10 Best Anxiety Relief For Cats 2025 in the United States

FELIWAY MultiCat Calming Pheromone is designed to help reduce tension and conflict between multiple cats by mimicking a mother cat’s natural pheromones. It is drug-free and non-sedating, making it a safe option for cats without affecting humans or other pets. The product is easy to use; you simply plug the diffuser into an outlet, ensuring it has 4+ feet of space around it for optimal diffusion. This diffuser releases calming pheromones continuously for 30 days, making it convenient for busy pet owners.

One of its strengths is that it’s developed by a brand supported by over 25 years of feline stress expertise and research, which adds to its credibility. Additionally, 84% of cat owners reported significant improvement in cat conflicts. However, it’s important to note that the diffuser and refill are specific to the FELIWAY brand, so you cannot use other brands’ refills with this diffuser.

Also, to achieve the best results, you need to use one diffuser per 700 square feet, replace the vial monthly, and the diffuser every six months, which could add up in costs over time. This product is particularly beneficial for households with multiple cats experiencing frequent conflicts and needing a non-medicinal intervention.

The FELIWAY Optimum Cat Enhanced Calming Pheromone Diffuser is designed to help alleviate common stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. This product uses patented pheromone technology and is drug-free, making it a safe choice for your cat without affecting humans or other pets in the household. It's particularly beneficial for multi-cat households experiencing conflicts between cats or for cats with pronounced stress indicators.

The diffuser is simple to use: just plug it into an open outlet with adequate surrounding space, and it will release calming pheromones continuously for up to 30 days, covering an area of up to 700 square feet. However, you must ensure the diffuser is placed in the room where your cat spends most of its time for optimal results and avoid placing it near litter boxes or behind furniture which can obstruct its effectiveness. One notable drawback is the need to replace the vial monthly and the diffuser every six months, which can add to the long-term cost. Also, the diffuser and refills are only compatible with FELIWAY products, limiting flexibility.

This product is well-suited for cat owners looking for a non-invasive, effective solution to help reduce their pet’s stress.

The Comfort Zone MultiCat Diffuser Refills are designed to help alleviate anxiety in cats, especially in households with multiple cats. This product uses cat calming pheromones, which are drug-free and fragrance-free, making it a safe option for managing feline stress without the use of medication. Each refill lasts for about 30 days, and the pack includes six refills, providing six months of continuous support.

The refills are compatible exclusively with Comfort Zone diffusers, which can cover up to 400 square feet per device. The diffusers themselves are reusable for up to 12 months, thus offering a cost-effective solution over time. However, it requires a proper placement to function effectively, and improper use might cause issues like vapor buildup or leaking. Additionally, the need to replace the diffuser unit annually and the limitation of one diffuser per room might be inconvenient for some users.

This product could be particularly beneficial for households dealing with multi-cat conflicts, as it helps reduce aggressive behaviors like swatting, scratching, and hissing.