10 Best Cat Probiotics 2026 in the United States

Zesty Paws Probiotics for Cats is a powder supplement designed to support your cat's digestive health and immune system. It features the DE111 strain, a clinically studied type of Bacillus subtilis, which is good for balancing gut bacteria and promoting healthy digestion. Each serving offers 800 million CFUs, which is a moderate amount that can benefit most cats without overwhelming their system. The powder is easy to mix into your cat's wet or dry food and has a pumpkin flavor that many cats find appealing, making it simpler to give daily. The formulation also includes inulin, a fiber that helps digestion, and yeast extract, which may enhance the probiotic benefits and immune support.

The product contains only one primary probiotic strain, so it might not provide the variety of strains some other supplements offer. While it is shelf-stable and convenient for regular use, those looking for a broader strain diversity might want to consider other options. This probiotic is a good choice for cat owners wanting an easy-to-administer, pumpkin-flavored powder that combines probiotics with helpful fibers to aid digestion and immunity, especially for indoor house cats.

Purina Pro Plan Veterinary Supplements FortiFlora Cat Probiotic Supplement is designed to support digestive health in cats experiencing diarrhea. It is highly recommended by veterinarians, which speaks to its efficacy. The supplement contains the active probiotic strain Enterococcus Faecium SF68, known for promoting intestinal health and balance.

The formulation is easy to administer as it comes in a powder form that can be mixed with food, making it convenient for cat owners. Additionally, the inclusion of antioxidants helps support the cat's immune system, which is a valuable benefit beyond digestive health.

The product is suitable for cats of all ages, starting from one month old. FortiFlora offers a reliable solution for managing digestive issues in cats with the added benefit of immune support.

Pet Honesty Cat Probiotics Gut + Immune Health Chews are designed to support your cat's digestive and immune health. These chews come in a convenient and tasty chicken flavor that most cats seem to enjoy. They include probiotics that help maintain healthy gut flora, prebiotics to promote beneficial bacteria, and omegas for a robust immune system.

The chews are formulated without corn, wheat, soy, or artificial preservatives, colors, and flavors, making them a good choice for health-conscious pet owners. Made in the USA, these supplements meet high safety and quality standards as Pet Honesty is a NASC member company.

Ideal for adult cats, they offer a 30-day supply aimed at improving gut health, immunity, and regularity, while also providing relief from constipation.