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10 Best Sleeping Pill For Dogs 2025 in the United States

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Our Top Picks

#1

Winner

Natural Hemp Calming Chews for Dogs Maximum Strength - Hemp & Melatonin Dog Anxiety Relief - Calming Aid Supplement with Valerian Root - Stress, Separation & Thunder Support - (Duck 90 Ct)

Rating
9.8
Chosen by1,416
Duration of Effect

Most important from
22114 reviews

Duration of Effect
The calming effect is noticeable, making pets less jittery and more relaxed during stressful situations like vet visits or fireworks.

Pet Honesty Natural Hemp Calming Chews for Dogs are designed to help manage your dog's anxiety and stress without sedating them. These chews are formulated with natural ingredients like hemp, melatonin, chamomile, valerian root, and ginger, which are known for their calming properties. This makes them a gentle yet effective solution for dogs who experience anxiety due to thunderstorms, separation, car rides, and vet visits.

The addition of melatonin can be particularly beneficial for inducing a sense of calmness without causing drowsiness, and the supplement takes effect within 30-45 minutes, providing relatively quick relief. The chews are made in the USA with high-quality ingredients and do not contain added sugar, wheat, corn, GMOs, or harsh preservatives, making them a safe choice for your pet. Additionally, they come in a tasty duck flavor that most dogs enjoy, eliminating the need to hide pills in their food.

While the product is vet-reviewed and recommended, it's always wise to consult with your own veterinarian before starting any new supplement, especially if your dog has underlying health conditions. Some dogs might not respond equally to natural remedies, and there could be mild side effects such as gastrointestinal upset for sensitive dogs. The 90-count package provides a good supply but be mindful of the dosage instructions to avoid over-sedation. If your dog is under 25 lbs, one chew is recommended; for dogs between 26-75 lbs, two chews; and for dogs over 75 lbs, three chews. This product offers a natural and non-sedative option to help keep your dog calm during stressful situations, though individual results may vary.

Rating
9.8
Chosen by1,416
Duration of Effect

Most important from
22114 reviews

Duration of Effect
The calming effect is noticeable, making pets less jittery and more relaxed during stressful situations like vet visits or fireworks.
#2

Zesty Paws Calming Chews for Dogs Composure & Relaxation for Everyday Stress & Separation Peanut Butter 90 Count

Rating
9.6
Form
Duration of Effect

Most important from
27373 reviews

Form
Dogs seem to love the peanut butter flavor, making it easy to administer these chews.
Duration of Effect
The treats work quickly, calming anxious dogs within thirty minutes, allowing them to relax and enjoy their surroundings.

Zesty Paws Calming Chews are designed to help dogs manage everyday stress and anxiety. These chews come in a peanut butter flavor that most dogs will find appealing. The key active ingredient is Suntheanine, a high-grade form of L-Theanine, which is known for its calming effects. Additionally, the chews contain Ashwagandha, Valerian Root, Organic Hemp Seed Powder, and other natural ingredients that support relaxation.

The dosage varies based on the size of the dog, making it easy to adjust to your pet's needs - small dogs need one chew, medium dogs require two, and large dogs need three chews daily. These chews are suitable for all life stages and breeds. The product is chunk-shaped, making it easy for your dog to consume.

The duration of effect can vary but generally should help keep your dog calm during stressful situations like storms, car rides, or fireworks. With over 24,000 reviews and a 4.0-star rating, many customers have found these chews helpful for their pets.

Rating
9.6
Form
Duration of Effect

Most important from
27373 reviews

Form
Dogs seem to love the peanut butter flavor, making it easy to administer these chews.
Duration of Effect
The treats work quickly, calming anxious dogs within thirty minutes, allowing them to relax and enjoy their surroundings.
#3

Native Pet Calming Chews for Dogs - Melatonin for Dogs Anxiety Relief - Grain Free All Natural Hemp Calming Treats & L-Theanine Helps Manage Stress & Separation Anxiety - Puppy Sleep Aid - 30 Chews

Rating
9.4
Active Ingredient
Dosage
Form

Most important from
3343 reviews

Active Ingredient
Formulated with all-natural ingredients, they are gentle and safe even for puppies.
Dosage
Increasing the dosage beyond the recommendation can produce a stronger calming effect for smaller dogs.
Form
The tasty chicken flavor makes them feel like treats rather than medication, encouraging easy administration.
Duration of Effect
These chews effectively calm dogs and help them sleep soundly without sedation.

Native Pet Calming Chews for Dogs use melatonin as the main active ingredient to help calm your dog and support better sleep without causing sedation. These treats also include hemp seed and L-Theanine, which work together to reduce stress and anxiety, especially useful during travel, loud noises, or separation. The chews come in an easy-to-give, air-dried form that dogs find tasty thanks to real chicken flavor, making them feel like treats rather than medication.

The dosage guide is straightforward: one chew per 25 pounds of dog weight, which makes it simple to administer the right amount. Formulated with all-natural ingredients and free from grains or fillers, these chews are a good option for dogs with dietary sensitivities. They are vet-formulated and safe for puppies, which adds reassurance about their suitability and safety.

Made in the USA, these calming chews provide a gentle, natural way to ease anxiety and help pets relax and sleep better.

Rating
9.4
Active Ingredient
Dosage
Form

Most important from
3343 reviews

Active Ingredient
Formulated with all-natural ingredients, they are gentle and safe even for puppies.
Dosage
Increasing the dosage beyond the recommendation can produce a stronger calming effect for smaller dogs.
Form
The tasty chicken flavor makes them feel like treats rather than medication, encouraging easy administration.
Duration of Effect
These chews effectively calm dogs and help them sleep soundly without sedation.

Buying Guide for the Best Sleeping Pill For Dogs

Choosing the right sleeping pill for your dog is crucial to ensure their safety and well-being. It's important to understand that not all sleeping pills are created equal, and what works for one dog may not work for another. Always consult with your veterinarian before giving your dog any medication. Here are some key specifications to consider when selecting a sleeping pill for your dog.
Active IngredientThe active ingredient is the main component that induces sleep. It's important because different active ingredients can have different effects on your dog. Some common active ingredients include diphenhydramine, melatonin, and valerian root. Diphenhydramine is often used for its sedative properties but can cause drowsiness. Melatonin is a natural hormone that regulates sleep and is generally considered safe for dogs. Valerian root is a herbal remedy that can help with anxiety and sleep. Choose an active ingredient based on your dog's specific needs and any recommendations from your vet.
DosageDosage refers to the amount of medication your dog needs to take. This is important because giving too much or too little can be ineffective or harmful. Dosage is usually determined by your dog's weight and age. For example, smaller dogs will require a lower dosage compared to larger dogs. Always follow the dosage instructions provided by your vet or on the medication packaging. If you're unsure, consult your vet to determine the correct dosage for your dog.
FormThe form of the sleeping pill can vary, including tablets, capsules, liquid, or chewable treats. This is important because some dogs may have preferences or difficulties with certain forms. Tablets and capsules can be hidden in food, but some dogs may spit them out. Liquid forms can be easier to administer but may require a syringe. Chewable treats are often more palatable and easier to give to your dog. Choose a form that you think will be easiest for you to administer and that your dog will accept.
Side EffectsSide effects are the unwanted reactions your dog might have to the medication. This is important because some side effects can be serious and affect your dog's health. Common side effects of sleeping pills can include drowsiness, dry mouth, and gastrointestinal issues. More severe side effects can include allergic reactions or changes in behavior. Always monitor your dog after giving them a new medication and consult your vet if you notice any adverse reactions. Choose a sleeping pill with minimal side effects and always follow your vet's guidance.
Duration of EffectThe duration of effect refers to how long the medication will help your dog sleep. This is important because you want to ensure that the medication lasts long enough to help your dog get a full night's rest. Some sleeping pills may only last a few hours, while others can last throughout the night. Consider your dog's sleep patterns and needs when choosing a medication. If your dog has trouble staying asleep, a longer-lasting medication may be more suitable.
Veterinary ApprovalVeterinary approval means that the medication has been recommended or prescribed by a veterinarian. This is crucial because a vet can provide professional advice tailored to your dog's specific health needs. Not all over-the-counter sleeping pills are safe for dogs, and some may interact with other medications your dog is taking. Always consult your vet before giving your dog any sleeping pill to ensure it is safe and appropriate for their condition.

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