10 Best Broadleaf Herbicides 2025 in the United States

The Southern Ag Amine 2,4-D Weed Killer comes in a 32-ounce (quart) bottle and is designed to control a wide range of broadleaf weeds and woody plants. It can be used in various settings including turf, pastures, rangeland, ditch banks, and along fences. With an economical use rate of 1 to 4 pints per acre, it offers good value for large-scale applications, covering up to 5000 square feet per unit.

The active ingredient, Ag Amine, is selective, meaning it targets specific types of weeds without damaging grass, making it ideal for lawns and other grassy areas. Being a chemical herbicide, it is important to consider its safety and environmental impact. The product should be used carefully to avoid harming non-target plants and wildlife. It is also rainfast, meaning it won’t wash away easily after application, which enhances its reliability.

Although it’s not the most environmentally friendly option available, it is a powerful and economical choice for those needing effective weed control.

The Agrisel Pendi Hydrocap Weed Killer is a pre-emergent herbicide designed to tackle over 40 types of broadleaf weeds and grasses. Using active ingredients that stop weed seeds just as they germinate, this product is particularly effective against common weeds like crabgrass, chickweed, and spurge. Its water-based, no-stain formula is user-friendly and minimizes odors, making it easy to mix with other lawn treatments.

The product is also endorsed by the EPA, ensuring it meets safety standards for home and ornamental use. It offers good residual control, as a single application can cover a substantial area of up to 1,000 square feet with just 1.1 to 2.3 ounces, making it an economical choice for large gardens or lawns. The herbicide is rainfast, meaning it quickly becomes resistant to being washed away by rain, which is a significant advantage for those in unpredictable climates. Additionally, the product is pet safe, reducing concerns for households with animals.

However, it is crucial to note that the weed sprayer is sold separately, which may be an additional cost to consider. While the product offers multiple size options, its 320-ounce size might be unwieldy for smaller gardens. This product is best suited for those looking to maintain large areas free of broadleaf weeds with minimal fuss.

Garlon 4 Ultra is a liquid herbicide featuring triclopyr as its active ingredient, targeting a wide range of woody plants, broadleaf weeds, and brush. It's designed primarily for outdoor use in areas such as fence rows, rights-of-way, railroads, and roadsides, making it a strong choice for controlling tough brush and unwanted trees like box elder, buckthorn, locust, and sumac. Because it is applied as a spray, it offers straightforward use for those familiar with garden or landscaping treatments.

This selective herbicide focuses on broadleaf plants while leaving grasses mostly unaffected, which helps protect lawns and gardens. It is important to follow safety guidelines closely to minimize any impact on nearby plants during application. Additionally, the product cannot be shipped to some states including Alaska, California, Hawaii, and New York, which may limit its availability depending on your location.

For managing woody brush and broadleaf weeds in non-residential or utility areas, Garlon 4 Ultra provides effective control. Users should also check local regulations before use to ensure compliance.