10 Best Carry On Backpacks 2025 in the United States

The Osprey Fairview 36L Women's Wheeled Travel Backpack is a versatile choice for travelers who want the option to wheel their luggage or carry it comfortably on their back. It fits within domestic carry-on size limits and offers a moderate 36-liter capacity, suitable for short trips or minimalist packing. Weighing about 5.3 pounds, it strikes a reasonable balance between sturdiness and portability, though it’s a bit heavier than some lighter backpacks.

Comfort is a highlight here, thanks to padded shoulder straps, a hipbelt, and a tensioned mesh back panel that can be stowed away when not needed. This makes it easier to carry for longer periods when wheels aren’t practical, such as on stairs or rough terrain. The materials used are durable, designed to handle travel wear and tear, which adds to its long-lasting appeal.

Organizationally, it’s not overly complex, with two main compartments and webbing straps on the front to attach smaller compatible packs if needed, keeping things straightforward and user-friendly. Those needing many pockets or specialized compartments might find it somewhat limited. This backpack is well suited for female travelers who want a reliable, flexible carry-on option that can switch between wheeled and backpack modes without hassle, though heavier packing or extensive organization needs might require additional solutions.

The TUMI Alpha Bravo International 2 Wheeled Duffel Backpack Carry-On is a versatile travel bag designed for convenience. Its standout feature is the combination of a backpack and duffel bag with wheels, making it adaptable to various travel situations. The size, at 21.8 x 14.0 x 9.0 inches, provides a substantial 40-liter capacity, ideal for short to medium-length trips. It's crafted from durable, weather-resistant ballistic nylon, ensuring that it can withstand the rigors of frequent travel while keeping your belongings secure.

Organizational features include interior tie-down straps and two zipper pockets, enhancing its practicality by keeping items organized and easily accessible. The weight, at 7.1 pounds, might be on the heavier side for a carry-on backpack, which could be a drawback for those prioritizing lightweight gear. Comfort-wise, its multiple carrying options—including wheels and backpack straps—offer flexibility, though it may not be as comfortable as dedicated backpacks when carried for extended periods.

Additionally, handy travel-smart features like a TSA-friendly lock and the TUMI Tracer add extra layers of convenience and security. This backpack is particularly suitable for travelers who value durability and versatility, but the weight and potentially higher price point could be deterrents for others.

The MATEIN 45L Travel Backpack is a solid choice for travelers looking for a large, versatile carry-on bag. With its expandable design, it comfortably meets airline carry-on size rules while offering extra space when you need it. Weighing just over 2 pounds, it’s lightweight enough to carry without feeling too bulky. Comfort is addressed through adjustable shoulder straps, a ventilated back panel, and a sternum strap that helps spread the weight evenly across your chest.

The backpack’s convertible style, allowing you to hide the shoulder straps and carry it like a briefcase, adds flexibility for different travel situations. Organization-wise, it includes compartments for essentials like phones and headphones, plus internal compression straps to keep your items secure and neat. It also features four external compression straps that help stabilize the load and protect the zippers. Durability is a strong point thanks to water-resistant polyester, sturdy zippers, and solid stitching, ensuring it can handle various travel conditions.

The relatively large size might be a bit much if you prefer a more compact backpack. Also, while it has many useful features for travelers, those seeking specialized compartments for tech gear or hiking might find it basic. This backpack is well suited for weekend and business travelers who want a reliable, roomy, and comfortable carry-on option with good durability and organization.