10 Best Enzyme Cleaner For Cat Pee 2025 in the United States

Rocco & Roxie Extreme Stain & Odor Eliminator is a versatile enzyme cleaner designed to tackle tough pet stains and odors, including cat pee. It combines a potent bio-enzymatic formula with a mineral-based odor neutralizer to effectively eliminate ammonia crystals and organic matter. The cleaner is suitable for various surfaces like carpets, floors, furniture, clothing, and pet bedding, making it a handy tool for pet owners.

Its subtle Meyer lemon scent ensures a fresh environment without being overpowering and it dries reasonably fast after application. Additionally, the product is chlorine-free, color-safe, and certified safe for use around pets and children, receiving the Carpet and Rug Institute's Seal of Approval. This shows its gentle nature while still being effective.

While its eco-friendliness stems from being chlorine-free and using no hazardous propellants, some users might prefer a product with explicit eco-certifications. The return and satisfaction policies are clear, offering peace of mind for buyers. However, it's essential to purchase from authorized retailers to benefit from these guarantees. This product is highly effective for removing tough pet stains and odors, making it ideal for households with pets, particularly those dealing with frequent accidents.

The Rocco & Roxie Stain & Odor Eliminator is an enzyme cleaner designed specifically to tackle tough pet odors, including cat urine. It uses natural enzymes that activate when sprayed, breaking down urine and organic stains at their source rather than just masking the smell. The product is safe for use around pets and children, as it is free from chlorine and harsh chemicals. It is also certified safe for all carpet types, helping to avoid damage to flooring.

This cleaner is versatile and can be used on a variety of surfaces beyond carpet, such as furniture, floors, clothing, and pet bedding, making it suitable for many household messes. The scent is described as “original,” indicating a mild, non-overpowering smell that is unlikely to be unpleasant once dry. The product is eco-friendly, relying on natural enzymes and no harmful propellants, making it a more environmentally conscious choice compared to chemical cleaners.

The bottle size is 32 ounces, which is moderate; users with multiple pets or large areas to treat might need to replenish more frequently. Rocco & Roxie Stain & Odor Eliminator is a reliable, safe, and natural enzyme cleaner for cat urine and other organic stains around the home.

The Bioda Multi-Purpose Probiotic Enzyme Cleaner is a strong option if you need a versatile and natural solution for cleaning pet stains like cat pee. Unlike some cleaners that just mask odors, this one uses probiotic enzymes that keep working for up to 21 days, breaking down the organic mess at its source. It's easy to use—just spray it on—and it works on many surfaces including floors, carpets, drains, bathrooms, and trash bins, making it a handy all-in-one cleaner.

The scent is a fresh lemon and sage mix, which is light and pleasant, so it won’t leave a harsh chemical smell behind. Because it’s probiotic and natural, it’s eco-friendly and avoids harmful chemicals, which is great if you want a safer cleaning option around pets and kids. It comes in a large 1-gallon bottle, which is cost-effective but might be bulky if you only need it for small areas.

If you’re looking for a professional-strength cleaner that tackles tough organic odors and stains naturally, this Bioda enzyme cleaner fits the bill well.