10 Best Laxatives For Severe Constipation 2026 in the United States

MiraLAX Gentle Constipation Relief is an osmotic laxative powder designed for individuals facing severe constipation. One of its main strengths is how it works naturally with the water in your body to hydrate and soften stools, making bowel movements easier without the harsh side effects often associated with stimulant laxatives. Users can expect results within 1 to 3 days, which is a reasonable timeframe for relief.

Physician recommendations back MiraLAX, having been the #1 OTC laxative brand since its launch in 2007. This level of trust may give users confidence in its effectiveness. Additionally, the product is free from gluten, sugar, and preservatives, making it a suitable choice for those with dietary restrictions.

On the downside, while the gentle action of MiraLAX is a plus, it may not provide immediate relief for individuals who need quicker results, as other types of laxatives may work faster. The powder must be dissolved in a beverage, which could be inconvenient for some users who prefer more straightforward forms of laxatives.

MiraFAST Soft Chews are a saline laxative designed to relieve constipation relatively quickly, usually within 30 minutes to 6 hours. They contain magnesium hydroxide, which works by drawing water into the intestines to soften stools, making it easier to pass without causing the cramps some stimulant laxatives might bring. These soft chews come in kid-friendly blueberry and raspberry flavors and are suitable for ages 4 and up, which makes them convenient for family use. Because they are stimulant-free, they tend to be gentler on the digestive system.

The product is easy to carry around, fitting well into a busy lifestyle or travel plans. However, saline laxatives like MiraFAST are generally meant for short-term use and might not be suitable for people with certain health conditions like kidney problems or severe dehydration, so it's important to check with a doctor before use if you have underlying health concerns. While effective and fast-acting, frequent or long-term use isn't recommended as it can lead to electrolyte imbalances.

MiraFAST Soft Chews provide a reliable, quick, and gentle option for those needing fast relief from occasional severe constipation without the harsher side effects of stimulant laxatives.

GenCare Maximum Strength Senna Laxative offers a powerful dose of 25mg sennosides, a natural stimulant derived from senna leaves, designed for overnight relief from occasional severe constipation. Its natural approach gently encourages bowel movements by activating the intestines, usually within 6 to 12 hours, making it convenient to take before bedtime. This laxative can be effective for adults and children over 6, and it also helps ease gas and bloating linked with constipation.

Compared to brand-name options like Ex-Lax, it provides similar active ingredients at a more affordable price with a generous count of 100 tablets per bottle. However, as a stimulant laxative, it should not be used for extended periods without medical advice because prolonged use can lead to dependence or worsen bowel function. Some people might experience mild cramping or discomfort despite its claim of gentle action.

Those with certain health conditions, such as intestinal blockages, inflammatory bowel disease, or those who are pregnant, should consult a healthcare professional before use. This product is suitable for individuals seeking quick, natural relief from severe constipation episodes but is not ideal for long-term daily use or those with underlying health risks without doctor guidance.