10 Best Carry On Backpacks 2025 in the United States

The Peak Design Travel Backpack 45L is a versatile option for travelers needing a carry-on backpack that adjusts to different trip lengths. Its expandable design lets you switch between 35 and 45 liters of space, which is handy for packing light or bringing extra gear. At around 4.5 pounds, it strikes a good balance—not too heavy to carry long but still feeling sturdy. Comfort-wise, it includes padded shoulder straps and a hip belt that can be tucked away for a sleeker look, helping distribute weight during longer carries.

The backpack’s weatherproof 400D recycled nylon shell and solid zippers make it durable enough to handle rough travel conditions without looking bulky. It provides easy access through the top, rear, and sides, so you can grab items quickly without unpacking everything. Organizational features include a laptop sleeve and expandable side pockets for water bottles or tripods, which helps keep items organized and accessible.

Some may find the pack’s 22 x 9 x 13 inch dimensions a bit large for very strict carry-on limits depending on the airline, so it’s good to double-check that. Also, since it’s made with durable materials, it’s not the lightest backpack available, so if ultra-lightweight is your priority, this might feel a bit heavy. Cleaning requires spot treatment, as machine washing is not recommended. This backpack is well suited for frequent travelers who want a tough, adaptable bag with smart organization and weather resistance that can handle both daily use and longer trips.

The Osprey Fairview 36L Women's Wheeled Travel Backpack is a versatile choice for travelers who want the option to wheel their luggage or carry it comfortably on their back. It fits within domestic carry-on size limits and offers a moderate 36-liter capacity, suitable for short trips or minimalist packing. Weighing about 5.3 pounds, it strikes a reasonable balance between sturdiness and portability, though it’s a bit heavier than some lighter backpacks.

Comfort is a highlight here, thanks to padded shoulder straps, a hipbelt, and a tensioned mesh back panel that can be stowed away when not needed. This makes it easier to carry for longer periods when wheels aren’t practical, such as on stairs or rough terrain. The materials used are durable, designed to handle travel wear and tear, which adds to its long-lasting appeal.

Organizationally, it’s not overly complex, with two main compartments and webbing straps on the front to attach smaller compatible packs if needed, keeping things straightforward and user-friendly. Those needing many pockets or specialized compartments might find it somewhat limited. This backpack is well suited for female travelers who want a reliable, flexible carry-on option that can switch between wheeled and backpack modes without hassle, though heavier packing or extensive organization needs might require additional solutions.

The MATEIN 45L Travel Backpack is a solid choice for travelers looking for a large, versatile carry-on bag. With its expandable design, it comfortably meets airline carry-on size rules while offering extra space when you need it. Weighing just over 2 pounds, it’s lightweight enough to carry without feeling too bulky. Comfort is addressed through adjustable shoulder straps, a ventilated back panel, and a sternum strap that helps spread the weight evenly across your chest.

The backpack’s convertible style, allowing you to hide the shoulder straps and carry it like a briefcase, adds flexibility for different travel situations. Organization-wise, it includes compartments for essentials like phones and headphones, plus internal compression straps to keep your items secure and neat. It also features four external compression straps that help stabilize the load and protect the zippers. Durability is a strong point thanks to water-resistant polyester, sturdy zippers, and solid stitching, ensuring it can handle various travel conditions.

The relatively large size might be a bit much if you prefer a more compact backpack. Also, while it has many useful features for travelers, those seeking specialized compartments for tech gear or hiking might find it basic. This backpack is well suited for weekend and business travelers who want a reliable, roomy, and comfortable carry-on option with good durability and organization.