10 Best Stool Softener 2025 in the United States

The Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder is an osmotic laxative designed to relieve occasional constipation. Its active ingredient, Polyethylene Glycol 3350, is highly regarded and recommended by doctors, which is reassuring for those looking for a reliable stool softener. The product typically produces a bowel movement within 1 to 3 days, offering relief without urgent pressure.

One of its notable benefits is the ability to soften stools, making bowel movements more comfortable and frequent. The powder is unflavored, allowing it to be mixed into any beverage without altering the taste, which is convenient for those with taste sensitivities. Additionally, it is free from grit, sugar, and gluten, making it suitable for a variety of dietary needs.

The product is intended for adults and children aged 17 and older, which limits its use for younger children. As a part of Amazon's Basic Care line, it benefits from the brand's reputation for value and dependability. The product's size and weight make it easy to store and handle. While effective, it’s important to note that it might not be suitable for those looking for immediate relief due to its 1 to 3-day onset of action.

The GenCare Senna-S Natural Vegetable Laxative Plus Stool Softener is a dual-action product designed to provide overnight relief from occasional constipation. The active ingredients, sennosides (a natural vegetable laxative) and docusate sodium (a stool softener), work together to empty the bowels and soften stools, typically producing results within 6 to 12 hours when taken before bedtime.

This dual-action approach can be advantageous for those needing both stool softening and bowel stimulation simultaneously. Each tablet is easy to swallow, which makes it more user-friendly compared to suppositories or unpleasant-tasting liquids. Additionally, the 200-tablet value pack offers significant cost savings, making it a practical choice for families or individuals needing frequent use.

However, it's important to use the product as directed and consult a doctor for children under 2 years old. This product is best suited for those seeking an affordable and effective solution for occasional constipation relief.

The Colace Regular Strength Stool Softener 100 mg Capsules offer gentle and dependable relief from occasional constipation. The active ingredient, docusate sodium, works by allowing water and fats to penetrate the stool, making it softer and easier to pass. This product is stimulant-free, which means it doesn't cause sudden bowel movements, making it a comfortable and safe choice for those who need relief without harsh side effects. Its onset of action ranges from 12 to 72 hours, which provides flexibility but might be slower for those seeking immediate relief.

The recommended usage is occasional, which aligns well with its gentle formulation, making it suitable for pregnant and postpartum women, although they should consult a health professional before use. Colace is a well-known and reputable brand, and being the #1 doctor-recommended stool softener adds to its credibility. However, while the product is effective for occasional use, it might not be ideal for chronic constipation sufferers who might need a faster-acting or more potent solution.

The capsules are a convenient dosage form, but some users may prefer other forms like liquid or chewable tablets. The product's safety and effectiveness make it a strong choice for those seeking gentle relief from occasional constipation.