10 Best Dog Toothpaste For Gum Disease 2025 in the United States

The Virbac C.E.T. Enzymatic Toothpaste is formulated for both dogs and cats, making it versatile for pet owners with multiple animals. It uses an enzyme system specifically designed to reduce plaque and freshen breath, which is crucial for pets suffering from gum disease. The toothpaste comes in a Vanilla Mint flavor, which is a refreshing change from typical poultry or beef flavors and is likely to be enjoyed by pets. It's safe for daily use, as it includes no foaming agents, meaning it is safe for pets to swallow, which is a significant advantage for pet owners concerned about their pets ingesting toothpaste. Additionally, it is paraben-free, which is a plus for those looking for a more natural option.

The product's veterinary approval and the brand's reputation, being the top recommended dental brand by professionals, add further credibility and assurance to its effectiveness. However, it should be noted that it still requires the use of a toothbrush, which might be a bit challenging for some pet owners to manage regularly, especially if their pets are not accustomed to having their teeth brushed. The 2.5 oz tube size is modest, meaning you might need to purchase it frequently if used daily. This product is best suited for pet owners who are diligent about their pet's dental hygiene and can incorporate daily brushing into their routine. For others, it might require some adjustment and patience to get their pets used to the process.

Vet’s Best Enzymatic Dog Toothpaste is designed to help support your dog's dental hygiene and is particularly suitable for addressing gum disease. The toothpaste features a veterinarian-formulated blend of natural ingredients like aloe, neem oil, and grapefruit seed extract, which aim to soothe and effectively clean your dog's teeth. The enzymatic formula helps break down plaque and tartar, which is essential for treating gum disease and maintaining overall dental health.

This product is banana flavored, which most dogs find appealing, making the brushing process easier for pet owners. The consistency is described as a gel, which can be applied with a brush or your finger, adding to its versatility and ease of use. However, it's important to note that dogs should not eat or drink for half an hour before and after application for the best results.

While the toothpaste is paraben-free and comes in an easy-to-use squeeze tube, some pet owners may prefer a different flavor or might find the application frequency (2-3 times per week) challenging to maintain. Despite these minor drawbacks, Vet’s Best Enzymatic Dog Toothpaste is a strong contender for those seeking an effective and vet-approved option for their dog's dental care routine.

Petsmile Professional Pet Toothpaste stands out as a reliable choice for improving your dog's oral health, especially if you're concerned about gum disease. It is the only pet toothpaste approved by the Veterinary Oral Health Council (VOHC), showing it meets high veterinary standards. The toothpaste uses a special enzymatic formula called Calprox that helps reduce plaque, tartar, and gingivitis by gently breaking down the proteins on your dog's teeth. This not only cleans and whitens teeth but also promotes healthier gums and fresher breath.

One of its biggest advantages is the use of human-grade, safe ingredients, meaning it’s non-toxic and your pet can eat or drink right after use without worry. Its London Broil flavor is designed to be appealing, making it easier to get even picky pets to accept. Another helpful feature is that it doesn’t require brushing—simply apply the paste and let your dog’s tongue do the work, which is great if your dog dislikes brushing. The consistency is a paste, which spreads easily across teeth.

Some pet owners might prefer a brushing toothpaste for deeper cleaning, as the no-brush formula relies on your pet's cooperation and natural licking. Also, while the flavor is unique and generally well-liked, some dogs might take time to adjust. Petsmile is a strong option for dog owners seeking a vet-approved, easy-to-use toothpaste that supports gum health and plaque control without harsh chemicals.