10 Best Calming Products For Cats 2025 in the United States

The Vetoquinol Zylkene Calming Supplement is designed to help small dogs and cats manage stress from situations like travel, vet visits, or loud noises. Its main calming ingredient, alpha-casozepine, comes from a milk protein, making it a natural option that avoids drowsiness or harsh side effects commonly seen in other calming products.

This supplement is lactose-free and gentle on sensitive stomachs, which is beneficial for cats with digestive sensitivities. The package contains capsules that you open and sprinkle over your pet’s food, making it straightforward to use daily. This daily routine can support behavioral issues and help your cat stay calm during stressful events.

With a solid positive rating from many users, Zylkene offers a safe, gentle, and easy-to-administer way to support your cat’s relaxation. Pet owners should monitor their cat’s response and ensure proper dosing.

The FELIWAY Optimum Enhanced Calming Pheromone is a 30-day refill designed to reduce stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. As a non-sedating and drug-free solution, it releases pheromone analogs to provide a natural, reassuring message to cats, helping them feel more at ease. This product is easy to use—simply plug the diffuser into an open outlet with good air circulation, and it will work continuously for up to 30 days.

It’s important to use the FELIWAY diffuser with its specific refills for optimal results. One diffuser covers up to 700 square feet, and it should be replaced every six months, with refills changed monthly. Backed by over 25 years of research and recommended by vets, it’s a reliable choice for many cat owners.

However, it may not be universally effective for all cats, and the need to replace refills and diffusers regularly could be a recurring cost. Additionally, while it is safe for cats, humans, and other pets, it carries a specific scent (Mimosa) that may not appeal to everyone. This product is most beneficial for cat owners dealing with noticeable signs of feline stress in their homes.

Pet Honesty Calming Chews for Cats are designed as tasty, easy-to-give treats that help reduce anxiety and promote relaxation in cats, especially during stressful events like travel, vet visits, or separation. They feature natural calming ingredients such as L-Theanine, L-Tryptophan, Chamomile, and Thiamine (Vitamin B1), which support the nervous system and help soothe anxious behavior. The chews come in a crunchy and creamy chicken flavor that many cats find appealing, making administration less challenging.

These chews are intended for all ages and medium breeds, with dosage based on the cat's weight, and can be given daily to maintain a calming effect over time. The product is made in the USA under strict safety standards, free from common allergens like corn, wheat, and soy, and contains no artificial additives, which supports its safety profile. The duration of the calming effect can vary between cats, and some cats might not respond to supplements as expected.

The product is well-rated by many users, although individual preferences for taste and texture may differ, so it might require some trial and error. This makes these chews a natural, convenient option for cat owners seeking to ease their pet’s stress with minimal fuss, especially if their cat enjoys flavored treats and needs support in mildly stressful situations.