10 Best Disinfectant Sprays 2025 in the United States

Lysol Disinfectant Spray in Crisp Linen scent is a versatile cleaning product designed for household use. It boasts an ability to kill 99.9% of viruses and bacteria, including the Covid-19 virus, making it a reliable choice for maintaining hygiene. This spray can be applied to both hard and soft surfaces, from countertops and bathroom fixtures to upholstery and toys.

However, it’s important to note that it is not recommended for use on brass, copper, or aluminum surfaces and requires rinsing on food contact surfaces and plastic toys after use, which could be a minor inconvenience for some users. The product is scented, leaving a fresh linen fragrance that replaces odors, which can be appealing in homes with pets and children. The EPA registration provides assurance of the product’s effectiveness and safety when used as directed.

The contact time for disinfection varies, with some viruses being killed in as little as 15 seconds, while others might take longer. It is a practical option for anyone looking to keep their living space sanitized and smelling fresh, but users should consider the scent preference and material restrictions before purchasing.

Purell Healthcare Surface Disinfectant is a fragrance-free, gallon-sized disinfectant designed for healthcare and similar environments where cleanliness is crucial. It effectively kills 99.9% of viruses and bacteria, including tough ones like norovirus, MRSA, and the COVID-19 virus, making it reliable for infection control. It works on a wide range of surfaces — from hard ones like tables and counters to softer items like privacy curtains and upholstered furniture, which adds versatility.

One of its main benefits is that it has no harsh fumes, so it’s safer and more comfortable for staff and patients to use, and you don’t need to wash your hands immediately after applying it. This product is EPA registered and certified for environmental safety, which is important for those concerned about chemical impact. The disinfectant also claims to have the fastest disinfection times among similar environmentally certified products, helping to speed up cleaning routines. The large gallon refill size is convenient for busy settings but might be less handy for casual or home use due to its bulk and weight.

Purell Healthcare Surface Disinfectant represents a strong choice for healthcare or commercial spaces needing a versatile, effective, and low-odor disinfectant, though it may be less practical for everyday household use or users seeking more detailed ingredient information.

Lysol Disinfectant Spray in Early Morning Breeze scent is a versatile and powerful household disinfectant. It is designed to kill 99.9% of viruses and bacteria, including the Covid-19 virus, which makes it incredibly effective for maintaining a hygienic environment. The spray can be used on a wide range of surfaces, both hard and soft, which includes counters, kids' toys, couches, and bathrooms, offering great flexibility.

It is also an effective deodorizer, capable of eliminating tough odors and leaving a fresh floral scent, suitable for households with pets and children. However, users should be mindful that some surfaces like brass, copper, and aluminum are not recommended for use with this product, which can limit its application in certain areas. Additionally, the spray requires a contact time of 30 seconds for some viruses and 15 seconds for the Covid-19 virus, which is relatively quick and convenient.

Users need to rinse food contact surfaces and plastic toys with water after use, which adds an extra step to the cleaning process. The product is EPA registered, ensuring its compliance with safety and health standards. The Lysol Disinfectant Spray excels in killing germs and deodorizing spaces effectively, and the packaging may vary, which could be a minor inconvenience for some users. It is a reliable choice for anyone looking to sanitize and freshen up their living spaces, provided they follow the usage instructions carefully.