10 Best Mattress Protectors 2025 in the United States

The SafeRest CloudGuard Twin XL Mattress Protector stands out due to its plush and fluffy padding, designed to offer a cloud-like comfort. Made from viscose fabric, it provides a luxurious feel, making it a comfortable choice for those seeking extra cushioning. Its 100% waterproof feature ensures that your mattress remains protected from spills, urine, perspiration, and other fluids, which is particularly beneficial for families with children or pets.

The protector is also machine washable, making it easy to clean and maintain. Simply wash on cold and tumble dry to refresh it, which adds to its convenience for busy households or Airbnb hosts. With its noiseless design, it allows for a peaceful sleep without the rustling sounds common with some mattress covers. The Twin XL size fits snugly, thanks to its pull-on closure type, ensuring it stays in place throughout the night.

However, while the extra padding offers great comfort, it may not be the best choice for those who prefer a firmer sleeping surface. Additionally, it does not specifically mention hypoallergenic properties, which might be a consideration for those with allergies. Despite these minor drawbacks, the SafeRest CloudGuard excels in comfort, protection, and ease of use, making it a strong contender for anyone looking to enhance their mattress's longevity and comfort.

The BEDLORE Waterproof Mattress Protector is designed to keep your mattress clean and dry, making it a solid choice for anyone looking to protect against spills, sweat, and stains. Its top layer features a soft brushed microfiber with a unique diamond quilted pattern, which adds comfort and prevents the filling from bunching up. The waterproofing uses an upgraded TPU film that effectively blocks liquids, which is especially beneficial for households with kids, pets, or seniors. The material is breathable enough to reduce heat build-up, helping you stay comfortable through the night without the noisy crinkling some waterproof protectors have.

It fits mattresses with a depth from 6 to 18 inches thanks to a strong elastic skirt that holds the cover securely in place, so it won’t slip off easily even if you move around a lot. Cleaning is straightforward since the protector is machine washable and dries quickly on low heat, though it shouldn’t be ironed or bleached. This protector balances comfort, durability, and practical protection well, making it a practical option for most home and hotel settings.

The SafeRest Sleepure Waterproof Mattress Protector is made from a blend of bamboo-derived viscose and polyester, which creates a soft, cool, and breathable surface ideal for a comfortable night's sleep. Its material feels smooth and gentle on the skin, making it a great choice for those who prefer a cooler sleeping environment. This protector is fully waterproof, effectively shielding your mattress from spills, sweat, and accidents without changing the mattress’s softness, which means you won’t feel a plastic or crinkly layer beneath your sheets.

It’s fitted with stretchable pockets that securely fit mattresses up to 18 inches deep, so it stays in place quietly without slipping or bunching—important for uninterrupted rest. One of the big pluses is its quiet operation; unlike some protectors that make noise when you move, this one is designed for stillness, helping maintain a peaceful sleep environment. The protector is also hypoallergenic, as it is OEKO-TEX Standard 100 certified, ensuring it is free from harmful chemicals and suitable for people with sensitivities. Cleaning is simple since it’s machine washable and has a pull-on style without zippers or extra padding, making maintenance hassle-free. Available in many sizes, including queen, it’s versatile enough to fit different beds.

On the downside, it doesn’t have added padding, so if you’re looking for extra cushioning or a mattress topper feel, this won’t provide that. Also, while it is waterproof, like most fabric protectors, it may require prompt cleaning if a large spill occurs to avoid moisture buildup. This mattress protector provides a good balance of protection, comfort, and ease of care, making it a solid choice for anyone wanting to keep their mattress clean and dry without sacrificing sleep quality.