10 Best Puppy Wormers 2025 in the United States

PetArmor Sure Shot 2X is a liquid de-wormer designed to treat and prevent common roundworms and hookworms in dogs, including puppies as young as 2 weeks old. Its liquid form makes dosing flexible and easy to adjust based on your puppy's weight, with a recommended dosage of 1 teaspoon per 10 pounds of body weight. The product targets four types of worms and also helps prevent reinfestation of large roundworms in adult dogs, which is beneficial for dogs living in worm-prone environments.

The recommended treatment schedule involves multiple doses for puppies between 2 and 10 weeks old, while adult dogs in high-risk environments can be treated monthly. This dosing schedule requires careful attention from the owner. The product is vet-quality, widely recommended, and has a strong customer rating indicating good effectiveness and safety.

PetArmor Sure Shot 2X serves as a practical and safe choice for early and ongoing worm control in puppies and dogs, especially for owners who prefer liquid medication and seek a product with proven results. However, while it covers key worm types, it may not treat all possible worms, so consulting a vet for a comprehensive worm control plan is advisable.

The Safe-Guard (Fenbendazole) Dewormer Liquid is a versatile oral solution that effectively treats various types of worms including stomach worms, lungworms, hookworms, and nodular worms. This broad spectrum makes it a reliable choice for addressing multiple parasitic issues in puppies.

It is administered orally, which can be convenient for most pet owners, though some pets may resist liquid medications compared to chewable options. One of its notable strengths is that it is generally safe, but it’s crucial to follow a veterinarian's advice for proper dosage based on the puppy’s age and weight. The product’s safety warnings are more pertinent to livestock but underline the importance of consulting with a vet before use.

The frequency of treatment isn’t specified here, so it’s best to refer to veterinary guidance for an appropriate schedule. While this product is highly effective for various types of worms, the lack of specific usage instructions for puppies may require more direct consultation with a vet to ensure it’s used safely and effectively. Monitoring your puppy after administration and reporting any adverse effects to your vet is essential.

The Sentry PET Care HC Worm X Plus 7 Way De-Wormer is designed for puppies and small dogs weighing between 6 and 25 pounds, starting from 12 weeks old. It treats a broad range of worms including two types of tapeworms, two types of roundworms, and three types of hookworms, covering most common worm infections in dogs. The product comes as chewable tablets with a liver flavor, making it easier to give to your puppy without needing to hide medicine in food. You simply give one tablet for puppies up to 12 pounds and two tablets for those between 12 and 25 pounds. It contains active ingredients pyrantel pamoate and praziquantel, which are common in veterinary wormers, yet it’s available over-the-counter without a prescription, making it convenient for pet owners.

Regular treatment is advised to keep worms under control, and subscribing to a regular delivery can help maintain this routine. On the safety side, it is generally safe for puppies 12 weeks and older when used as directed, though as with any medication, watching for side effects and consulting your vet if unsure is a good idea. It is trusted by many and aligns well with veterinary recommendations for small breed puppies needing broad-spectrum worm treatment. It is not suitable for puppies under 12 weeks or dogs over 25 pounds, so a different product would be needed if your pet falls outside this range. This wormer offers an easy-to-administer, effective option for small puppies needing protection against a wide variety of worms, balancing convenience and veterinary-grade ingredients.