10 Best Enzyme Cleaners For Dog Urine 2025 in the United States

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is a versatile enzyme cleaner designed for removing dog urine and other pet-related stains and odors. Its high enzyme concentration effectively breaks down ammonia crystals and organic matter, ensuring thorough cleaning and odor elimination. The product is certified safe for use around pets and children, making it a reliable choice for households with furry friends.

It works on a variety of surfaces including carpets, floors, furniture, and pet living areas, providing a comprehensive cleaning solution. Eco-conscious users will appreciate that it is chlorine-free, color-safe, and leaves no hazardous residue. The original scent is mild and non-overpowering. The cleaner is straightforward to use, requiring a simple spray on the affected area and some drying time, which can vary depending on the surface and stain severity.

The 128 Fl Oz size might be cumbersome for some users to handle due to its weight. Additionally, its relatively high cost may be a consideration for budget-conscious consumers. This product is best suited for pet owners looking for an efficient, eco-friendly cleaning solution that is safe for both their animals and their household.

The ANGRY ORANGE Pet Odor Eliminator is designed to tackle pet urine and other unpleasant smells, specifically targeting cat urine. The product comes in a 24 oz spray bottle with a fresh orange scent, making it pleasant to use and effective in masking odors. One of its strengths is the ease of use due to its spray form, which requires no additional setup or mixing. Simply spray the affected area and let the formula work its magic.

It's also noteworthy that the product has a responsive customer service team to address any dissatisfaction, ensuring a satisfactory user experience. Surface compatibility is another important aspect, and while the product is generally safe for various surfaces, users should test it on a small hidden area first to avoid any damage. The fresh scent is a significant plus for those sensitive to strong chemicals, but it might not completely eliminate the odor for everyone, depending on the severity of the issue.

This product is best suited for pet owners dealing with recurring odor issues and those who prefer a simple and pleasant-smelling solution.

Angry Orange Stain Remover is a 32oz enzyme pet cleaner designed to tackle dog and cat urine stains effectively. With a strong enzyme concentration, it breaks down and eliminates stains from pet urine, feces, and vomit rather than merely masking them. This makes it a powerful tool for dealing with pet-related messes.

Its multipurpose nature means it can be used on various surfaces like carpet, tile, hardwood, couch upholstery, car interiors, and even turf. This versatility is a considerable advantage for pet owners who need a comprehensive cleaning solution across different areas of their home and belongings. The product boasts a pleasant citrus scent, which can leave your cleaned areas smelling fresh and appealing, an added benefit for maintaining a pleasant home environment.

Ease of use is another highlight, with simple directions: remove pets from the area, clean excess mess, shake well, spray, and let the enzymes work. Lastly, the product’s customer service is noted as responsive, ensuring any dissatisfaction is promptly addressed. However, the origin of the product is China, which may be a point of consideration for some consumers concerned about manufacturing standards or preferring locally-made products.