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10 Best Enzymatic Dog Toothpastes 2025 in the United States

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Our Top Picks

#1

Winner

FlyDog Fresh Kiss Dog Tooth Brushing Kit - Vet Approved Formula, Enzymatic Dog Toothpaste and Brush - Breath Freshener & Tartar Remover, 360° Toothbrush & Finger Brush, Dental Guide, Mint Flavor

Rating
10.0
Chosen by1,304
Flavor
Safety and Ingredients
Texture and Consistency

Most important from
35 reviews

Flavor
Some dogs may reject certain flavors despite liking the scent, so experimenting with flavors is worthwhile.
Safety and Ingredients
Natural ingredients and absence of artificial sweeteners contribute to a safe daily-use formula.
Texture and Consistency
The finger brush is a standout tool, offering gentle and effective cleaning that dogs tolerate well.
Packaging and Ease of Use
A thoughtful 4-week introduction guide makes it easy and enjoyable to build a consistent brushing routine.
Veterinary Recommendations
The included dental guide and brushing calendar are valuable for new pet owners to establish oral care habits.

The FlyDog Fresh Kiss Dog Tooth Brushing Kit is a solid choice if you want a vet-approved enzymatic toothpaste for your dog. It uses natural ingredients like coconut oil and enzymes that gently clean teeth and soothe gums without causing harm, which is important for daily use. The addition of vitamins C and B is a nice bonus, helping to prevent tartar buildup and supporting gum health. The mild mint flavor is designed to be pleasant for dogs, which can make brushing time easier and less stressful for both pet and owner.

This toothpaste is aluminum-free and made with organic components, enhancing its safety profile. The texture as a paste is standard and should spread easily on the brush. Speaking of brushes, the kit includes a 360° toothbrush and a finger brush, which allow you to reach different parts of your dog's mouth more effectively. Plus, the included dental guide and brushing calendar are helpful tools to build a consistent oral care routine, especially for new pet owners.

Some dogs might prefer other flavors, and although the kit is versatile, it may not suit dogs that strongly resist brushing. The packaging is compact and user-friendly, making storage and handling simple. If you're looking for a daily-use enzymatic toothpaste with thoughtful extras and vet backing, this kit covers most bases well without any glaring downsides.

Rating
10.0
Chosen by1,304
Flavor
Safety and Ingredients
Texture and Consistency

Most important from
35 reviews

Flavor
Some dogs may reject certain flavors despite liking the scent, so experimenting with flavors is worthwhile.
Safety and Ingredients
Natural ingredients and absence of artificial sweeteners contribute to a safe daily-use formula.
Texture and Consistency
The finger brush is a standout tool, offering gentle and effective cleaning that dogs tolerate well.
Packaging and Ease of Use
A thoughtful 4-week introduction guide makes it easy and enjoyable to build a consistent brushing routine.
Veterinary Recommendations
The included dental guide and brushing calendar are valuable for new pet owners to establish oral care habits.
#2

Virbac C.E.T. Oral Hygiene Kit for Cats and Dogs | 3 Piece Set with Dual Ended Toothbrush, Fingerbrush, and Poultry Flavor 2.5 oz tube of Toothpaste | Remove Plaque & Tartar Buildup

Rating
10.0
Flavor
Veterinary Recommendations

Most important from
5912 reviews

Flavor
The poultry flavor is loved by pets, enhancing the overall brushing experience.
Veterinary Recommendations
Vet recommendations highlight the effectiveness of this product, making it a worthy investment despite being slightly pricey.

The Virbac C.E.T. Oral Hygiene Kit for Cats and Dogs offers a comprehensive solution for pet dental care. The kit includes a dual-ended toothbrush, a fingerbrush, and a poultry-flavored toothpaste, designed to remove plaque and tartar buildup. The enzyme content in the toothpaste aids in breaking down plaque, which is essential for maintaining your pet's oral health. The poultry flavor is appealing to pets, making the brushing process more enjoyable for them. In terms of safety and ingredients, the toothpaste is formulated to be safe for both cats and dogs, with no harmful chemicals.

It has a medium firmness, which makes it suitable for regular use without being too abrasive on your pet's teeth and gums. The texture and consistency of the toothpaste are smooth, ensuring it spreads easily during brushing. The packaging is practical, with a long handle toothbrush that has a reverse angle for better reach and soft bristles that are gentle on your pet's mouth. The fingerbrush is an added convenience for more control while brushing smaller areas.

One drawback could be that the poultry flavor might not be suitable for pets with specific dietary restrictions or allergies. Additionally, while the kit is ergonomic and manually operated, it does require the pet owner to be consistent and patient with the brushing routine. Veterinary recommendations for this product are generally positive, emphasizing its effectiveness in maintaining oral hygiene. This kit is ideal for pet owners looking for a complete and user-friendly dental care solution for their cats and dogs.

Rating
10.0
Flavor
Veterinary Recommendations

Most important from
5912 reviews

Flavor
The poultry flavor is loved by pets, enhancing the overall brushing experience.
Veterinary Recommendations
Vet recommendations highlight the effectiveness of this product, making it a worthy investment despite being slightly pricey.
#3

Arm & Hammer for Pets Tartar Control Kit for Dogs Contains Toothpaste, Toothbrush & Fingerbrush Reduces Plaque & Tartar Buildup, 3-Piece Kit, Banana Mint Flavor (Pack of 1)

Rating
9.7
Flavor
Safety and Ingredients
Packaging and Ease of Use

Most important from
44266 reviews

Flavor
The banana mint flavor is pleasantly mild, encouraging dogs to enjoy the brushing experience without resistance.
Safety and Ingredients
The toothpaste’s gentle formula and appealing scent support stress-free brushing even for dogs new to dental care.
Packaging and Ease of Use
The toothbrush design, featuring multiple brush sizes on one tool, makes reaching back teeth simple and effective.

The Arm & Hammer for Pets Tartar Control Kit offers a convenient 3-piece set including toothpaste, toothbrush, and finger brush, designed to reduce plaque and tartar buildup while promoting healthier gums and fresher breath. Its toothpaste contains natural ingredients and baking soda, which helps gently clean teeth and brighten them without harsh chemicals, making it safe for dogs of all ages and sizes. The banana mint flavor is mild and generally appealing, which can help if your dog is hesitant about brushing.

A nice feature is the kit’s simple guidance for beginners, encouraging a gradual introduction to brushing, which makes it easier to establish a dental routine. In terms of texture and consistency, the toothpaste is designed to be easy to apply both directly on brush tools or a finger, offering flexibility according to your dog’s comfort level. Packaging is compact and straightforward, but it might not include a protective cap that some users prefer for freshness.

This kit suits pet owners looking for a gentle, easy-to-use dental care solution with familiar, safe ingredients, especially if your dog enjoys flavored toothpaste. For those seeking a product with stronger enzymatic action or explicit veterinary backing, other options may be preferable.

Rating
9.7
Flavor
Safety and Ingredients
Packaging and Ease of Use

Most important from
44266 reviews

Flavor
The banana mint flavor is pleasantly mild, encouraging dogs to enjoy the brushing experience without resistance.
Safety and Ingredients
The toothpaste’s gentle formula and appealing scent support stress-free brushing even for dogs new to dental care.
Packaging and Ease of Use
The toothbrush design, featuring multiple brush sizes on one tool, makes reaching back teeth simple and effective.

Buying Guide for the Best Enzymatic Dog Toothpastes

Choosing the right enzymatic dog toothpaste is essential for maintaining your dog's oral health. Enzymatic toothpastes contain enzymes that help break down plaque and tartar, making it easier to keep your dog's teeth clean and gums healthy. When selecting a toothpaste, consider your dog's specific needs and preferences to ensure you pick the best product for them.
Enzyme ContentEnzyme content is crucial because it determines the toothpaste's effectiveness in breaking down plaque and tartar. Enzymes like glucose oxidase and lactoperoxidase are commonly used. Higher enzyme content generally means better cleaning power. If your dog has significant plaque buildup, opt for a toothpaste with a higher enzyme concentration. For regular maintenance, a moderate enzyme content should suffice.
FlavorFlavor is important because it can make brushing a more pleasant experience for your dog. Common flavors include poultry, beef, and mint. Dogs have different taste preferences, so you may need to try a few flavors to see which one your dog likes best. If your dog is picky, choosing a flavor they enjoy can make the brushing process easier and more effective.
Safety and IngredientsSafety and ingredients are critical since dogs will ingest some of the toothpaste during brushing. Look for products that are free from harmful chemicals, artificial sweeteners like xylitol, and other toxic ingredients. Natural and organic options are often safer. If your dog has allergies or sensitivities, check the ingredient list carefully to avoid any adverse reactions.
Texture and ConsistencyTexture and consistency affect how easy the toothpaste is to apply and how well it stays on the brush. A thicker consistency can be easier to manage and less messy. If your dog is new to brushing, a paste that adheres well to the brush can make the process smoother. For experienced brushers, the texture may be less of a concern.
Packaging and Ease of UsePackaging and ease of use can influence how convenient the toothpaste is to use regularly. Tubes with easy-to-open caps and squeezable designs are generally more user-friendly. Some toothpastes come with applicator tips or brushes, which can be helpful if you don't already have a dog toothbrush. Choose packaging that fits your routine and makes the brushing process as hassle-free as possible.
Veterinary RecommendationsVeterinary recommendations can provide assurance of the product's effectiveness and safety. Toothpastes that are recommended or approved by veterinarians are often tested for quality and efficacy. If you're unsure which product to choose, consult your vet for advice tailored to your dog's specific dental health needs.

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