10 Best Allergy Mattress Covers 2025 in the United States

The SafeRest CloudGuard Twin XL Mattress Protector is designed to offer an ultra-comfortable sleeping experience with its plush and fluffy quilted pillow top. As an allergy-mattress cover, it performs impressively with its allergen barrier, thanks to the thick padding that helps block dust mites and other allergens. The material used, CloudGuard (Ultra Padded), ensures a luxurious feel while maintaining a breathable environment, which is crucial for a comfortable sleep.

One of the significant strengths of this product is its 100% waterproof membrane, which safeguards the mattress against fluids, urine, and perspiration, keeping it dry and clean. This feature is particularly beneficial for households with children or pets. The mattress protector is machine washable, making it easy to clean and maintain, a convenience for busy users. In terms of fit, the Twin XL size with dimensions of 80 x 39 x 14 inches and a pull-on closure type ensures a snug fit on most Twin XL mattresses. The noiseless feature of the fabric further enhances the sleeping experience by eliminating any crinkling sounds common in other mattress protectors.

However, there are a few considerations to keep in mind. The product’s thickness and plush nature might make it less breathable compared to thinner mattress covers, which could be a drawback for those who tend to sleep hot. Additionally, although it claims to be noiseless, individual experiences may vary, and some users might still notice slight noise upon movement. Despite these minor drawbacks, the SafeRest CloudGuard stands out as a high-quality choice for those seeking a combination of comfort and protection in their mattress cover, particularly beneficial for allergy sufferers and families.

The SureGuard King Size Mattress Protector is a strong choice for anyone looking to keep their mattress clean and allergy-free. Made from soft, breathable cotton terry, it provides a comfortable surface that doesn’t feel plastic or noisy like some waterproof covers. It’s fully waterproof, protecting against spills, perspiration, and bedwetting, which can help extend the life of your mattress. This cover also acts as a good allergen barrier, blocking dust, dirt, and pet dander, making it suitable for people sensitive to allergens.

Its fitted sheet style with a stretchable skirt fits mattresses up to 17 inches deep well, ensuring it stays in place without bunching. Cleaning is convenient since it’s machine washable and dries quickly, which is helpful for regular use. The product is free from harmful chemicals, adding peace of mind for those with sensitivities.

While it is soft and quiet, very hot sleepers might find cotton less breathable than some advanced synthetic options, which could trap heat. Also, because it’s a fitted sheet style, it may require occasional adjustment to keep tight on the mattress. For a hypoallergenic, durable, and easy-to-maintain mattress protector, the SureGuard offers a reliable solution that covers all the key points for allergy mattress covers well.

The PlushDeluxe Premium Bamboo Mattress Protector is a strong contender in the allergy mattress cover category, particularly for those who prioritize comfort and protection. One of its key strengths is its hypoallergenic properties, making it ideal for allergy sufferers and anyone looking to reduce allergens in their sleeping environment. The use of natural bamboo fabric not only provides a soft feel but also promotes breathability, ensuring a cool and comfortable sleep. Its waterproof feature is impressive, effectively resisting fluids from spills or bodily accidents, which can be particularly beneficial for families with young children or pets.

In terms of fit, the protector is designed to accommodate a variety of mattress types and depths, going up to 18 inches, which adds versatility. Plus, it remains noiseless, a bonus for those who are sensitive to sounds while sleeping. The ease of cleaning is another highlight, as it's washable and maintains its quality over time.

Some potential drawbacks should be noted. While the bamboo material is generally durable, it may not be as robust as some synthetic options on the market, which could affect longevity. Additionally, although the protector is marketed as waterproof, it may not offer the same level of protection as thicker, more traditional waterproof covers. Lastly, while the white color looks clean, it may show stains more readily than darker options, potentially requiring more frequent washes to maintain its appearance.