We Use CookiesWe use cookies to enhance the security, performance, functionality and for analytical and promotional activities. By continuing to browse this site you are agreeing to our privacy policy

10 Best Enzyme Pet Cleaners 2025 in the United States

How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

headphones-stars

Our Top Picks

#1

Winner

Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

Rating
9.9
Chosen by1,453
Surface Compatibility
Scent

Most important from
119218 reviews

Surface Compatibility
Works effectively on a variety of surfaces including hardwood, carpets, furniture, and even clothing.
Scent
The scent of the product is pleasant and not overwhelming, with a subtle floral hint.

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is a versatile enzyme pet cleaner designed for removing tough stains and odors from various surfaces. It uses natural enzymes that activate on contact with stains and odors, effectively breaking down ammonia crystals and organic matter. This makes it a strong choice for tackling pet accidents like urine, feces, and vomit.

The product is certified gentle and safe, chlorine-free, and leaves no residue, which is a big plus for households with children and multiple pets. It is also color-safe and approved by the Carpet and Rug Institute, ensuring it won't damage your carpets. The cleaner is suitable for a wide range of surfaces, including carpets, floors, furniture, and even pet living areas like kennels and litter boxes, making it highly versatile.

However, its original scent may not appeal to everyone, and the drying time can vary depending on the surface and the amount used. Additionally, while it is eco-friendly in terms of being chemical-free, it does come in a plastic bottle, which may be a concern for environmentally conscious buyers. The product is backed by a satisfaction guarantee, providing peace of mind for users who want to ensure they are getting value for their money.

Rating
9.9
Chosen by1,453
Surface Compatibility
Scent

Most important from
119218 reviews

Surface Compatibility
Works effectively on a variety of surfaces including hardwood, carpets, furniture, and even clothing.
Scent
The scent of the product is pleasant and not overwhelming, with a subtle floral hint.
#2

Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 1 Gallon

Rating
9.8
Scent
Application Method

Most important from
7613 reviews

Scent
People complimented how good my house smelled; even visitors couldn't tell I had cats.
Application Method
The product is concentrated and ready-to-use, making it very convenient.

The ANGRY ORANGE Pet Odor Eliminator is designed to tackle tough pet odors with a powerful citrus scent derived from fresh orange peels. One of its major strengths is its effectiveness; a small amount can target and destroy strong, lingering smells at their source, making it a great option for pet owners facing persistent odor issues. This product is ready to use straight from the bottle, which means there's no need for mixing or diluting, adding to its convenience.

Application is straightforward: simply shake well, spray on the affected area, and let it dry completely. However, it's important to note that pets should be removed from the area during application, and the product should not be used directly on pets or in diffusers, as it can be too strong for cats and birds due to concentrated ingredients. The citrus scent is pleasant and helps mask unpleasant odors, making the environment more enjoyable.

In terms of versatility, it can be used on various surfaces like carpets, tiles, upholstery, and even in garbage cans and car interiors. This makes it a multipurpose cleaner beyond just pet-related messes. The ANGRY ORANGE Pet Odor Eliminator is an effective and versatile option for tackling pet odors, though users should be mindful of its concentrated nature and ensure it's used as directed.

Rating
9.8
Scent
Application Method

Most important from
7613 reviews

Scent
People complimented how good my house smelled; even visitors couldn't tell I had cats.
Application Method
The product is concentrated and ready-to-use, making it very convenient.
#3

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

Rating
9.5
Surface Compatibility
Scent
Application Method

Most important from
28468 reviews

Surface Compatibility
The enzyme cleaner that smells like delicious citrus fruit is incredibly easy to use on so many surfaces!
Scent
The enzyme cleaner that smells like delicious citrus fruit is incredibly easy to use on so many surfaces!
Application Method
The sprayer quality can be hit or miss, with some bottles leaking.

The Angry Orange Stain Remover is a versatile enzyme pet cleaner designed to tackle tough pet messes. Its dual-action formula not only cleans but also eliminates pet odors from urine, feces, and vomit. This makes it particularly effective for households with dogs and cats. The citrus scent, derived from natural orange oils and enzymes, leaves a fresh, fruity aroma that many will find pleasant. The cleaner is safe for multiple surfaces, including carpets, hardwood floors, fabrics, and turf, making it a practical choice for various cleaning needs around the house. However, while it is safe for pets and children, it should not be sprayed directly on them.

The spray application method is convenient and easy to use, and the product is eco-friendly, aligning with a more natural cleaning approach. On the downside, some users might find the citrus scent too strong for their liking. Additionally, while the product claims to provide up to 80 hours of freshness, this may vary depending on the severity of the stains and odors. If you're looking for an effective, multi-surface pet stain and odor remover with a pleasant citrus scent, the Angry Orange Stain Remover could be a good addition to your cleaning supplies.

Rating
9.5
Surface Compatibility
Scent
Application Method

Most important from
28468 reviews

Surface Compatibility
The enzyme cleaner that smells like delicious citrus fruit is incredibly easy to use on so many surfaces!
Scent
The enzyme cleaner that smells like delicious citrus fruit is incredibly easy to use on so many surfaces!
Application Method
The sprayer quality can be hit or miss, with some bottles leaking.

Buying Guide for the Best Enzyme Pet Cleaners

Choosing the right enzyme pet cleaner can make a significant difference in maintaining a clean and odor-free home, especially if you have pets. Enzyme cleaners are specifically designed to break down organic materials like urine, feces, vomit, and other pet-related messes. They work by using natural enzymes to digest the proteins and bacteria that cause stains and odors. To find the best enzyme pet cleaner for your needs, consider the following key specifications and how they align with your specific requirements.
Enzyme TypeEnzyme type refers to the specific enzymes used in the cleaner. Different enzymes target different types of stains and odors. For example, proteases break down proteins, amylases break down starches, and lipases break down fats. It's important because the effectiveness of the cleaner depends on the type of mess you're dealing with. If your pet often has accidents involving urine, look for a cleaner with urease enzymes. For general messes, a cleaner with a combination of enzymes might be best. Choose based on the most common types of stains and odors you need to address.
Surface CompatibilitySurface compatibility indicates which surfaces the cleaner can be safely used on, such as carpets, hardwood floors, upholstery, or tiles. This is important because using the wrong cleaner on a surface can cause damage or be ineffective. Cleaners are often labeled for specific surfaces, so check the product description. If you need a versatile cleaner, look for one that is safe for multiple surfaces. Consider where your pet spends the most time and where accidents are most likely to happen to guide your choice.
ScentThe scent of the cleaner can affect how pleasant your home smells after use. Some enzyme cleaners have a strong fragrance to mask odors, while others are unscented or have a mild scent. This is important because a strong scent might be overwhelming or cause allergies. If you or your pet are sensitive to strong smells, opt for an unscented or lightly scented cleaner. If you prefer a fresh-smelling home, a cleaner with a pleasant fragrance might be more suitable. Choose based on your and your pet's scent preferences and sensitivities.
Application MethodThe application method refers to how the cleaner is applied, such as spray, pour, or foam. This is important because it affects ease of use and effectiveness. Sprays are convenient for spot cleaning, while pour bottles might be better for larger areas. Foam can penetrate deeper into carpets and upholstery. Consider how you will be using the cleaner most often. For quick clean-ups, a spray might be best. For deep cleaning, a foam or pour bottle might be more effective. Choose based on your cleaning habits and the types of messes you encounter.
Drying TimeDrying time is the amount of time it takes for the cleaner to dry after application. This is important because it affects how quickly you can use the cleaned area again. Faster drying times are more convenient, especially in high-traffic areas. Cleaners with longer drying times might be more effective for deep cleaning but require more planning. If you need quick results, look for a cleaner with a short drying time. For thorough cleaning, a longer drying time might be acceptable. Choose based on how quickly you need the area to be usable again.
Eco-FriendlinessEco-friendliness refers to how environmentally friendly the cleaner is, including biodegradable ingredients and recyclable packaging. This is important for reducing your environmental impact. Eco-friendly cleaners are often labeled as such and may use natural, non-toxic ingredients. If sustainability is important to you, look for products with eco-friendly certifications. Consider the environmental impact of the cleaner and choose one that aligns with your values. Eco-friendly options are also generally safer for pets and children.

FAQ

Most Popular Categories Right Now