10 Best Arthritis Creams 2026 in the United States

Biofreeze Cream is a menthol-based topical pain reliever widely recommended by healthcare professionals for muscle and joint pain, including arthritis-related discomfort. Its main active ingredient, menthol, provides a cooling sensation that helps reduce minor aches from arthritis, strains, bruises, and back or neck pain. The cream is non-greasy and absorbs quickly, which makes it convenient for daily use without leaving a heavy residue. It also contains natural moisturizers, helping to avoid dry or irritated skin—a common concern with frequent topical applications.

The scent is typical of menthol products: refreshing but noticeable, which some users appreciate for the cooling effect, while others might find it a bit strong. Biofreeze is free of common pain relief drugs like NSAIDs, aspirin, or ibuprofen, making it suitable for people who want to avoid those ingredients or have sensitivities. Relief lasts for a few hours, offering targeted pain control, though it typically requires reapplication for ongoing issues. The cream’s 3-ounce jar is TSA-friendly and portable, ideal for those who need on-the-go pain management.

It is effective for mild to moderate arthritis pain and related muscle soreness, but it does not offer deep or long-lasting relief for severe cases. Some users may also find the cooling effect too intense initially. Biofreeze Cream is a solid choice for arthritis sufferers looking for quick, easy-to-apply cooling relief without medication, especially if you prefer a product trusted by healthcare professionals and free from harsh chemicals.

The Voltaren Arthritis Pain Gel is a popular choice for those seeking relief from arthritis pain. It stands out because it is the number one doctor-recommended brand for topical pain relief, which adds credibility to its effectiveness. The active ingredient is a nonsteroidal anti-inflammatory drug (NSAID), which means it not only provides pain relief but also tackles inflammation directly at its source. This is especially beneficial for reducing stiffness and improving mobility.

Users can expect significant relief within seven days of continuous use, with the product needing to be applied four times daily for the best results. The gel can be used on various joints, including hands, wrists, elbows, ankles, feet, and knees, making it versatile for different types of arthritis pain. The packaging includes an easy-to-open flip cap, which is user-friendly, especially for those with limited hand dexterity.

Additionally, the gel is paraben and dye-free, non-greasy, and has a clean scent, making it more comfortable to use regularly without unpleasant residue or strong odors. However, there are some drawbacks. The need to apply the gel four times a day might be inconvenient for some users. Also, it is limited to treating only up to two joints simultaneously. While it is a strong alternative to oral pills, it might not work equally well for everyone, and some might still prefer the convenience of a single-dose pill. Despite these minor inconveniences, the Voltaren Arthritis Pain Gel offers a powerful and targeted approach to managing arthritis pain effectively.

Biofreeze Professional Gel is a popular choice for those seeking relief from arthritis pain, muscle soreness, and joint discomfort. The active ingredient, menthol, is known for its cooling effect and fast-acting relief, which is particularly beneficial for managing arthritis pain. The gel form and the 32 fl oz bottle with a pump make it convenient for application on both small and large areas, such as knees and the lower back. This product is also well-regarded by professionals, including pharmacists, physical therapists, and chiropractors, adding credibility to its effectiveness.

Additionally, it's HSA/FSA eligible, potentially allowing users to save on costs. On the plus side, the gel is colorless, which means it won't stain clothing, and it’s made without NSAIDs, reducing the risk of certain side effects. However, some users may find the menthol scent to be strong, which could be a drawback for those sensitive to strong smells. The gel's absorption rate is typically fast, but people with sensitive skin should test a small area first to ensure there’s no irritation. The duration of relief varies, but many users report long-lasting effects.

It's also worth noting that the product has not been tested on animals, which is a significant plus for ethically-conscious consumers. This product is best suited for individuals seeking targeted, effective, and fast-acting pain relief for arthritis and muscle soreness.