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10 Best Enzymatic Cleaners For Cat Urine 2025 in the United States

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Our Top Picks

#1

Winner

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

Rating
10.0
Chosen by1,404
Application Method
Surface Compatibility
Odor Control

Most important from
28486 reviews

Application Method
Easy to use with straightforward instructions, just spray and wipe away, no need for dilution.
Surface Compatibility
Versatile application on various surfaces like carpets, floors, fabric, and upholstery makes it a practical choice for many cleaning needs.
Odor Control
The citrus scent is a refreshing change from typical cleaners and helps eliminate pet odors effectively.

The Angry Orange Stain Remover is a versatile enzymatic cleaner designed to tackle pet stains and odors effectively. Its powerful 2-in-1 enzyme formula not only breaks down pet urine, feces, and vomit but also eliminates the odor, rather than merely masking it. This makes it particularly useful for pet owners dealing with persistent stains and smells.

The cleaner is multipurpose, suitable for a wide range of surfaces including carpets, tiles, hardwood, upholstery, and even car interiors, which adds to its practicality. With easy application instructions, users can simply clean the excess mess, spray the solution, and let the enzymes work their magic. The fresh citrus scent left behind is a pleasant bonus for households looking to maintain a clean and fresh environment.

The 32oz bottle is a decent size for multiple uses, and the responsive customer service provides additional reassurance for any issues. This cleaner is a solid choice for pet owners needing a reliable method to combat tough stains and odors.

Rating
10.0
Chosen by1,404
Application Method
Surface Compatibility
Odor Control

Most important from
28486 reviews

Application Method
Easy to use with straightforward instructions, just spray and wipe away, no need for dilution.
Surface Compatibility
Versatile application on various surfaces like carpets, floors, fabric, and upholstery makes it a practical choice for many cleaning needs.
Odor Control
The citrus scent is a refreshing change from typical cleaners and helps eliminate pet odors effectively.
#2

Angry Orange Pet Stain Remover for Cat Urine and Stains - Enzyme Cleaner - Fresh Scent - 32 oz

Rating
10.0
Application Method
Surface Compatibility
Odor Control

Most important from
28487 reviews

Application Method
Using a generous amount of the cleaner can make a significant difference in odor removal.
Surface Compatibility
It's versatile and works well on various surfaces, including carpets and pet play pens.
Odor Control
This cleaner is a lifesaver for those struggling with persistent cat urine odors.

Angry Orange Pet Stain Remover is a dual-action enzymatic cleaner designed to tackle both stains and odors caused by cat urine, feces, and vomit. The enzyme type used is effective in breaking down organic matter, making it suitable for a variety of messes. Application is simple: shake well, spray on the affected area, and allow the enzymes to work.

This cleaner is highly versatile, compatible with multiple surfaces including carpet, tile, hardwood, upholstery, and even car interiors, making it a practical choice for various cleaning needs. The fresh linen scent is a pleasant bonus, as it eliminates odors rather than merely masking them.

Another strong point is its eco-friendliness, indicated by the natural material feature. Some users might find the 32 oz size insufficient for extensive cleaning tasks. Nevertheless, the responsive customer service is a plus for any issues that might arise. This enzymatic cleaner is ideal for pet owners looking for a reliable and versatile solution to cat urine and other pet-related stains and odors.

Rating
10.0
Application Method
Surface Compatibility
Odor Control

Most important from
28487 reviews

Application Method
Using a generous amount of the cleaner can make a significant difference in odor removal.
Surface Compatibility
It's versatile and works well on various surfaces, including carpets and pet play pens.
Odor Control
This cleaner is a lifesaver for those struggling with persistent cat urine odors.
#3

Simple Solution Extreme Pet Stain and Odor Remover | Enzymatic Cleaner with 3X Pro-Bacteria Cleaning Power | 1 Gallon , 128 Fl Oz (Pack of 1)

Rating
9.7
Enzyme Type
Application Method
Surface Compatibility

Most important from
36414 reviews

Enzyme Type
The product prevents pets from returning to the same spot to pee, thanks to its strong enzyme formula.
Application Method
The solution sprays well with three different spray settings, making it versatile for various cleaning needs.
Surface Compatibility
Safe for use on multiple surfaces, it’s a reliable cleaner for homes with both pets and children.
Odor Control
The multipurpose spray is highly effective, with a pleasant, light powder scent that doesn't overpower.

The Simple Solution Extreme Pet Stain and Odor Remover is designed to be highly effective at dealing with pet messes, specifically cat urine. It boasts a formula that is three times stronger than its regular version, employing Pro-Bacteria and enzymes to break down and eliminate tough stains and odors. This can be particularly beneficial for households with pets prone to accidents, ensuring that odors and stains are thoroughly removed to discourage repeat marking.

The product is versatile in its application, being safe for use on a variety of water-safe surfaces including carpets, upholstery, bedding, fabric toys, and clothing. This broad surface compatibility means it can be a go-to cleaner for various areas in your home. Additionally, it is designed to be safe for both children and pets when used as directed, making it a family-friendly option for pet owners.

Despite these minor drawbacks, the Simple Solution Extreme Pet Stain and Odor Remover stands out as a potent and versatile cleaner that can effectively manage cat urine and other pet messes.

Rating
9.7
Enzyme Type
Application Method
Surface Compatibility

Most important from
36414 reviews

Enzyme Type
The product prevents pets from returning to the same spot to pee, thanks to its strong enzyme formula.
Application Method
The solution sprays well with three different spray settings, making it versatile for various cleaning needs.
Surface Compatibility
Safe for use on multiple surfaces, it’s a reliable cleaner for homes with both pets and children.
Odor Control
The multipurpose spray is highly effective, with a pleasant, light powder scent that doesn't overpower.

Buying Guide for the Best Enzymatic Cleaners For Cat Urine

Choosing the right enzymatic cleaner for cat urine can make a significant difference in maintaining a clean and odor-free home. Enzymatic cleaners are specifically designed to break down the proteins in cat urine, eliminating both the stain and the odor. When selecting an enzymatic cleaner, it's important to consider several key specifications to ensure you get the best product for your needs. Understanding these specifications will help you make an informed decision and keep your home fresh and clean.
Enzyme TypeEnzyme type refers to the specific enzymes used in the cleaner to break down the urine. This is important because different enzymes target different components of the urine. Common enzymes include proteases, which break down proteins, and amylases, which break down starches. For cat urine, proteases are particularly effective. When choosing a cleaner, look for one that specifically mentions it targets pet urine or cat urine to ensure it contains the right enzymes.
Application MethodThe application method refers to how the cleaner is applied to the affected area. This can include spray bottles, pour bottles, or even powders. The method is important because it affects how easy and effective the cleaner is to use. Spray bottles are convenient for small spots and quick applications, while pour bottles might be better for larger areas or deep cleaning. Consider the size of the area you need to clean and how frequently you will use the product to determine the best application method for you.
Surface CompatibilitySurface compatibility indicates which surfaces the cleaner can be safely used on, such as carpets, hardwood floors, upholstery, or tile. This is crucial because using the wrong cleaner on a surface can cause damage. Check the product label to ensure it is safe for the surfaces you need to clean. If you have multiple types of surfaces, look for a versatile cleaner that works on various materials.
Odor ControlOdor control refers to the cleaner's ability to eliminate or neutralize odors, rather than just masking them. This is important for ensuring that the smell of cat urine is completely removed from your home. Some cleaners also include additional ingredients to leave a pleasant scent. If you are sensitive to fragrances or prefer a neutral smell, choose a product that focuses on odor elimination without added scents.
Drying TimeDrying time is the amount of time it takes for the cleaner to dry after application. This is important because it affects how quickly you can use the cleaned area again. Fast-drying cleaners are convenient for busy households, while slower-drying options might be more thorough in breaking down stains and odors. Consider your schedule and how quickly you need the area to be usable when choosing a cleaner.
Eco-FriendlinessEco-friendliness refers to the environmental impact of the cleaner, including the ingredients used and the packaging. This is important for those who are environmentally conscious and want to reduce their ecological footprint. Look for cleaners that are biodegradable, non-toxic, and come in recyclable packaging. If sustainability is a priority for you, choose a product that aligns with your values.

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