10 Best Mosquito Bite Treatments 2026 in the United States

The After Bite Advanced Formula offers effective itch relief for mosquito bites and other insect bites such as fire ants and bees. This treatment uses Sodium Bicarbonate (5%) as the active ingredient, which is known for its soothing properties for minor skin irritations. The product comes in a convenient, portable pen applicator, making it easy to carry around and ideal for on-the-go use. This is particularly useful for outdoor enthusiasts and families who may encounter bug bites frequently.

The formula is paraben-free and cruelty-free, which may appeal to those with sensitive skin and those who prefer products made without harsh chemicals. It is recognized as a pharmacist-recommended brand, supporting its credibility in providing fast-acting relief. The product's additional benefits include being able to treat minor skin irritations beyond insect bites, such as poison ivy, making it versatile for various first aid needs.

Its small size (0.5 oz per pen) might not last long for frequent use, but the pack includes four pens, which helps mitigate this issue to some extent. This treatment is best suited for those looking for a reliable, portable solution to manage insect bites and other minor skin irritations, particularly when traveling or spending time outdoors.

Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe is a dependable option for mosquito bite treatments. It features 1% hydrocortisone, which is the highest strength available without a prescription, making it effective for quick relief from itching and inflammation. One of its main strengths is its fast-acting nature; it starts to relieve itch in under 10 minutes and provides relief that lasts for hours.

This is particularly beneficial for mosquito bites as well as other skin irritations like eczema and poison ivy. The inclusion of aloe vera adds a soothing element to the cream, which can be particularly comforting for sensitive skin. The product is also fragrance-free and dye-free, reducing the likelihood of skin irritation. However, it does contain several inactive ingredients such as parabens and mineral oil, which might not be suitable for everyone, especially those with very sensitive skin or allergies to these substances.

The cream is also relatively lightweight and easy to carry, making it convenient for on-the-go relief. While it is highly recommended by doctors and has a solid reputation, it may not be the best choice for someone looking for an all-natural or organic solution. This product is ideal for those in need of fast and effective itch relief, but users with specific sensitivities should review the ingredient list carefully.

The Beurer BR90 is a small, portable electronic device designed to relieve itching and swelling from mosquito bites and other insect stings using heat instead of chemicals. Since it uses natural heat rather than creams or sprays, it’s a good choice for people who want a chemical-free, non-toxic option — even safe for pregnant users. The device heats up quickly and offers two treatment durations (3 or 6 seconds) so you can choose a gentler option for sensitive skin.

Its built-in light makes it handy to use at night or in low-light situations, perfect for outdoor activities like camping or barbecues. Being battery-powered and compact, it’s easy to carry around. However, because it relies on heat, it must be applied soon after the bite to work effectively and might not replace traditional creams for severe reactions. Also, some users may find the need for batteries inconvenient compared to always-ready topical treatments.

The BR90 is well suited for those who prefer a natural, fuss-free approach to quickly soothe mosquito bites and minor insect stings without applying anything on the skin.