We Use CookiesWe use cookies to enhance the security, performance, functionality and for analytical and promotional activities. By continuing to browse this site you are agreeing to our privacy policy

10 Best Hot Spot Spray For Dogs 2025 in the United States

How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

headphones-stars

Our Top Picks

#1

Winner

Restore + Soothe Hot Spots Spray for Dogs & Cats - Gentle on Sensitive Skin, Chlorhexidine Alternative Spray, Soothes Itching, Irritation with Aloe and Microsilver (Lavender) - 4oz

Rating
10.0
Chosen by1,275
Antimicrobial Properties
Scent
Skin Type Compatibility

Most important from
12023 reviews

Antimicrobial Properties
Highly recommended by a professional groomer for its outstanding and affordable medicated properties. Works as well as vet-prescribed shampoos for half the price.
Scent
It helps with shedding and acts as a deodorizing shampoo, keeping pets smelling great between baths.
Skin Type Compatibility
Effective and soothing, a must-have for pet care! This product has made a noticeable difference in addressing various skin issues, including allergies, itching, and hot spots.

Pet Honesty Restore + Soothe Hot Spots Spray is a natural solution designed to provide fast relief for dogs with itchy hot spots. Infused with ingredients like aloe and chamomile, it aims to soothe irritated skin quickly. The presence of MicroSilver BG, a clinically studied component, enhances its ability to relieve itching and odor for up to 7 days. This makes it a good alternative to sprays containing Chlorhexidine for pet owners looking for a more natural treatment option.

The spray is also free from sulfates, parabens, phthalates, and artificial dyes, making it friendly for sensitive skin and reducing the risk of further irritation. The lavender scent is pleasant and helps neutralize odors, but it might not be suitable for pets or owners sensitive to fragrances. Application is straightforward, but the drying time can be variable, which might require pet owners to monitor their pets to avoid them licking the product off too soon.

The product's size (4oz) is convenient for frequent use and easy to handle. However, users might find it a bit pricey compared to other options, considering the small bottle size. This product is best suited for pet owners looking for a natural, vet-recommended remedy for their pet’s skin issues, particularly those with sensitive skin, who are willing to invest in a premium product.

Rating
10.0
Chosen by1,275
Antimicrobial Properties
Scent
Skin Type Compatibility

Most important from
12023 reviews

Antimicrobial Properties
Highly recommended by a professional groomer for its outstanding and affordable medicated properties. Works as well as vet-prescribed shampoos for half the price.
Scent
It helps with shedding and acts as a deodorizing shampoo, keeping pets smelling great between baths.
Skin Type Compatibility
Effective and soothing, a must-have for pet care! This product has made a noticeable difference in addressing various skin issues, including allergies, itching, and hot spots.
#2

HICC PET Dog Hot Spot Treatment Spray, Itch Relief for Dog Care& Cat Care, 2X Strength for Dog Wound Care, Alleviate Dry Itchy Skin, Allergies, Inflammation, Dog Skin Irritation Treatment, 10 fl oz

Rating
9.1
Skin Type Compatibility
Ease of Application
Scent

Most important from
693 reviews

Skin Type Compatibility
Delivers fast relief from itching, calming sensitive skin and promoting visible healing.
Ease of Application
The spray bottle design makes application easy, even on hard-to-reach or sensitive areas.
Scent
Leaves skin looking healthier and reduces discomfort without an overpowering scent.

The HICC PET Itch Relief Spray is designed to quickly ease itching and skin irritation in dogs and cats. It contains hypochlorous acid (0.02%), a gentle but effective antimicrobial ingredient that helps heal wounds, hot spots, and other skin problems like insect bites and allergies. This makes it a strong option for pets dealing with redness, sores, or yeast infections.

The spray's formula is hypoallergenic, making it suitable for sensitive skin without causing extra irritation. Its continuous spray bottle with a fine mist facilitates easy application, even on tricky areas like paws or the face, which is helpful for pets that are hard to handle. The product also dries reasonably fast and doesn’t have a strong scent, so it won’t bother your pet or you while it works.

It is important to note that while this spray is great for soothing and protecting skin, it’s not a heavy-duty medication for severe infections and should be used as part of a broader care routine recommended by a vet. The 10 oz size is convenient for regular use but might run out quickly if you have multiple pets or frequent skin issues. This spray serves as a practical, vet-recommended choice for pet owners looking to manage everyday itching and minor skin troubles safely and easily.

Rating
9.1
Skin Type Compatibility
Ease of Application
Scent

Most important from
693 reviews

Skin Type Compatibility
Delivers fast relief from itching, calming sensitive skin and promoting visible healing.
Ease of Application
The spray bottle design makes application easy, even on hard-to-reach or sensitive areas.
Scent
Leaves skin looking healthier and reduces discomfort without an overpowering scent.
#3

Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray, 8oz – Easy to Use Spray for Dogs & Cats – Helps Alleviate Sensitive Skin, Scratching, and Licking of Coat (1 Pack)

Rating
8.8
Ease of Application
Scent

Most important from
41595 reviews

Ease of Application
Convenient application with no need for bathing, although drying the area can be a hassle.
Scent
The mild and citrusy scent is a pleasant bonus.

The Veterinary Formula Clinical Care Hot Spot & Itch Relief Medicated Spray is a well-rounded option for dogs and cats suffering from hot spots, itching, and skin irritation. One of its main strengths lies in its active ingredients, which include lidocaine, hydrocortisone, and allantoin. These ingredients work together to provide analgesic and anti-inflammatory benefits, helping to relieve discomfort and promote healing of damaged skin. Additionally, the inclusion of wheat germ oil helps moisturize the coat, making it suitable for pets with sensitive skin.

The spray is paraben, dye, and soap-free, which is a plus for pets with allergic reactions to these substances. It also has a citrus scent, which many users find pleasant. The spray is easy to apply due to its convenient nozzle, and it dries relatively quickly. However, some pets may find the spraying process a bit startling. The product is designed for pets over 12 weeks old and provides clear instructions on usage, which includes shaking well and applying twice daily for the first week, then reducing frequency as needed.

On the downside, while it is effective for many users, some may find it less effective on severe cases of hot spots or itching. Additionally, while the spray is designed to be non-irritating, individual pets may still experience irritation in rare cases. Priced affordably, it offers good value for money, and its vet-recommended status adds to its credibility. In conclusion, this spray is a solid choice for pet owners looking for an accessible and effective solution to hot spots and itch relief in their pets.

Rating
8.8
Ease of Application
Scent

Most important from
41595 reviews

Ease of Application
Convenient application with no need for bathing, although drying the area can be a hassle.
Scent
The mild and citrusy scent is a pleasant bonus.

Buying Guide for the Best Hot Spot Spray For Dogs

Choosing the right hot spot spray for your dog is crucial to ensure their comfort and health. Hot spots, also known as acute moist dermatitis, are painful and itchy areas on a dog's skin that can become infected if not treated properly. A good hot spot spray can provide relief, promote healing, and prevent further irritation. When selecting a hot spot spray, it's important to consider several key specifications to ensure you pick the best product for your dog's needs.
Active IngredientsActive ingredients are the components in the spray that provide therapeutic effects. They are important because they determine the effectiveness of the spray in treating hot spots. Common active ingredients include hydrocortisone for reducing inflammation, lidocaine for pain relief, and natural ingredients like aloe vera and tea tree oil for soothing and healing. If your dog has sensitive skin or allergies, opt for sprays with natural ingredients. For severe cases, a spray with hydrocortisone might be more effective.
Antimicrobial PropertiesAntimicrobial properties help prevent and treat infections caused by bacteria, fungi, or yeast. This is important because hot spots can easily become infected, leading to more serious health issues. Look for sprays that contain ingredients like chlorhexidine or benzalkonium chloride, which are effective antimicrobials. If your dog is prone to infections or if the hot spot appears to be infected, choosing a spray with strong antimicrobial properties is essential.
Ease of ApplicationEase of application refers to how simple and convenient it is to apply the spray to your dog's hot spot. This is important because a product that is difficult to apply can cause additional stress for both you and your dog. Sprays with a fine mist applicator are generally easier to use and ensure even coverage. If your dog is particularly fidgety or anxious, look for a spray that can be applied quickly and easily.
Drying TimeDrying time is the amount of time it takes for the spray to dry on your dog's skin. This is important because a fast-drying spray can prevent your dog from licking or scratching the treated area, which can further irritate the hot spot. Sprays that dry quickly are generally more convenient and effective in preventing additional discomfort. If your dog tends to lick or scratch the treated area, opt for a spray with a quick drying time.
ScentScent refers to the smell of the spray. This is important because a strong or unpleasant scent can be off-putting for both you and your dog. Some dogs may be sensitive to certain scents, which can cause additional stress or discomfort. Look for sprays with a mild or pleasant scent, or those labeled as unscented. If your dog is sensitive to smells or if you prefer a more neutral scent, choose a spray with a mild or no fragrance.
Skin Type CompatibilitySkin type compatibility refers to how well the spray works with your dog's specific skin type. This is important because dogs with sensitive or dry skin may react differently to certain ingredients. Some sprays are formulated specifically for sensitive skin, while others are designed for normal or oily skin. If your dog has sensitive or dry skin, look for a spray that is gentle and moisturizing. For dogs with normal or oily skin, a standard formulation should suffice.

FAQ

Most Popular Categories Right Now