10 Best Enzyme Stain Removers 2025 in the United States

The Puracy Stain Remover Cleaning Spray Refill is a versatile and eco-friendly option for dealing with a variety of stains. It is formulated with enzymes that powerfully tackle both fresh and set-in stains, making it effective on common stains like grass, red wine, makeup, and oil. One notable strength is its compatibility with a wide range of fabrics, from delicate linens to robust upholstery. This makes it a flexible and valuable addition to any household's cleaning arsenal.

Another significant advantage is its free-from formula, which avoids harsh chemicals such as sulfates, parabens, bleaches, and petrochemicals. This ensures safety for both users and the environment, making it a great choice for households with children and pets. Additionally, the product is unscented ('Free & Clear'), which is beneficial for those sensitive to fragrances. However, a potential drawback might be the need for a separate spray bottle, as this is a refill product.

Furthermore, while the eco-friendly and gentle formulation is a plus, it might require more applications for particularly stubborn stains compared to stronger chemical-based alternatives. In terms of convenience, its liquid form and generous 48 fl oz size provide ample supply, but it could be less portable for those who need a more compact travel-size option. The Puracy Stain Remover Cleaning Spray Refill is best suited for eco-conscious users looking for a gentle yet effective stain remover that is safe for a variety of fabrics and household members.

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is a versatile enzyme stain remover that is especially beneficial for pet owners dealing with stubborn stains and odors from urine, feces, and vomit. It uses natural enzymes that activate on contact with stains and odors, effectively breaking down and eliminating them. This product is gentle and safe to use around pets and children, being chlorine-free and color-safe.

It’s also been certified by the Carpet and Rug Institute, ensuring it does not damage carpets or leave behind any residue. This makes it suitable for a wide range of surfaces, including carpets, floors, furniture, clothing, and pet living areas. The product comes in a 32oz spray bottle, which is user-friendly and convenient for application. However, some users may find the original scent either neutral or not particularly appealing.

The eco-friendliness of this product adds another layer of appeal, as it does not contain hazardous chemicals. Nonetheless, the main drawback is its relatively higher price point, which might not fit every budget. Despite this, the satisfaction guarantee and refund policy provided by the manufacturer offer additional peace of mind for users. This product is a solid choice for those who prioritize effective and safe cleaning solutions for pet-related stains and odors.

The Puracy Stain Remover is a versatile and eco-friendly option for tackling a variety of stains on different fabric types. One of its key strengths is its gentle yet effective formulation, which can handle both fresh and set-in stains from common culprits like grass, red wine, makeup, and oil. This makes it particularly useful for households with children and pets, where accidents are more likely to happen.

The formula is free from harsh chemicals such as sulfates, parabens, bleaches, and petrochemicals, ensuring safety for both users and the environment. This could appeal to eco-conscious consumers and those with sensitive skin or allergies. Additionally, the product is designed for universal fabric compatibility, making it suitable for everything from delicate linens to sturdy upholstery, which adds to its versatility.

The 12 oz size is convenient for travel and everyday use, but may not be sufficient for larger households or heavy-duty stain removal needs. This product is well-suited for individuals looking for a safe, eco-friendly, and versatile stain remover that can be used across various fabrics and stains, although it may not cater to those with specific enzyme requirements or a preference for scented cleaners.