10 Best Fire Ant Killing 2025 in the United States

The Ortho Fire Ant Killer Broadcast Granules are designed to protect lawns from fire ants by targeting fly-in queens to prevent new mounds from forming. The granule formulation is easy to apply using a spreader and requires watering in, which fits well for homeowners looking for a straightforward lawn treatment. One of its biggest benefits is fast action—killing mounds within 15 minutes—and providing up to 6 months of protection across a large area (5,000 sq. ft.) with just one 11.5 lb. bag.

This product works best as part of a two-step system where an initial mound treatment (using a different Ortho product) is recommended to destroy existing colonies. This means it might not be the sole solution if you already have many active fire ant mounds. The granule form is generally safer for outdoor use around pets and children compared to liquid sprays, but it's always important to follow label instructions closely for safety. If you want a long-lasting, easy-to-use broadcast treatment that keeps fire ants at bay after initial mound control, this is a solid choice. Just keep in mind it won’t replace direct mound treatment for existing infestations.

The Ortho Orthene Fire Ant Killer1 is designed to effectively target and eliminate fire ants, particularly by killing the queen and destroying the mound. It contains Acephate as its active ingredient, which is known for its potency against fire ants. The product comes in granule form, making it easy to sprinkle directly onto mounds without the need for additional watering, which simplifies the application process.

This fire ant killer begins working within 60 minutes, providing quick results and allowing users to enjoy their outdoor spaces sooner. Each pack includes two 12 oz. bottles, capable of treating up to 162 mounds, making it a cost-effective solution for large infestations. However, it's important to note that while the product is effective outdoors around lawns, ornamental plants, and trees, users should exercise caution regarding its safety for pets and children, as the active ingredient, Acephate, can be toxic if ingested or improperly handled.

Additionally, for optimum results, it is recommended to use this product in conjunction with Ortho Fire Ant Killer Broadcast Granules, which are sold separately. This might be seen as a drawback for those looking for a one-step solution.

The Ortho Orthene Fire Ant Killer is a powder-based product designed to quickly eliminate fire ant mounds by targeting the queen ant, which is crucial for stopping the colony from returning. It can treat up to 189 mounds, making it suitable for larger yard areas. One of its main benefits is how fast it works—it starts killing ants within 60 minutes, letting you enjoy your outdoor space again quickly. Application is simple: just sprinkle the powder over each mound following the product instructions. It’s safe to use around lawn areas and ornamental plants like flowers and shrubs, which is convenient for most home gardens.

This product effectively kills existing colonies and works best when combined with Ortho’s broadcast granules (sold separately), which help prevent new mounds from forming for up to six months. This two-step system provides longer-term control rather than just a one-time treatment.

This fire ant killer is a strong choice if you need a fast-acting, easy-to-use solution for multiple fire ant mounds and don’t mind purchasing a second product for ongoing protection. Users should take standard precautions when applying the product outdoors.