10 Best Spider Killers 2025 in the United States

The Ortho BugClear Insect Killer for Lawns & Landscapes Concentrate is a versatile insecticide that targets 235 types of bugs, including spiders, ants, ticks, mosquitoes, and fleas. This product stands out for its quick action, as it begins to kill insects within minutes and offers long-lasting control. This makes it highly effective for those who need immediate and durable pest management for their outdoor areas, including lawns, home perimeters, trees, and shrubs.

The concentrate form of the product requires mixing and must be applied with a separate sprayer like the Ortho Dial N' Spray or a tank sprayer, making it slightly less convenient for those looking for a ready-to-use solution. However, its flexibility in application methods can be seen as a benefit for those who already own spraying equipment.

Safety and environmental impact are important considerations, and while the product is effective, it does not specify being organic or eco-friendly, which may be a drawback for environmentally-conscious users. Additionally, it’s unscented and relatively lightweight, making it easy to handle during application. The product is best suited for those who need comprehensive, long-term bug control in medium to large outdoor areas and are comfortable with the mixing and application process.

The Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 is a versatile choice for managing not just spiders but also a range of other insects like ants, roaches, and fleas. This makes it a handy all-in-one solution for households dealing with multiple types of pests. One of its major strengths is its longevity, providing up to 12 months of protection indoors on non-porous surfaces, which means less frequent reapplication is needed.

This product is easy to use, particularly if you have the Comfort Wand from the original container, allowing for precise application in both indoor and outdoor settings like kitchens, bathrooms, and around the house perimeter. It is unscented, which is a plus for those sensitive to strong chemical smells. However, the product's safety profile is crucial to consider, especially around pets and children. While it is effective, it's important to follow the usage instructions carefully to avoid any potential harm.

The environmental impact is another aspect to note; chemical insecticides can have broader ecological effects, so this product might not be the best choice for those seeking an eco-friendly option. The 1-gallon size can be cumbersome to handle, and although it covers a good area, those with extensive pest problems might find it insufficient for larger properties. This insect killer is highly effective and user-friendly for those needing comprehensive pest control, but safety and environmental concerns should be weighed before use.

Miss Muffet's Revenge by Wet & Forget is a spider killer designed for both indoor and outdoor use. It features Bifenthrin as the active ingredient, which is effective against most spiders except Black Widow and Brown Recluse. One of its strongest points is its long-lasting residual effect, providing protection for up to 12 months with a single application. The attached sprayer is convenient, allowing you to spray up to 10 feet, which is great for those hard-to-reach areas.

Users have found it easy to apply, with the recommendation to use it in calm weather and allow it to dry completely for the best results. However, safety precautions should be taken to avoid entering treated areas before the spray is dry. The product has an unlimited shelf life and is ready to use straight out of the package, which adds to its convenience. On the downside, it is not suitable for eliminating Black Widow and Brown Recluse spiders, which could be a significant limitation for some users. Additionally, while it is effective, Bifenthrin is a chemical insecticide, which may raise environmental concerns for those looking for eco-friendly options.

If you need a reliable solution for most spider issues and ease of use is a priority, this product is a strong candidate.