10 Best Broadleaf Herbicides 2025 in the United States

The Dow AgroSciences Milestone Specialty Herbicide is designed to tackle noxious and invasive weeds, making it a strong choice for those dealing with tough, unwanted vegetation. The active ingredient, Aminopyralid, is highly effective in targeting broadleaf weeds while sparing grasses and other non-target plants, which makes it a selective herbicide. This specificity is useful for maintaining the health of desirable plants in treated areas.

It comes in a liquid form and a sizable 2.5-gallon volume, which can cover approximately one acre per gallon, making it suitable for large-scale applications such as fields, pastures, and rights-of-way. The application method is typically straightforward, involving dilution and spraying, which can be managed with common agricultural equipment. One of the notable strengths is its residual control, meaning it continues to prevent weed growth long after application, reducing the need for frequent treatments.

Additionally, it is rainfast, meaning it won't wash away easily in the rain, ensuring its efficacy even in variable weather conditions. However, like many chemical herbicides, there are environmental considerations. While it is designed to be safe for grasslands and non-target plants, care must be taken to avoid contamination of water sources and unintended exposure to non-target species. Users should follow safety guidelines closely to mitigate any negative environmental impacts. In summary, Dow AgroSciences Milestone Specialty Herbicide offers strong, targeted control of invasive weeds with long-lasting effects, although users must handle it responsibly to ensure safety for the environment and non-target plants.

The Agrisel Pendi Hydrocap Weed Killer is a pre-emergent herbicide designed to tackle over 40 types of broadleaf weeds and grasses. Using active ingredients that stop weed seeds just as they germinate, this product is particularly effective against common weeds like crabgrass, chickweed, and spurge. Its water-based, no-stain formula is user-friendly and minimizes odors, making it easy to mix with other lawn treatments.

The product is also endorsed by the EPA, ensuring it meets safety standards for home and ornamental use. It offers good residual control, as a single application can cover a substantial area of up to 1,000 square feet with just 1.1 to 2.3 ounces, making it an economical choice for large gardens or lawns. The herbicide is rainfast, meaning it quickly becomes resistant to being washed away by rain, which is a significant advantage for those in unpredictable climates. Additionally, the product is pet safe, reducing concerns for households with animals.

However, it is crucial to note that the weed sprayer is sold separately, which may be an additional cost to consider. While the product offers multiple size options, its 320-ounce size might be unwieldy for smaller gardens. This product is best suited for those looking to maintain large areas free of broadleaf weeds with minimal fuss.

Garlon 4 Ultra is a liquid herbicide featuring triclopyr as its active ingredient, targeting a wide range of woody plants, broadleaf weeds, and brush. It's designed primarily for outdoor use in areas such as fence rows, rights-of-way, railroads, and roadsides, making it a strong choice for controlling tough brush and unwanted trees like box elder, buckthorn, locust, and sumac. Because it is applied as a spray, it offers straightforward use for those familiar with garden or landscaping treatments.

This selective herbicide focuses on broadleaf plants while leaving grasses mostly unaffected, which helps protect lawns and gardens. It is important to follow safety guidelines closely to minimize any impact on nearby plants during application. Additionally, the product cannot be shipped to some states including Alaska, California, Hawaii, and New York, which may limit its availability depending on your location.

For managing woody brush and broadleaf weeds in non-residential or utility areas, Garlon 4 Ultra provides effective control. Users should also check local regulations before use to ensure compliance.