10 Best Spider Repellents 2025 in the United States

The Ortho Home Defense Insect Killer is a spray designed to control a variety of common household pests, including spiders, ants, cockroaches, and more. Its active ingredients, bifenthrin and zeta-cypermethrin, are known for effectively killing and repelling insects. This product offers a long-lasting barrier—up to 12 months—when applied on indoor non-porous surfaces and outdoor perimeters like foundations and patios. This makes it a good choice if you want extended protection without frequent reapplication.

The spray comes in a large 1.1-gallon size (two containers included) and features battery-powered comfort wands for easier application, which helps reach tricky corners and reduces mess. It's suitable for use both inside your home (kitchens, bathrooms) and outside around entry points where spiders and other insects might enter. Since it's a chemical spray, it’s important to follow safety instructions carefully, especially around children and pets. Some users might find the weight and size a bit bulky, but the comfort wand helps with handling.

If you want a spider repellent that also covers a wide range of insects and offers long-lasting results, this product fits well. It is effective but not a natural or chemical-free option, which could be a downside if you prefer eco-friendly products.

Mighty Mint Gallon is a natural spider repellent that uses concentrated peppermint oil to keep spiders and other pests away. Its main strength lies in being pet- and family-safe, making it ideal for households with children and pets since it avoids harsh chemicals and fumes. The peppermint oil acts as the active ingredient, providing a fresh minty scent that lingers gently without overwhelming. This product covers a large area effectively thanks to its generous 128 oz size, which is convenient for both indoor and outdoor use, including kitchens, patios, and entryways.

It is easy to apply as a spray and does not stain surfaces, which adds to its user-friendliness. However, since it is an oil-based natural repellent, its effectiveness might not last as long as chemical alternatives, requiring more frequent applications to maintain protection. This product is well suited for those looking for a gentle, eco-friendly pest control option rather than a heavy-duty solution.

The Hot Shot Pest Control Fogger is a spray-type insecticide designed to kill spiders and other insects on contact by releasing a fine mist that penetrates into cracks and hidden spaces. It uses active ingredients Tetramethrin and Cypermethrin, which are common and effective for pest control but should be handled carefully due to their chemical nature. Each can covers a large space of up to 2,000 cubic feet, making it suitable for treating rooms, garages, basements, and similar enclosed areas.

The fogger continues to kill pests for up to two months after application, offering lasting protection against infestations. Its clear, non-staining formula avoids messy residue, which is a plus for ease of use indoors. However, because it is a fogger, it requires vacating the treated area during application and proper ventilation afterward, which might not be convenient for all users. Safety-wise, it meets USDA specifications but involves chemicals that should be used with caution, especially around pets and children.

This product is best suited for people dealing with moderate to heavy indoor infestations who want a powerful and long-lasting solution rather than simple spider repellents. It may be less ideal for those seeking natural or non-chemical options or quick, small-scale treatments.