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10 Best Stool Softeners 2025 in the United States

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Our Top Picks

#1

Winner

MiraLAX Gentle Constipation Relief Laxative Powder, Stool Softener with PEG 3350, Works Naturally with Water in Your Body, No Harsh Side Effects, Osmotic Laxative, 45 Dose

Rating
9.9
Chosen by1,266
Onset of Action

Most important from
36913 reviews

Onset of Action
Works wonders and is gentle, perfect for consistent relief.

MiraLAX Gentle Constipation Relief Laxative Powder is designed to help those experiencing occasional constipation. One of its strong points is that it works as an osmotic laxative, using water in your body to hydrate and soften stool, typically producing results within 1-3 days. This approach is gentle compared to stimulant laxatives, which can cause immediate urgency and discomfort. Users will appreciate that MiraLAX generally doesn’t lead to common side effects such as gas, bloating, or cramping, making it a suitable choice for those looking for a milder option.

The product is also highly regarded, being the #1 physician-recommended over-the-counter laxative since its introduction in 2007, which speaks to its reliability and effectiveness. It contains no added sugars, gluten, or preservatives, catering to individuals with specific dietary needs. Additionally, the powder easily dissolves in various beverages without altering the taste, making it convenient for users.

On the downside, some may find the onset of action slower than they desire, especially if they are accustomed to stimulant laxatives that provide quicker results. While its gentle nature is an advantage, some individuals might need to wait longer for relief. As with any laxative, it's important to use it as directed and consult a healthcare professional if constipation persists.

Rating
9.9
Chosen by1,266
Onset of Action

Most important from
36913 reviews

Onset of Action
Works wonders and is gentle, perfect for consistent relief.
#2

Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder for Solution, Osmotic Laxative, Relieves Occasional Constipation, Unflavored, 1.68 pound (Pack of 1)

Rating
9.8
Dosage Form
Onset of Action
Brand Reputation

Most important from
35639 reviews

Dosage Form
This powder can be mixed with puddings, shakes, water, milk, and other beverages without altering their taste or texture.
Onset of Action
Works like magic in coffee, making bowel movements smooth and easy without any urgent emergencies.
Brand Reputation
A terrific value for money, offering more doses than the brand-name alternative, Miralax.

Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder is designed to help relieve occasional constipation with an effective, doctor-recommended active ingredient. One of its standout strengths is the active component, Polyethylene Glycol 3350, which is known to be the number one recommended laxative ingredient by physicians. Users can typically expect a bowel movement within 1 to 3 days, making it a reliable choice for those needing prompt relief.

The product's unflavored powder form allows for easy mixing with any beverage, catering to individual preferences without adding extra flavors or sugars. It is also gluten-free and grit-free, which can be a plus for those with dietary restrictions or sensitivities. This makes it suitable for adults and children aged 17 and older.

There are a few considerations to keep in mind. While the unflavored aspect can appeal to many, some users may find it less enjoyable to consume compared to flavored alternatives. Additionally, since it's a powder, it requires the user to mix it properly into a liquid, which might be less convenient for some individuals who prefer pre-mixed solutions. Another point worth noting is that while this product works well for occasional constipation, it may not be suitable for more severe or chronic issues without a doctor's guidance. Also, as with any laxative, there is the potential for side effects, like cramping or bloating, which some users may experience.

Amazon Basic Care ClearLax Polyethylene Glycol 3350 is a solid choice for those looking for a reliable, effective, and doctor-recommended stool softener for occasional use. Its ease of use in beverage form and strong brand backing make it a practical option, though users should be aware of the potential for discomfort and the need for proper mixing.

Rating
9.8
Dosage Form
Onset of Action
Brand Reputation

Most important from
35639 reviews

Dosage Form
This powder can be mixed with puddings, shakes, water, milk, and other beverages without altering their taste or texture.
Onset of Action
Works like magic in coffee, making bowel movements smooth and easy without any urgent emergencies.
Brand Reputation
A terrific value for money, offering more doses than the brand-name alternative, Miralax.
#3

Colace Regular Strength Stool Softener 100 mg Capsules 100 Count Docusate Sodium Stimulant-Free for Gentle, Dependable Occasional Constipation Relief

Rating
9.6
Dosage Form
Onset of Action

Most important from
13984 reviews

Dosage Form
Works well when taking strong pain meds after surgery, and the coated pills are easy to swallow.
Onset of Action
Did the job just fine after a surgical procedure, though it could take 12 or more hours to take effect.

Colace Regular Strength Stool Softener is a well-regarded option for those seeking gentle relief from occasional constipation. With its active ingredient, docusate sodium, it works by easing the passage of stool without the cramping associated with stimulant laxatives. This makes it particularly suitable for individuals who may be sensitive to harsher laxatives, including pregnant or postpartum women. The capsules are easy to take and are designed to provide relief within 12 to 72 hours, which is a reasonable timeframe for many users.

One of the standout features of Colace is its strong reputation; being the most recommended brand by doctors, including OB-GYNs and gastroenterologists, gives it a level of trustworthiness that many consumers value. Moreover, it is FSA/HSA eligible, which can be a financial boon for users.

While it’s effective for occasional constipation relief, there are a couple of considerations to keep in mind. Some users may find that it takes longer to work compared to stimulant options, especially if they're dealing with severe constipation. Additionally, it may not be suitable for everyone, and it’s always wise to consult a healthcare professional, especially during pregnancy or breastfeeding.

Rating
9.6
Dosage Form
Onset of Action

Most important from
13984 reviews

Dosage Form
Works well when taking strong pain meds after surgery, and the coated pills are easy to swallow.
Onset of Action
Did the job just fine after a surgical procedure, though it could take 12 or more hours to take effect.

Buying Guide for the Best Stool Softeners

Choosing the right stool softener can make a significant difference in your digestive health and overall comfort. Stool softeners are used to relieve constipation by making bowel movements easier to pass. When selecting a stool softener, it's important to consider several key factors to ensure you choose the best product for your needs. Here are the key specifications to consider and how to navigate them.
Active IngredientThe active ingredient in a stool softener is the component that helps to soften the stool. Common active ingredients include docusate sodium and docusate calcium. This spec is important because different active ingredients can work differently for various individuals. If you have a known sensitivity or preference, this can guide your choice. For example, docusate sodium is widely used and generally well-tolerated, while docusate calcium might be preferred by those who need a calcium supplement.
Dosage FormStool softeners come in various forms such as capsules, tablets, liquid, and powder. This spec is important because it affects how you take the medication and how quickly it works. Capsules and tablets are convenient and easy to take, while liquids and powders can be mixed with water or juice, which might be easier for some people to ingest. Choose the form that you find most convenient and comfortable to use.
StrengthThe strength of a stool softener refers to the amount of active ingredient per dose. This spec is important because it determines how effective the product will be for you. Strengths can vary, with common doses ranging from 50 mg to 250 mg. If you have mild constipation, a lower strength might be sufficient, while more severe cases might require a higher strength. Always start with the lowest effective dose and consult with a healthcare provider if you are unsure.
Onset of ActionThe onset of action is the time it takes for the stool softener to start working. This spec is important because it affects how quickly you can expect relief. Some stool softeners may take 12 to 72 hours to work. If you need quick relief, look for products with a faster onset of action. However, if you are looking for a more gradual effect, a slower onset might be more appropriate.
Additional IngredientsSome stool softeners contain additional ingredients such as flavorings, sweeteners, or other medications. This spec is important because these additional ingredients can affect tolerability and effectiveness. For example, if you have dietary restrictions or allergies, you will need to check for any potential allergens. If you prefer a natural product, look for stool softeners with minimal additional ingredients.
Brand ReputationThe reputation of the brand can be an indicator of the quality and reliability of the stool softener. This spec is important because well-established brands are more likely to have undergone rigorous testing and quality control. Researching customer reviews and ratings can help you gauge the effectiveness and safety of the product. Choose a brand that is well-reviewed and trusted by other users.

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