10 Best Spider Repellents 2026 in the United States

The Ortho Home Defense Insect Killer is a spray designed to control a variety of common household pests, including spiders, ants, cockroaches, and more. Its active ingredients, bifenthrin and zeta-cypermethrin, are known for effectively killing and repelling insects. This product offers a long-lasting barrier—up to 12 months—when applied on indoor non-porous surfaces and outdoor perimeters like foundations and patios. This makes it a good choice if you want extended protection without frequent reapplication.

The spray comes in a large 1.1-gallon size (two containers included) and features battery-powered comfort wands for easier application, which helps reach tricky corners and reduces mess. It's suitable for use both inside your home (kitchens, bathrooms) and outside around entry points where spiders and other insects might enter. Since it's a chemical spray, it’s important to follow safety instructions carefully, especially around children and pets. Some users might find the weight and size a bit bulky, but the comfort wand helps with handling.

If you want a spider repellent that also covers a wide range of insects and offers long-lasting results, this product fits well. It is effective but not a natural or chemical-free option, which could be a downside if you prefer eco-friendly products.

Mighty Mint Gallon is a natural spider repellent that uses concentrated peppermint oil to keep spiders and other pests away. Its main strength lies in being pet- and family-safe, making it ideal for households with children and pets since it avoids harsh chemicals and fumes. The peppermint oil acts as the active ingredient, providing a fresh minty scent that lingers gently without overwhelming. This product covers a large area effectively thanks to its generous 128 oz size, which is convenient for both indoor and outdoor use, including kitchens, patios, and entryways.

It is easy to apply as a spray and does not stain surfaces, which adds to its user-friendliness. However, since it is an oil-based natural repellent, its effectiveness might not last as long as chemical alternatives, requiring more frequent applications to maintain protection. This product is well suited for those looking for a gentle, eco-friendly pest control option rather than a heavy-duty solution.

Mighty Mint Peppermint Oil Insect Repellent Spray is a natural, plant-based option that effectively keeps spiders and other bugs like ants and roaches away. Its main active ingredient is extra-concentrated peppermint oil, which acts as a natural deterrent without using harsh chemicals. This makes it a safe choice for homes with kids and pets, especially since it doesn't produce strong fumes or leave stains.

The spray can be used both indoors and outdoors on areas like baseboards, entryways, and patios, making it versatile for many spots where pests might appear. It comes ready to use in a convenient 16-ounce bottle, allowing you to target problem areas quickly and easily. Additionally, it leaves behind a fresh mint scent that’s pleasant but not overpowering, which is great for those sensitive to strong smells.

This product is suitable for general spider and insect control, but for heavy infestations, stronger treatments might be necessary. It is a good choice for those seeking a gentle, natural spider repellent that’s safe around family and pets and easy to use in various home environments.