10 Best Anxiety Relief For Cats 2025 in the United States

VETRISCIENCE Veterinary Strength Calm & Confident Chews are designed as a stress-relief supplement suitable for both cats and dogs, including all breeds and life stages. These chews contain calming ingredients such as L-Theanine and Thiamine, which support brain function and promote calm behavior without causing drowsiness or altering your pet’s personality. The chicken flavor and rawhide-free formula make them generally appealing and safe for cats, which can be picky or sensitive.

They are easy to administer, with dosage that can be adjusted based on the pet's weight or stress level, providing flexibility for everyday use or during high-stress situations. The product is veterinary strength and science-backed, and it is marketed for both cats and dogs.

These chews provide a convenient, well-reviewed option for cat owners seeking to ease anxiety during common stressful events like travel or vet visits. Pet owners should observe their cat’s response to determine optimal dosing and effectiveness.

The FELIWAY Optimum Cat Enhanced Calming Pheromone Diffuser is designed to help alleviate common stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. This product uses patented pheromone technology and is drug-free, making it a safe choice for your cat without affecting humans or other pets in the household. It's particularly beneficial for multi-cat households experiencing conflicts between cats or for cats with pronounced stress indicators.

The diffuser is simple to use: just plug it into an open outlet with adequate surrounding space, and it will release calming pheromones continuously for up to 30 days, covering an area of up to 700 square feet. However, you must ensure the diffuser is placed in the room where your cat spends most of its time for optimal results and avoid placing it near litter boxes or behind furniture which can obstruct its effectiveness. One notable drawback is the need to replace the vial monthly and the diffuser every six months, which can add to the long-term cost. Also, the diffuser and refills are only compatible with FELIWAY products, limiting flexibility.

This product is well-suited for cat owners looking for a non-invasive, effective solution to help reduce their pet’s stress.

The Comfort Zone MultiCat Diffuser Refills are designed to help alleviate anxiety in cats, especially in households with multiple cats. This product uses cat calming pheromones, which are drug-free and fragrance-free, making it a safe option for managing feline stress without the use of medication. Each refill lasts for about 30 days, and the pack includes six refills, providing six months of continuous support.

The refills are compatible exclusively with Comfort Zone diffusers, which can cover up to 400 square feet per device. The diffusers themselves are reusable for up to 12 months, thus offering a cost-effective solution over time. However, it requires a proper placement to function effectively, and improper use might cause issues like vapor buildup or leaking. Additionally, the need to replace the diffuser unit annually and the limitation of one diffuser per room might be inconvenient for some users.

This product could be particularly beneficial for households dealing with multi-cat conflicts, as it helps reduce aggressive behaviors like swatting, scratching, and hissing.