10 Best Spider Killers 2025 in the United States

The Ortho BugClear Insect Killer for Lawns & Landscapes Concentrate is a versatile insecticide that targets 235 types of bugs, including spiders, ants, ticks, mosquitoes, and fleas. This product stands out for its quick action, as it begins to kill insects within minutes and offers long-lasting control. This makes it highly effective for those who need immediate and durable pest management for their outdoor areas, including lawns, home perimeters, trees, and shrubs.

The concentrate form of the product requires mixing and must be applied with a separate sprayer like the Ortho Dial N' Spray or a tank sprayer, making it slightly less convenient for those looking for a ready-to-use solution. However, its flexibility in application methods can be seen as a benefit for those who already own spraying equipment.

Safety and environmental impact are important considerations, and while the product is effective, it does not specify being organic or eco-friendly, which may be a drawback for environmentally-conscious users. Additionally, it’s unscented and relatively lightweight, making it easy to handle during application. The product is best suited for those who need comprehensive, long-term bug control in medium to large outdoor areas and are comfortable with the mixing and application process.

Miss Muffet's Revenge by Wet & Forget is a spider killer designed for both indoor and outdoor use. It features Bifenthrin as the active ingredient, which is effective against most spiders except Black Widow and Brown Recluse. One of its strongest points is its long-lasting residual effect, providing protection for up to 12 months with a single application. The attached sprayer is convenient, allowing you to spray up to 10 feet, which is great for those hard-to-reach areas.

Users have found it easy to apply, with the recommendation to use it in calm weather and allow it to dry completely for the best results. However, safety precautions should be taken to avoid entering treated areas before the spray is dry. The product has an unlimited shelf life and is ready to use straight out of the package, which adds to its convenience. On the downside, it is not suitable for eliminating Black Widow and Brown Recluse spiders, which could be a significant limitation for some users. Additionally, while it is effective, Bifenthrin is a chemical insecticide, which may raise environmental concerns for those looking for eco-friendly options.

If you need a reliable solution for most spider issues and ease of use is a priority, this product is a strong candidate.

The Hot Shot Ant, Roach & Spider Killer is a versatile insecticide spray designed for use both indoors and outdoors. It comes in a twin pack, which means you get two 17.5-ounce aerosol cans. One of its main strengths is its fast-acting formula that kills listed insects on contact, making it effective for immediate relief. However, it's important to note that while it effectively kills a variety of insects, its residual effect lasts up to 3 months only on non-porous surfaces and does not cover spiders, fleas, and certain types of ants such as carpenter, pharaoh, and fire ants. This could be a limitation if you're specifically targeting those pests.

The active ingredients, Imiprothrin and Lambda-Cyhalothrin, are commonly used in insecticides and are effective for rapid knockdown of insects. The spray is fairly easy to use, just point and spray, making it convenient for quick applications both inside your home and in your yard. Safety is always a concern with insecticides, and while the spray is effective, it should be used with caution around pets and children due to its chemical content.

As for environmental impact, like most chemical sprays, it’s not the most eco-friendly option and should be used sparingly to minimize any potential harm to beneficial insects and the surrounding environment. This product would be particularly beneficial for someone looking for an all-around insect killer for both indoor and outdoor use, but if your primary concern is spiders, you might want to consider options specifically targeted towards them.