10 Best Bug Sprays Safe For Pets 2025 in the United States

Ortho Home Defense Max Bed Bug, Flea and Tick Killer is designed to tackle tough pests like bed bugs, fleas, and ticks effectively. It comes in a 1-gallon spray form and includes a Comfort Wand, which makes it easier to apply the spray precisely in hard-to-reach places such as mattress seams and baseboards. This is especially helpful because bed bugs often hide in tight spots. The spray is known to kill even resistant bed bugs, which many similar products struggle with.

The scent is described as 'Tick,' which might be noticeable and could be a downside if you’re sensitive to smells. Since it’s a chemical spray, pet owners should be cautious and follow instructions carefully to ensure pets are not exposed during and immediately after use.

This product is suited for people dealing with persistent indoor pest problems seeking a strong, targeted solution, though those who prioritize natural ingredients or guaranteed pet safety might want to consider these factors before purchasing.

The Wondercide Flea, Tick & Mosquito Spray is a natural, plant-based spray designed to protect pets and homes from fleas, ticks, and mosquitoes. This 16 oz spray, featuring cedarwood oil as the active ingredient, is safe for use on dogs and cats of all ages, making it a versatile choice for multi-pet households. It effectively kills and repels pests on contact, breaking the flea life cycle by targeting eggs, larvae, and adults.

This is a significant strength as it offers comprehensive pest control without the need for harsh chemicals. The convenient spray application method allows for easy use on pets, as well as on household surfaces like carpets, furniture, and bedding. Additionally, the lemongrass scent is a pleasant touch that freshens up your home while keeping pests at bay. However, some users might find the scent too strong, and it's important to test a small area on your pet before full application to ensure there are no adverse reactions.

The product is cruelty-free and made in the USA, which adds to its appeal for ethically-conscious consumers. While it provides a safe alternative to traditional pest control methods, it may require more frequent application to maintain its effectiveness, which could be seen as a drawback for those looking for a longer-lasting solution.

The Wondercide Ready to Use Flea, Tick, and Mosquito Yard Spray is a plant-based product designed to protect your yard from pests while keeping your pets and family safe. It uses natural essential oils, particularly cedarwood oil, to effectively kill and repel fleas, ticks, and mosquitoes. The pre-mixed formula is easy to use; simply attach it to a garden hose, spray your yard, and you can immediately re-enter the treated area without waiting for it to dry, which is convenient for busy households with pets and kids.

This spray can cover up to 5,000 square feet for fleas and mosquitoes and 2,500 square feet for ticks, making it suitable for medium to large yards. Additionally, it's made in the USA, free from artificial colors, dyes, and fragrances, and it's safe for beneficial insects like bees and butterflies when used as directed.

On the downside, the effectiveness can vary depending on water pressure and walking speed during application. Furthermore, while it has a pleasant cedar scent, some users might find it stronger than expected. As with any pest control product, following the usage directions carefully is essential to ensure safety and efficacy.