10 Best Enzymatic Dog Toothpastes 2025 in the United States

Vet’s Best Enzymatic Dog Toothpaste is a specialized dental care product designed for dogs. It is formulated by veterinarians and contains a mix of enzymes, aloe, neem oil, grapefruit seed extract, and baking soda. These ingredients help in effectively cleaning teeth, removing plaque and tartar, and freshening breath. The soothing properties of aloe and neem oil are a plus for dogs with sensitive gums.

One notable feature is its banana flavor which many dogs seem to enjoy, making the tooth brushing experience more pleasant for them. Additionally, it is free from parabens, enhancing its safety profile for pets. The toothpaste comes in a gel form which is easy to apply either with a brush or directly with fingers. The updated packaging in a squeeze tube adds to the convenience of use.

However, some pet owners may find the requirement to avoid food and water 30 minutes before and after application a bit inconvenient. Another minor drawback is that the product needs to be used 2–3 times per week for optimal results, which requires a bit of commitment. Despite these minor inconveniences, its effectiveness and natural flavoring make it a strong candidate for maintaining your dog's dental hygiene.

The Arm & Hammer for Pets Tartar Control Kit offers a convenient 3-piece set including toothpaste, toothbrush, and finger brush, designed to reduce plaque and tartar buildup while promoting healthier gums and fresher breath. Its toothpaste contains natural ingredients and baking soda, which helps gently clean teeth and brighten them without harsh chemicals, making it safe for dogs of all ages and sizes. The banana mint flavor is mild and generally appealing, which can help if your dog is hesitant about brushing.

A nice feature is the kit’s simple guidance for beginners, encouraging a gradual introduction to brushing, which makes it easier to establish a dental routine. In terms of texture and consistency, the toothpaste is designed to be easy to apply both directly on brush tools or a finger, offering flexibility according to your dog’s comfort level. Packaging is compact and straightforward, but it might not include a protective cap that some users prefer for freshness.

This kit suits pet owners looking for a gentle, easy-to-use dental care solution with familiar, safe ingredients, especially if your dog enjoys flavored toothpaste. For those seeking a product with stronger enzymatic action or explicit veterinary backing, other options may be preferable.

Petsmile Professional Pet Toothpaste is a non-enzymatic option for cleaning your dog's teeth, which sets it apart since most dog toothpastes rely on enzymes. Its standout feature is the VOHC (Veterinary Oral Health Council) acceptance, indicating it meets high dental care standards. The toothpaste uses a proprietary formula called Calprox, which helps prevent plaque, tartar, and gingivitis while whitening teeth and improving gum health.

The London Broil flavor could be appealing to pets, making it easier to use. Additionally, it's formulated with human-grade, hypoallergenic, and high-quality ingredients, ensuring safety for your pet. One of its key strengths is the no-brush requirement, as you just need to apply it on your pet's teeth and let their tongue do the cleaning, ideal for pets who resist brushing.

As it is non-enzymatic, it might not be as effective as enzymatic toothpastes for certain pets. The packaging is practical, and the product is free from harmful substances like bisphenol A, sulfates, gluten, and parabens, making it a safe option. Veterinary dentists often recommend it, giving it further credibility. If your pet has specific dental needs or prefers certain flavors, this toothpaste could be a good fit despite the lack of enzymes.