10 Best Shampoo For Itching Dogs 2026 in the United States

Pawfume Dog Shampoo and Conditioner is designed to cater to dogs with sensitive skin, particularly those prone to itching. It is hypoallergenic and contains a probiotic formula aimed at keeping your dog's coat fresh and shiny. The shampoo boasts a calming lavender scent, which can be soothing for dogs and their owners.

Additionally, it features moisturizing and detangling properties, making it a good choice for dogs with dry or tangled fur. The product is eco-friendly and alcohol-free, aligning with health-conscious pet care preferences. The 2-pack, with a substantial 24 fluid ounces total, offers good value for long-term use.

This product is suitable for all life stages and is well-suited to pet owners looking for a quality, fragrant, and moisturizing dog shampoo that addresses general skin and coat health rather than specialized medical needs.

Pet Honesty Chlorhexidine Cat & Dog Seasonal Itch Relief Shampoo is a specialized product designed to address various skin issues in dogs and cats. One of its strengths is the inclusion of Chlorhexidine and Ketoconazole, which are known for their effectiveness in treating skin issues, including itchiness, hot spots, and dandruff. The addition of aloe vera provides moisturizing properties, making it gentle on irritated and sensitive skin.

This shampoo also has a light cucumber melon scent, which helps in deodorizing and combating bad odors associated with skin problems. The 16 oz bottle with a pump dispenser makes it easy to use and apply during bathing sessions. It is made in the USA in a GMP certified facility, which ensures high safety and quality standards. However, some pet owners might find the scent or specific ingredients not suitable for their pets, especially if they have allergies.

While the product is non-medicated, its combination of ingredients serves both cleansing and therapeutic purposes. The formulation has received highly positive customer reviews, indicating its effectiveness and satisfaction among users. This shampoo is most beneficial for pet owners looking for a reliable product to manage their pets' itchy and irritated skin while also maintaining a clean and healthy coat.

Douxo S3 Pyo Shampoo is a medicated shampoo designed to help dogs (and cats) with bacterial or yeast skin infections that often cause itching and irritation. It contains 3% chlorhexidine, a strong antiseptic to fight infection, and 0.5% ophytrium, a natural ingredient known for soothing skin and supporting its protective barrier. This combination helps reduce yeast and bacteria while moisturizing the skin to prevent dryness, which is important for dogs with sensitive or irritated skin.

The shampoo has a gentle pH balance and avoids harsh ingredients like soaps, sulfates, parabens, and dyes, making it suitable even for pets with allergies. Its scent is a mild mix of coconut and vanilla, which many owners find pleasant without being overpowering. The liquid formulation is easy to apply and recommended for all life stages. The shampoo is well-regarded by veterinarians and users alike, with many reporting noticeable improvements within a week.

A minor drawback is that it requires a 10-minute leave-on time to be effective, which might test the patience of some pets during bath time. Also, since it’s medicated, using it as directed by a vet is important to avoid overuse. This makes Douxo S3 Pyo Shampoo a reliable choice for pet owners looking to manage itchy skin caused by infections while also caring for their dog's overall skin health.