10 Best Cat Probiotics 2026 in the United States

Zesty Paws Probiotics for Cats is a powder supplement designed to support your cat's digestive health and immune system. It features the DE111 strain, a clinically studied type of Bacillus subtilis, which is good for balancing gut bacteria and promoting healthy digestion. Each serving offers 800 million CFUs, which is a moderate amount that can benefit most cats without overwhelming their system. The powder is easy to mix into your cat's wet or dry food and has a pumpkin flavor that many cats find appealing, making it simpler to give daily. The formulation also includes inulin, a fiber that helps digestion, and yeast extract, which may enhance the probiotic benefits and immune support.

The product contains only one primary probiotic strain, so it might not provide the variety of strains some other supplements offer. While it is shelf-stable and convenient for regular use, those looking for a broader strain diversity might want to consider other options. This probiotic is a good choice for cat owners wanting an easy-to-administer, pumpkin-flavored powder that combines probiotics with helpful fibers to aid digestion and immunity, especially for indoor house cats.

Zesty Paws Probiotic Bites are soft chews designed specifically to support your cat's digestive and immune health. They contain two strains of live probiotic bacteria, including a clinically studied strain called DE111 (Bacillus subtilis), which is known for its gut and immune benefits. With 600 million CFUs per chew, these supplements provide a moderate amount of good bacteria to help balance your cat's intestinal flora. The bites also include a prebiotic fiber, fructooligosaccharides (FOS), which helps feed the good bacteria already in your cat’s gut, promoting a healthier digestive environment.

The chicken flavor makes these treats more appealing and easier to give, especially if your cat is picky. Since they come in soft chew form, they are convenient and do not require mixing into food. The probiotic strain diversity is limited to just two strains, which is fewer than some other options that may offer a broader mix for potentially more comprehensive gut support. Shelf stability seems reliable for typical pet supplement use, though specific storage details are not emphasized.

Zesty Paws offers a tasty, easy-to-administer option for house cats needing regular probiotic support, and those seeking a formula with a wider variety of probiotic strains might consider other products.

Purina Pro Plan Veterinary Supplements FortiFlora Cat Probiotic Supplement is designed to support digestive health in cats experiencing diarrhea. It is highly recommended by veterinarians, which speaks to its efficacy. The supplement contains the active probiotic strain Enterococcus Faecium SF68, known for promoting intestinal health and balance.

The formulation is easy to administer as it comes in a powder form that can be mixed with food, making it convenient for cat owners. Additionally, the inclusion of antioxidants helps support the cat's immune system, which is a valuable benefit beyond digestive health.

The product is suitable for cats of all ages, starting from one month old. FortiFlora offers a reliable solution for managing digestive issues in cats with the added benefit of immune support.