10 Best Stool Softeners 2025 in the United States

MiraLAX Gentle Constipation Relief Laxative Powder is designed to help those experiencing occasional constipation. One of its strong points is that it works as an osmotic laxative, using water in your body to hydrate and soften stool, typically producing results within 1-3 days. This approach is gentle compared to stimulant laxatives, which can cause immediate urgency and discomfort. Users will appreciate that MiraLAX generally doesn’t lead to common side effects such as gas, bloating, or cramping, making it a suitable choice for those looking for a milder option.

The product is also highly regarded, being the #1 physician-recommended over-the-counter laxative since its introduction in 2007, which speaks to its reliability and effectiveness. It contains no added sugars, gluten, or preservatives, catering to individuals with specific dietary needs. Additionally, the powder easily dissolves in various beverages without altering the taste, making it convenient for users.

On the downside, some may find the onset of action slower than they desire, especially if they are accustomed to stimulant laxatives that provide quicker results. While its gentle nature is an advantage, some individuals might need to wait longer for relief. As with any laxative, it's important to use it as directed and consult a healthcare professional if constipation persists.

The GenCare Senna-S combines two active ingredients: sennosides, a natural vegetable laxative, and docusate sodium, a stool softener. This dual action helps relieve occasional constipation by promoting bowel movements and softening stools, making passing easier and more comfortable. The product comes as easy-to-swallow oral tablets, which many find preferable to suppositories or liquids.

Typically, it works within 6 to 12 hours, making it suitable for overnight relief. The packaging offers a large value pack with 200 tablets, which is cost-effective for families or those needing regular use. While the brand is a generic alternative to Senokot-S, it maintains the same effective ingredients. The recommended dose should be followed carefully, especially for children, and a doctor should be consulted for young kids under 2 years old. Some users may find the onset of relief a bit slow if immediate results are needed.

This product is a good choice for people wanting a natural, dependable, and budget-friendly stool softener that works gently overnight.

Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder is designed to help relieve occasional constipation with an effective, doctor-recommended active ingredient. One of its standout strengths is the active component, Polyethylene Glycol 3350, which is known to be the number one recommended laxative ingredient by physicians. Users can typically expect a bowel movement within 1 to 3 days, making it a reliable choice for those needing prompt relief.

The product's unflavored powder form allows for easy mixing with any beverage, catering to individual preferences without adding extra flavors or sugars. It is also gluten-free and grit-free, which can be a plus for those with dietary restrictions or sensitivities. This makes it suitable for adults and children aged 17 and older.

There are a few considerations to keep in mind. While the unflavored aspect can appeal to many, some users may find it less enjoyable to consume compared to flavored alternatives. Additionally, since it's a powder, it requires the user to mix it properly into a liquid, which might be less convenient for some individuals who prefer pre-mixed solutions. Another point worth noting is that while this product works well for occasional constipation, it may not be suitable for more severe or chronic issues without a doctor's guidance. Also, as with any laxative, there is the potential for side effects, like cramping or bloating, which some users may experience.

Amazon Basic Care ClearLax Polyethylene Glycol 3350 is a solid choice for those looking for a reliable, effective, and doctor-recommended stool softener for occasional use. Its ease of use in beverage form and strong brand backing make it a practical option, though users should be aware of the potential for discomfort and the need for proper mixing.