10 Best Enzyme Cleaner For Cat Pee 2025 in the United States

Rocco & Roxie Supply Co. Stain & Odor Eliminator is a strong contender in the enzyme cleaner category for cat pee. One of its primary strengths is its enzyme-activated formula, which works by breaking down ammonia crystals and organic matter, ensuring thorough elimination of stains and odors. This is particularly beneficial for dealing with tough cat urine stains and smells.

The product is also versatile, suitable for use on various surfaces including carpets, floors, furniture, and even clothing. This makes it a convenient choice for pet owners who need a multipurpose cleaner. Additionally, it is certified gentle and safe, being chlorine-free and color-safe, which means it can be used around pets and children without worry. Its approval by the Carpet and Rug Institute further underscores its safety and effectiveness on carpets.

Potential buyers will also need to ensure they purchase from authorized retailers to benefit from the satisfaction guarantee. This cleaner is ideal for pet owners who frequently deal with pet stains and odors, particularly those with cats or small animals.

Rocco & Roxie Extreme Stain & Odor Eliminator is a versatile enzyme cleaner designed to tackle tough pet stains and odors, including cat pee. It combines a potent bio-enzymatic formula with a mineral-based odor neutralizer to effectively eliminate ammonia crystals and organic matter. The cleaner is suitable for various surfaces like carpets, floors, furniture, clothing, and pet bedding, making it a handy tool for pet owners.

Its subtle Meyer lemon scent ensures a fresh environment without being overpowering and it dries reasonably fast after application. Additionally, the product is chlorine-free, color-safe, and certified safe for use around pets and children, receiving the Carpet and Rug Institute's Seal of Approval. This shows its gentle nature while still being effective.

While its eco-friendliness stems from being chlorine-free and using no hazardous propellants, some users might prefer a product with explicit eco-certifications. The return and satisfaction policies are clear, offering peace of mind for buyers. However, it's essential to purchase from authorized retailers to benefit from these guarantees. This product is highly effective for removing tough pet stains and odors, making it ideal for households with pets, particularly those dealing with frequent accidents.

Angry Orange Stain Remover is a 32oz enzyme pet cleaner designed to tackle dog and cat urine, among other pet messes. One of its standout features is the dual-action formula, which not only removes stains but also eliminates odors, offering up to 80 hours of freshness. The product is versatile in its application, suitable for multiple surfaces such as carpets, hardwood floors, fabrics, and even turf, making it a practical choice for households with pets who roam freely across different areas.

It is easy to use, provided in a spray form, which allows for direct application on the affected areas. The citrus scent, derived from natural enzymes and cold-pressed orange oils, leaves a pleasing aroma, although some users might find it less desirable if they prefer an unscented cleaner. While the product is natural and safe for homes with pets and children, it should not be sprayed directly onto them.

Manufactured by Genesis BioSciences, Inc. and available since 2019, this cleaner has garnered a place in the Best Sellers rank in the Pet Supplies category. Angry Orange Stain Remover offers a strong combination of effectiveness, versatility, and pleasant scent, although potential buyers should be aware of the citrus fragrance.