10 Best Laxatives For Severe Constipation 2025 in the United States

MiraLAX Gentle Constipation Relief is an osmotic laxative powder designed for individuals facing severe constipation. One of its main strengths is how it works naturally with the water in your body to hydrate and soften stools, making bowel movements easier without the harsh side effects often associated with stimulant laxatives. Users can expect results within 1 to 3 days, which is a reasonable timeframe for relief.

Physician recommendations back MiraLAX, having been the #1 OTC laxative brand since its launch in 2007. This level of trust may give users confidence in its effectiveness. Additionally, the product is free from gluten, sugar, and preservatives, making it a suitable choice for those with dietary restrictions.

On the downside, while the gentle action of MiraLAX is a plus, it may not provide immediate relief for individuals who need quicker results, as other types of laxatives may work faster. The powder must be dissolved in a beverage, which could be inconvenient for some users who prefer more straightforward forms of laxatives.

Amazon Basic Care ClearLax is an osmotic laxative containing Polyethylene Glycol 3350, the same active ingredient found in popular brands like MiraLAX. It works by drawing water into the bowel to soften stool and increase bowel movements, usually producing relief within 1 to 3 days. This makes it suitable for those dealing with occasional or severe constipation who need a gentle but effective option. The orange-flavored powder is easy to mix into any beverage, and it’s free from sugar, gluten, dyes, and grittiness, which can make it more pleasant to take. It’s designed for adults and kids 17 and older.

Since it is an osmotic laxative, it can be used safely for short-term relief; however, usage beyond a week should be under medical advice, especially for people with kidney problems or electrolyte imbalances. Side effects are generally mild but can include bloating or cramping. Polyethylene Glycol 3350 is widely recommended by doctors, which supports its reliability.

The onset of this product is slower compared to stimulant laxatives, so it may not be ideal if immediate relief is needed. It requires dissolving in liquid, which might be less convenient than tablets for some users. This product suits those seeking a doctor-trusted, gentle laxative option for managing severe constipation without harsh side effects.

MiraFAST Soft Chews are a saline laxative designed to relieve constipation relatively quickly, usually within 30 minutes to 6 hours. They contain magnesium hydroxide, which works by drawing water into the intestines to soften stools, making it easier to pass without causing the cramps some stimulant laxatives might bring. These soft chews come in kid-friendly blueberry and raspberry flavors and are suitable for ages 4 and up, which makes them convenient for family use. Because they are stimulant-free, they tend to be gentler on the digestive system.

The product is easy to carry around, fitting well into a busy lifestyle or travel plans. However, saline laxatives like MiraFAST are generally meant for short-term use and might not be suitable for people with certain health conditions like kidney problems or severe dehydration, so it's important to check with a doctor before use if you have underlying health concerns. While effective and fast-acting, frequent or long-term use isn't recommended as it can lead to electrolyte imbalances.

MiraFAST Soft Chews provide a reliable, quick, and gentle option for those needing fast relief from occasional severe constipation without the harsher side effects of stimulant laxatives.