10 Best Calming Products For Cats 2026 in the United States

The TherapetMD Cat Calming Diffuser is a plug-in pheromone diffuser designed to reduce anxiety and stress in cats, especially in multi-cat households. It uses a natural, vet-recommended dual-pheromone formula that mimics facial and maternal cat pheromones, helping to significantly cut down behaviors like urine spraying and scratching. One of its strengths is the 700 sq ft coverage area, making it suitable for larger rooms or shared spaces.

The diffuser works continuously once plugged in, with each refill lasting about 30 days, so it’s convenient and requires minimal effort from owners. It’s fragrance-free and safe for cats, humans, and other pets, which is important for households with multiple animals or sensitive individuals. Many users report noticeable improvements in reducing hiding, fear, and tension between cats, making it helpful during stressful events like vet visits or introducing new pets. It may take a few days to see the calming effects, and the low-glow indicator light might be hard to notice in bright settings, though this doesn’t affect the diffuser’s function.

Some cats may respond differently depending on their individual preferences, so results can vary. This diffuser provides a gentle, chemical-free way to create a calmer environment for anxious or stressed cats without hassle, although patience is needed to observe the full benefits.

The FELIWAY Optimum Enhanced Calming Pheromone is a 30-day refill designed to reduce stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. As a non-sedating and drug-free solution, it releases pheromone analogs to provide a natural, reassuring message to cats, helping them feel more at ease. This product is easy to use—simply plug the diffuser into an open outlet with good air circulation, and it will work continuously for up to 30 days.

It’s important to use the FELIWAY diffuser with its specific refills for optimal results. One diffuser covers up to 700 square feet, and it should be replaced every six months, with refills changed monthly. Backed by over 25 years of research and recommended by vets, it’s a reliable choice for many cat owners.

However, it may not be universally effective for all cats, and the need to replace refills and diffusers regularly could be a recurring cost. Additionally, while it is safe for cats, humans, and other pets, it carries a specific scent (Mimosa) that may not appeal to everyone. This product is most beneficial for cat owners dealing with noticeable signs of feline stress in their homes.

The Vetoquinol Zylkene Calming Supplement is designed to help small dogs and cats manage stress from situations like travel, vet visits, or loud noises. Its main calming ingredient, alpha-casozepine, comes from a milk protein, making it a natural option that avoids drowsiness or harsh side effects commonly seen in other calming products.

This supplement is lactose-free and gentle on sensitive stomachs, which is beneficial for cats with digestive sensitivities. The package contains capsules that you open and sprinkle over your pet’s food, making it straightforward to use daily. This daily routine can support behavioral issues and help your cat stay calm during stressful events.

With a solid positive rating from many users, Zylkene offers a safe, gentle, and easy-to-administer way to support your cat’s relaxation. Pet owners should monitor their cat’s response and ensure proper dosing.