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10 Best Vertical Mouses 2025 in the United States

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Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

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Our Top Picks

#1

Winner

ASOYIOL Ergonomic Mouse Wireless,Vertical Mouse with USB Receiver 6 Buttons 800/1200/1600 Computer Mouse for Laptop PC(Right Hand,Black)

Rating
10.0
Chosen by1,311
Ergonomics
DPI (Dots Per Inch)
Buttons and Customization

Most important from
2094 reviews

Ergonomics
The vertical design feels natural and reduces wrist strain during long hours of use.
DPI (Dots Per Inch)
The adjustable DPI settings make it versatile and suitable for various tasks.
Buttons and Customization
The buttons are responsive and the precision is top-notch, perfect for both work and gaming.
Battery Life
The rechargeable battery lasts a long time, enhancing usability and convenience.

The ASOYIOL Ergonomic Mouse Wireless is designed for users who need a comfortable and strain-free experience. Its vertical ergonomic design is beneficial for reducing hand strain and promoting healthier hand positioning, making it a good option for daily computer use and gaming. With adjustable DPI settings of 1000, 1200, and 1600, it allows for precise tracking on various surfaces, which is useful for both regular tasks and gaming.

The mouse features six buttons, including 'Page Back' and 'Page Forward' functionalities, catering to users who need extra buttons for navigation or gaming purposes. Connectivity is straightforward using a USB receiver, though it doesn't support MacOS X, limiting its compatibility to Windows and Linux systems. The built-in rechargeable battery is convenient and includes a power-saving mode after 8 minutes of inactivity, enhancing battery life.

The mouse is lightweight and portable, weighing only 3.35 ounces. If you're looking for an ergonomic mouse for Windows or Linux systems, this model is a solid choice, although Mac users will need to look elsewhere.

Rating
10.0
Chosen by1,311
Ergonomics
DPI (Dots Per Inch)
Buttons and Customization

Most important from
2094 reviews

Ergonomics
The vertical design feels natural and reduces wrist strain during long hours of use.
DPI (Dots Per Inch)
The adjustable DPI settings make it versatile and suitable for various tasks.
Buttons and Customization
The buttons are responsive and the precision is top-notch, perfect for both work and gaming.
Battery Life
The rechargeable battery lasts a long time, enhancing usability and convenience.
#2

Evoluent Vertical Mouse D Large (VMDL) - Ergonomic Wired Mouse for Laptop and PC with Jestik Microfiber Cloth

Rating
10.0
Ergonomics

Most important from
11 reviews

Ergonomics
Switching to the Evoluent Vertical Mouse D Large eliminated wrist problems, with its nearly full vertical design offering significant ergonomic relief.

The Evoluent Vertical Mouse D Large (VMDL) is tailored for users seeking ergonomic solutions to minimize wrist strain, particularly beneficial for those working long hours at a computer. Its vertical design encourages a natural hand position, potentially reducing the risk of repetitive stress injuries. The unique grooved buttons offer a secure grip, enhancing control, which can be a comfort for users accustomed to traditional mouses.

One of the VMDL's standout features is its Smart Scrolling capability, allowing a fluid transition from precise to rapid scrolling, adapting to your pace. While it boasts programmable buttons and an integrated volume control, customization options may appeal to users who enjoy personalized setups for efficiency. As a wired mouse, it guarantees uninterrupted connectivity, but it lacks the flexibility of wireless options for those who prefer a clutter-free workspace.

Compatibility is broad, supporting both Windows and Mac systems, making it versatile for diverse computer users. However, while it functions without drivers, installing them unlocks advanced features, potentially adding complexity for less tech-savvy users. Despite its ergonomic appeal, the lack of DPI adjustment could be a downside for gamers or graphic designers who require precise sensitivity control. Also, as a wired device, it's not constrained by battery life, but the trade-off is tethered movement, which might not suit everyone.

Finally, the inclusion of a Jestik Microfiber Cloth is a thoughtful touch, helping maintain the mouse's cleanliness and longevity. With positive customer reviews and a notable ranking among computer mice, the Evoluent Vertical Mouse D Large presents itself as a solid choice for those prioritizing ergonomic design and consistent performance in a desktop setting.

Rating
10.0
Ergonomics

Most important from
11 reviews

Ergonomics
Switching to the Evoluent Vertical Mouse D Large eliminated wrist problems, with its nearly full vertical design offering significant ergonomic relief.
#3

J-Tech Digital Wired Ergonomic Vertical USB Mouse with Adjustable Sensitivity (600/1000/1600 DPI), Scroll Endurance, Removable Palm Rest & Thumb Buttons [V628]

Rating
10.0
Ergonomics
Battery Life

Most important from
7018 reviews

Ergonomics
The ergonomic design effectively eliminates wrist, elbow, and shoulder pain, making it a game-changer for those with existing discomfort.
Battery Life
The mouse is rechargeable, providing the convenience of not needing to replace batteries frequently.

The J-Tech Digital Wired Ergonomic Vertical USB Mouse is designed with a focus on comfort and reducing strain, making it a good choice for users with carpal tunnel syndrome or those who spend long hours on the computer. Its ergonomic 'handshake' design is effective in minimizing wrist and arm stress, and the removable palm rest adds to the comfort level.

The mouse offers adjustable DPI settings (600/1000/1600), allowing users to customize the sensitivity based on their preference and tasks, which is a useful feature for both everyday use and light gaming or graphic work. Connectivity is straightforward with a USB connection, ensuring compatibility with most computers without the need for additional drivers. However, being wired may limit some users who prefer the freedom of a wireless setup.

The back/forward thumb buttons add convenience for web browsing and other repetitive tasks, and these buttons can be customized with third-party software for enhanced functionality. One notable downside is the need for a lithium-ion battery, even though it's rechargeable, which means you'll need to remember to keep it charged. In terms of compatibility, it works well with both Windows and Mac systems, making it a versatile option. Despite a few drawbacks, such as being wired and the need for charging, the J-Tech Digital V628 stands out for its ergonomic design and customization options.

Rating
10.0
Ergonomics
Battery Life

Most important from
7018 reviews

Ergonomics
The ergonomic design effectively eliminates wrist, elbow, and shoulder pain, making it a game-changer for those with existing discomfort.
Battery Life
The mouse is rechargeable, providing the convenience of not needing to replace batteries frequently.

Buying Guide for the Best Vertical Mouses

Choosing the right vertical mouse can significantly improve your comfort and productivity, especially if you spend long hours working on a computer. Vertical mice are designed to reduce strain on your wrist and forearm by promoting a more natural hand position. When selecting a vertical mouse, it's important to consider several key specifications to ensure you get the best fit for your needs. Here are the main factors to consider and how to navigate them.
ErgonomicsErgonomics refers to how well the mouse fits your hand and supports a natural posture. This is crucial because a well-designed ergonomic mouse can help prevent repetitive strain injuries. When evaluating ergonomics, consider the size and shape of the mouse. Small hands may require a smaller mouse, while larger hands may need a bigger one. Additionally, look for features like a contoured shape and thumb rest, which can provide extra support and comfort. Test different models if possible to find the one that feels most comfortable for your hand size and grip style.
DPI (Dots Per Inch)DPI measures the sensitivity of the mouse. A higher DPI means the cursor will move further on the screen for each inch the mouse is moved. This is important for tasks that require precision, such as graphic design or gaming. DPI settings can range from 400 to over 4000. For general office work, a DPI between 800 and 1600 is usually sufficient. If you need more precision, look for a mouse with adjustable DPI settings so you can customize it to your needs.
ConnectivityConnectivity options include wired, wireless, and Bluetooth. Wired mice offer a stable connection and don't require batteries, making them a good choice for stationary setups. Wireless mice provide more freedom of movement and a cleaner desk setup but require batteries or charging. Bluetooth mice can connect to multiple devices and are ideal for users who switch between different computers or tablets. Consider your work environment and how you plan to use the mouse when choosing the best connectivity option for you.
Buttons and CustomizationThe number and placement of buttons can affect your productivity. Standard mice have two buttons and a scroll wheel, but vertical mice often come with additional buttons that can be customized for specific functions. This is useful for tasks that involve repetitive actions, such as copy-pasting or navigating through documents. Look for a mouse with programmable buttons if you want to streamline your workflow. Make sure the buttons are easily accessible and comfortable to use.
Battery LifeFor wireless and Bluetooth mice, battery life is an important consideration. Some mice use replaceable batteries, while others have rechargeable ones. Battery life can range from a few weeks to several months, depending on usage and the type of battery. If you prefer a low-maintenance option, look for a mouse with long battery life or one that can be easily recharged. Consider how often you use the mouse and whether you have a convenient way to recharge it when needed.
CompatibilityEnsure that the mouse is compatible with your operating system and any specific software you use. Most mice are compatible with both Windows and macOS, but it's always good to check. Some advanced features or customization options may require specific software that is only available for certain operating systems. Verify compatibility to avoid any issues with functionality.

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