10 Best Digestive Enzymes 2025 in the United States

Zenwise Health Digestive Enzymes are designed to support digestive health for both men and women. They combine a unique blend of plant-based enzymes, probiotics, and prebiotics, making them a solid option for anyone looking to enhance their digestion and reduce bloating. One key strength of this product is its 3-in-1 formula, which targets the breakdown of proteins, fats, and carbohydrates. This can lead to more efficient nutrient absorption and may help alleviate discomfort from indigestion. Users will appreciate the quick action of these enzymes, promising noticeable relief from digestive issues soon after consumption.

Another advantage is the inclusion of proven probiotics that reach the small intestine alive, which is crucial for effective nutrient absorption. Those who suffer from gas and bloating may find additional relief thanks to the targeted enzymes that work to soothe these common issues.

On the downside, while the product is vegetarian and utilizes plant-based ingredients, some users might prefer a broader range of enzyme types or higher enzyme activity levels. Additionally, results can vary based on individual digestive systems—some may experience significant benefits while others may find it less effective. The capsule form, while convenient, may not be suitable for everyone, especially those who prefer chewable or liquid options.

The Physician's CHOICE Advanced Gut Health Bundle combines a strong 60 billion CFU probiotic with digestive enzymes in an easy-to-take capsule form, designed to support digestive, gut, and immune health. This bundle targets common digestive problems such as occasional constipation, diarrhea, gas, and bloating, making it a solid option for those experiencing general digestive discomfort.

The included digestive enzymes help your body break down food more efficiently, which can improve nutrient absorption—a key factor if you want to get the most from your diet. The probiotic’s ability to survive the digestive tract helps beneficial bacteria establish themselves in your gut for longer-lasting effects.

By combining two popular supplements, this bundle offers convenience and value, potentially saving you money compared to buying each separately. For those wanting a general digestive aid with both probiotics and enzymes in one package, this bundle is a practical and approachable choice.

The Garden of Life Vegetarian Digestive Supplement - Omega Zyme Ultra Enzyme Blend is designed to support digestive health comprehensively. It boasts a robust formula containing 21 different digestive enzymes, which can play a significant role in breaking down a wide range of foods, aiding in digestion, and addressing issues like bloating, gas, and IBS. This broad-spectrum enzyme activity is optimized across the varying pH levels of the gastrointestinal tract, which can be beneficial for thorough digestion throughout the entire digestive system.

The inclusion of plant-based and ocean-based trace minerals may further enhance its nutritional value. The vegetarian capsules dissolve quickly for rapid nutrient release, which is particularly advantageous for those seeking quick relief and support. The product is also gluten-free, dairy-free, and free from artificial colors and preservatives, making it suitable for individuals with specific dietary restrictions or sensitivities. However, it should be noted that at 180 capsules per bottle, the dosage may vary based on individual needs, and consulting with a healthcare professional is recommended to determine the suitable intake.

The fact that it is unflavored is a plus for those who prefer no added flavors, but it might be less appealing to those who prefer some taste in their supplements. Made in the U.S.A., this product aligns well with those who prioritize locally manufactured health products. The Garden of Life Omega Zyme Ultra Enzyme Blend is a strong contender for anyone seeking comprehensive digestive enzyme support, particularly adults who suffer from digestive discomforts.