if you're looking for an effective antibacterial spray with a pleasant citrus scent that fades quickly. It kills 99.9% of common germs and viruses, including cold and flu-causing bugs and tough bacteria like MRSA and Listeria, which makes it suitable for both home and workplace use. One of its standout features is that it works on a wide range of surfaces, including soft ones and even food-contact areas, without needing to rinse afterward. This convenience is great if you want quick and easy sanitation.

The spray is certified by the EPA’s Design for the Environment program, meaning it avoids harsh chemicals, which reduces environmental impact and the need for protective measures like handwashing after use. The fast contact time helps get surfaces disinfected quickly, speeding up turnaround times in busy settings. However, this product comes in a case of six large 32-ounce bottles, which might be bulky or more than needed for casual users or small households. Also, while the citrus scent is mild, some people may prefer a fragrance-free option.

This disinfectant spray is well suited for users needing a reliable, fast-acting, and environmentally considerate antibacterial solution for various surfaces, especially in offices, schools, or food service environments.

Rating
9.7
Active Ingredients
Contact Time
Surface Compatibility

Most important from
1309 reviews

Active Ingredients
Delivers a genuine feeling of cleanliness without the harsh chemical smell typical of disinfectants.
Contact Time
Leaves no streaks or residue on surfaces when wiped after the recommended contact time.
Surface Compatibility
Highly effective across a wide range of surfaces, making it an essential staple for thorough sanitation.
Scent
The mild citrus scent is subtle enough to be barely noticeable, ideal for environments with children and pets.
Ease of Use
The sprayer mechanism is smooth and user-friendly, enhancing the overall convenience of use.
#3

LYSOL All-Purpose Cleaner, Sanitizing and Disinfecting Spray, To Clean and Deodorize, Lemon Breeze Scent, 32oz, Pack of 2

Rating
9.1
Active Ingredients
Surface Compatibility
Scent

Most important from
30530 reviews

Active Ingredients
Kills 99.9% of germs, including the dreaded COVID-19 virus, making users feel like they are doing their part to save the world.
Surface Compatibility
Strong enough to tackle grease and grime but gentle enough to use on different types of surfaces without causing any damage.
Scent
The lemon breeze scent is refreshing and not overpowering, leaving my home smelling clean without any harsh chemical odors.
Ease of Use
The Lysol All-Purpose Cleaner not only sanitizes and disinfects but also cuts through grease and grime with ease.

Lysol All-Purpose Cleaner is a versatile antibacterial spray designed to kill 99.9% of viruses and bacteria, including the COVID-19 virus. It achieves this with a contact time of just 2 minutes on hard, non-porous surfaces, making it quick and effective. The spray is suitable for various surfaces throughout your home, such as kitchens and bathrooms, and it not only disinfects but also removes soap scum and tough grease, ensuring a deep clean.

Users will appreciate the fresh lemon breeze scent, which helps to deodorize spaces after cleaning, leaving a pleasant smell. However, for those sensitive to scents, this might be a drawback as the lemon fragrance is quite noticeable. The cleaner is easy to use, thanks to its liquid form and spray mechanism, which simplifies application.

The cleaner's versatility and effectiveness make it a strong choice for households needing a reliable disinfectant and deodorizer.

Rating
9.1
Active Ingredients
Surface Compatibility
Scent

Most important from
30530 reviews

Active Ingredients
Kills 99.9% of germs, including the dreaded COVID-19 virus, making users feel like they are doing their part to save the world.
Surface Compatibility
Strong enough to tackle grease and grime but gentle enough to use on different types of surfaces without causing any damage.
Scent
The lemon breeze scent is refreshing and not overpowering, leaving my home smelling clean without any harsh chemical odors.
Ease of Use
The Lysol All-Purpose Cleaner not only sanitizes and disinfects but also cuts through grease and grime with ease.

Buying Guide for the Best Antibacterial Sprays

Choosing the right antibacterial spray can be crucial for maintaining a clean and healthy environment. Whether you are looking to disinfect your home, office, or any other space, understanding the key specifications of antibacterial sprays will help you make an informed decision. Here are some important factors to consider when selecting an antibacterial spray.
Active IngredientsActive ingredients are the chemicals in the spray that kill bacteria and other pathogens. Common active ingredients include alcohol, hydrogen peroxide, and quaternary ammonium compounds. The effectiveness of the spray largely depends on these ingredients. For general household use, sprays with alcohol or hydrogen peroxide are often sufficient. For more heavy-duty disinfection, such as in medical settings, quaternary ammonium compounds may be more appropriate. Consider the type of bacteria or viruses you are targeting and choose a spray with active ingredients known to be effective against them.
Contact TimeContact time refers to the amount of time the spray needs to remain on a surface to effectively kill bacteria and viruses. This can range from a few seconds to several minutes. Shorter contact times are more convenient for quick clean-ups, while longer contact times may be necessary for thorough disinfection. If you need a spray for quick, everyday use, look for one with a shorter contact time. For deep cleaning, a longer contact time may be more effective.
Surface CompatibilityNot all antibacterial sprays are suitable for all surfaces. Some sprays can damage certain materials like wood, fabric, or electronics. It's important to check the label to ensure the spray is safe for the surfaces you intend to use it on. If you need a versatile spray for various surfaces, look for one labeled as multi-surface. For specific materials, choose a spray that is designed to be safe for those surfaces.
ScentThe scent of an antibacterial spray can affect your comfort and satisfaction with the product. Some sprays have strong chemical odors, while others are scented with fragrances like lemon or lavender. If you are sensitive to strong smells or prefer a pleasant fragrance, look for sprays that are labeled as having a mild or pleasant scent. Unscented options are also available for those who prefer no added fragrance.
Environmental ImpactThe environmental impact of antibacterial sprays is an important consideration for many people. Some sprays contain harsh chemicals that can be harmful to the environment. Eco-friendly options are available that use biodegradable ingredients and are free from harmful chemicals. If environmental sustainability is important to you, look for sprays that are labeled as eco-friendly or biodegradable.
Ease of UseEase of use refers to how convenient and user-friendly the spray is. This includes factors like the design of the spray bottle, how easy it is to apply, and whether it leaves any residue. A well-designed spray bottle with an ergonomic trigger can make the application process more comfortable. If you need a spray for frequent use, consider one that is easy to handle and does not leave a sticky or greasy residue.

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