10 Best Dog Urine Cleaners 2025 in the United States

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator is a strong choice if you're dealing with pet urine stains and odors. It uses an enzymatic formula that breaks down organic stains like urine, feces, and vomit, helping eliminate both visible stains and lingering smells. This cleaner is safe for a wide range of surfaces including carpets, floors, furniture, and even pet bedding, making it versatile for various household spots where accidents happen.

The product is certified safe by the Carpet and Rug Institute, chlorine-free, and contains no harsh chemicals, so it’s gentle around pets and children. The scent is described as original, suggesting it’s not heavily perfumed, which is beneficial for those who prefer mild-smelling cleaners. Usage is straightforward: shake, pre-test on a hidden spot, and apply, though care is needed to avoid color fading.

It comes in a large 1-gallon size, which is convenient for heavy users but might be bulky for smaller households. Customer reviews are mostly positive, highlighting its effectiveness, although some users mention that stubborn stains may require multiple applications. This product suits pet owners looking for a natural, powerful solution to keep their home fresh without worrying about harmful chemicals.

The Rocco & Roxie Extreme Stain & Odor Eliminator is a solid choice if you're looking for an enzymatic cleaner to tackle tough pet messes like dog urine, vomit, and other organic stains. Its enzymatic formula is enhanced with a mineral-based neutralizer that works deep into the stain to break down ammonia crystals and organic residues, which is key for stopping odors at the source rather than just masking them. This product is versatile and safe to use on many surfaces including carpets, floors, furniture, pet bedding, and car interiors, making it handy for various accident spots around your home or vehicle. The light Meyer lemon scent is subtle and fades quickly, so it won’t leave an overpowering smell behind. Safety is another strong point here since it’s chlorine-free, color-safe, and certified by the Carpet and Rug Institute, meaning it won’t damage carpet fibers and is safe around pets and children when used as directed. Users also find it straightforward to use as a spray liquid with good coverage.

Some extremely old or heavy buildup might require repeated application, which is fairly common with enzymatic cleaners. The price might be a bit higher compared to basic cleaners, but many find it worth the investment due to its performance and safety profile. For pet owners dealing with regular accidents who want a reliable, safe, and versatile enzymatic cleaner that works well on multiple surfaces and leaves a fresh but mild scent, this product fits those needs well.

The ANGRY ORANGE Pet Odor Eliminator for Dog Urine and Smells is a versatile cleaner designed to tackle strong pet odors. One of its major strengths is its powerful odor-fighting capabilities, targeting and eliminating lingering smells at the source. This product stands out because it is multipurpose; it can be used on various surfaces like carpets, tiles, couch upholstery, garbage cans, car interiors, and even turf, making it suitable for many households with pets.

The citrus scent, derived from fresh orange peels, not only masks the odor but leaves a pleasant smell behind, which many users might find appealing. However, it’s worth noting that the product is not enzymatic, which means it might not break down urine stains as effectively as some enzymatic cleaners would. This can be a drawback for those specifically looking for a solution to remove both the odor and the stain thoroughly.

Safety-wise, the cleaner requires pets to be removed from the area during application, which is fairly standard but still an important consideration for pet owners. The ease of use is enhanced by the product being a spray, which simplifies the application process. The gallon size serves as a refill for smaller bottles, making it cost-effective in the long run. This product is particularly good for those who need a strong, citrus-scented cleaner for various surfaces and are looking for a long-term, cost-effective solution to manage pet odors rather than removing stains.