10 Best Supplements For Lean Muscle Mass 2025 in the United States

Optimum Nutrition Gold Standard 100% Whey Protein Powder in Vanilla Ice Cream flavor is a popular choice for those looking to support lean muscle mass. It offers 24 grams of protein per serving, which includes a blend of whey protein isolate, whey protein concentrate, and whey peptides. This combination is effective for muscle repair and growth. Additionally, it contains over 5 grams of BCAAs (Branched-Chain Amino Acids), which are vital for muscle recovery and building lean muscles.

The low carbohydrate (3-4 grams) and fat content (1-1.5 grams) make it a suitable option for those monitoring their macronutrient intake, and it's also gluten-free. Users may appreciate that this product does not contain sucralose in the double rich chocolate flavor, though this review is for the vanilla ice cream variant. The mixability is excellent due to the instantized formula, reducing the chance of lumps and clumps when mixed with liquids. However, some might find the flavor too sweet or artificial, which is common with protein powders.

Optimum Nutrition has a strong brand reputation for quality and reliability, having been in the market since 1999. The packaging may vary but the product's quality remains consistent. Each container provides about 29 servings, making it a reasonable choice for regular use. This whey protein powder is well-suited for anyone focused on building and maintaining lean muscle mass, though it may not be ideal for those who prefer plant-based proteins or have specific dietary restrictions.

The Naked Vanilla Naked Mass Weight Gainer Protein Powder is a solid option for those looking to gain lean muscle mass. With 50g of protein per serving, it boasts a significant amount of protein, combining both whey and casein for a balanced release. This ensures sustained protein synthesis, which is beneficial for muscle growth. Additionally, it includes 252g of carbohydrates primarily from organic tapioca maltodextrin, providing clean energy without gluten, GMO, or artificial ingredients.

The 11.5g of branched-chain amino acids (BCAAs) per serving further supports muscle recovery and growth. The relatively low sugar content (5g) is an advantage as well, making it a healthier choice compared to some other weight gainers that are high in sugar. However, at 1,250 calories per serving, it is very calorie-dense, which may not be suitable for everyone, especially those who do not have high caloric needs or are not engaging in intense exercise. Mixability and flavor seem to be strengths here, with its vanilla flavor being versatile for various recipes and shakes.

Naked Nutrition, the brand behind the product, is known for its commitment to clean, high-quality ingredients, adding to the product's appeal. On the downside, the high carbohydrate content might be a drawback for those looking for a lower-carb option, and the price point might be higher compared to some other weight gainers. This product is best suited for adults who are hard gainers and need a high-calorie supplement to support their muscle-building goals.

BSN SYNTHA-6 Whey Protein Powder stands out with its comprehensive protein matrix, offering 22g of protein per serving sourced from a blend of whey protein concentrate, whey protein isolate, calcium caseinate, micellar casein, milk protein isolate, and egg albumin. This diverse mix of proteins ensures a steady release of amino acids, which is beneficial for muscle growth and recovery. The product also provides 10g of essential amino acids per serving, supporting your fitness and nutrition goals effectively.

With 190-200 calories and only 2-3g of sugar per serving, it caters well to those looking to build lean muscle while keeping calorie and sugar intake in check. One of its highlights is its flavor and mixability, with the chocolate milkshake variety being particularly praised for its taste, making it an enjoyable part of your diet whether post-workout, as a snack, or between meals. However, some users may find the calorie content slightly higher compared to other lean muscle-focused supplements.

Additionally, while it is gluten-free, it may not be suitable for those with other dietary restrictions due to its protein sources. The brand BSN has a strong reputation for quality, and this product is no different, manufactured by Glanbia Performance Nutrition, a reputable name in the industry. For those prioritizing taste, diverse protein types, and a balanced amino acid profile, BSN SYNTHA-6 is a great choice, although considering the higher calorie content is important if you are strictly monitoring your caloric intake.