10 Best Hydrocortisone Creams 2025 in the United States

Amazon Basic Care Maximum Strength Hydrocortisone 1 Percent Anti-Itch Cream is a great option for those in need of quick relief from various skin irritations. Its main active ingredient, hydrocortisone 1%, is well-regarded by doctors for effectively managing itchiness caused by conditions like eczema, psoriasis, and insect bites. The cream is further enriched with vitamins A, D, and E, along with aloe, which provide additional soothing and moisturizing benefits, making it ideal for those with dry or sensitive skin.

The inclusion of ten moisturizers helps in keeping the skin hydrated while alleviating irritation and redness. This product is suitable for frequent use, though it’s always best to follow the instructions on the packaging or your doctor's advice regarding duration and frequency. However, being a 1% hydrocortisone cream, it might not be sufficient for severe conditions or those needing stronger medication.

Also, as it is sold in a 2-ounce tube, it might run out quickly with regular use. Nonetheless, it's a practical addition to any first aid kit for tackling common skin problems efficiently.

The Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe is a practical option for those seeking quick relief from itchiness and inflammation caused by conditions like eczema, psoriasis, and poison ivy. The cream's primary strength lies in its active ingredient, 1% hydrocortisone, which is the maximum strength available without a prescription. This ensures potent itch relief that kicks in under 10 minutes and can last for hours, making it highly effective for fast and lasting comfort.

Additionally, the inclusion of soothing aloe and a fragrance-free, dye-free formula makes it gentle on sensitive skin, adding to its appeal for those with delicate or easily irritated skin types. The cream also benefits from being recognized as the #1 doctor-recommended over-the-counter anti-itch brand, adding a layer of trustworthiness and reliability to its profile.

On the downside, while the product is effective in providing temporary relief, it may not be suitable for long-term use without medical supervision due to the presence of hydrocortisone. Prolonged use might lead to skin thinning or other side effects associated with steroid creams. The inactive ingredients list includes parabens and mineral oil, which might be a concern for those with sensitivities to these compounds or those looking for a more natural formulation. This cream is best suited for individuals in need of a quick, potent solution to manage flare-ups of itchiness and inflammation but should be used cautiously and according to usage guidelines to avoid potential side effects.

Aquaphor Children's Itch Relief Ointment is a 1% hydrocortisone anti-itch ointment that comes in a pack of two 1-ounce tubes. It is suitable for children aged 2 and up, making it a good choice for families with young children. This product offers up to 12 hours of relief from itching caused by eczema, skin irritation, rashes, and psoriasis. Additionally, it provides relief from outdoor irritations such as insect bites and poison ivy.

The formulation is fragrance-free, paraben-free, and hypoallergenic, catering to sensitive skin types. However, as with all hydrocortisone products, it is recommended to use it for short-term relief and follow usage instructions carefully to avoid potential side effects from prolonged use. The compact size of the tubes makes them convenient for travel or keeping in a first aid kit.

While the product effectively delivers on its promise of itch relief, users should be aware that it is not a long-term solution and is best used as a temporary measure to alleviate discomfort.