10 Best Stool Softeners 2026 in the United States

Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder is designed to help relieve occasional constipation with an effective, doctor-recommended active ingredient. One of its standout strengths is the active component, Polyethylene Glycol 3350, which is known to be the number one recommended laxative ingredient by physicians. Users can typically expect a bowel movement within 1 to 3 days, making it a reliable choice for those needing prompt relief.

The product's unflavored powder form allows for easy mixing with any beverage, catering to individual preferences without adding extra flavors or sugars. It is also gluten-free and grit-free, which can be a plus for those with dietary restrictions or sensitivities. This makes it suitable for adults and children aged 17 and older.

There are a few considerations to keep in mind. While the unflavored aspect can appeal to many, some users may find it less enjoyable to consume compared to flavored alternatives. Additionally, since it's a powder, it requires the user to mix it properly into a liquid, which might be less convenient for some individuals who prefer pre-mixed solutions. Another point worth noting is that while this product works well for occasional constipation, it may not be suitable for more severe or chronic issues without a doctor's guidance. Also, as with any laxative, there is the potential for side effects, like cramping or bloating, which some users may experience.

Amazon Basic Care ClearLax Polyethylene Glycol 3350 is a solid choice for those looking for a reliable, effective, and doctor-recommended stool softener for occasional use. Its ease of use in beverage form and strong brand backing make it a practical option, though users should be aware of the potential for discomfort and the need for proper mixing.

MiraLAX Gentle Constipation Relief Laxative Powder is designed to help those experiencing occasional constipation. One of its strong points is that it works as an osmotic laxative, using water in your body to hydrate and soften stool, typically producing results within 1-3 days. This approach is gentle compared to stimulant laxatives, which can cause immediate urgency and discomfort. Users will appreciate that MiraLAX generally doesn’t lead to common side effects such as gas, bloating, or cramping, making it a suitable choice for those looking for a milder option.

The product is also highly regarded, being the #1 physician-recommended over-the-counter laxative since its introduction in 2007, which speaks to its reliability and effectiveness. It contains no added sugars, gluten, or preservatives, catering to individuals with specific dietary needs. Additionally, the powder easily dissolves in various beverages without altering the taste, making it convenient for users.

On the downside, some may find the onset of action slower than they desire, especially if they are accustomed to stimulant laxatives that provide quicker results. While its gentle nature is an advantage, some individuals might need to wait longer for relief. As with any laxative, it's important to use it as directed and consult a healthcare professional if constipation persists.

Colace Clear Stool Softener is a trusted choice for those needing gentle relief from constipation. Its active ingredient, Docusate Sodium at 50 mg per capsule, is well-known for safely increasing water in the stool, helping to soften it and making bowel movements easier. The soft gel form is easy to swallow, and the product is dye and stimulant free, which means it's less likely to cause cramping or discomfort compared to some other laxatives. This makes it a good option for sensitive users, including pregnant women or people recovering from surgery.

The onset of action typically ranges from 12 to 72 hours, so it is not immediate but works within a reasonable timeframe for stool softeners. Being the #1 doctor-recommended stool softener brand adds to its reliability and reputation. However, Colace is designed to gently ease occasional constipation rather than provide quick relief for severe cases. Also, since it’s free from stimulants, it will not prompt strong intestinal contractions, meaning it might not work fast enough if urgent relief is needed.

Colace Clear Stool Softener is best suited for those looking for a mild, dependable, and doctor-trusted product to manage occasional constipation without harsh side effects.