10 Best Bed Bugs Sprays 2025 in the United States

The Ortho Home Defense Max Bed Bug Killer is a strong choice for tackling bed bugs, including those resistant to common chemicals. Its active ingredients effectively kill bed bugs and their eggs, as well as fleas and ticks, making it useful against multiple pests. A big plus is its long-lasting effect, continuing to kill bugs for up to 16 weeks on hard surfaces like ceramic, which helps prevent re-infestation.

The spray is designed for spot treatment around beds, floors, and furniture, which is convenient for targeted use without widespread application. It comes unscented, so it won’t leave an unpleasant smell in your home—a nice feature for sensitive users. Customers generally rate it well, praising its effectiveness and ease of use. The residual effect mainly works on non-porous surfaces, so results might not last as long on carpets or fabrics.

While it promises safety, users should still follow instructions carefully to avoid exposure, as with any pesticide. For those seeking a product that kills quickly and provides weeks of protection on hard surfaces, this spray fits the bill, especially when combined with Ortho’s other bed bug products for detection and powder treatment.

The Ortho Home Defense Max Bed Bug, Flea and Tick Killer is designed to tackle stubborn bed bugs, including those resistant to common treatments, as well as their eggs, fleas, and ticks. A key strength is its Comfort Wand, which makes the spray easy to apply, especially in hard-to-reach spots around bed frames and baseboards, contributing to its ease of use. The product is part of a comprehensive 3-step solution, which may appeal to those seeking a systematic approach to pest control. Additionally, with a sizable 1-gallon volume, it offers substantial coverage.

In terms of safety, like many pest control products, it is important to exercise caution and follow label instructions carefully to minimize any potential risks. The spray is labeled for indoor use, but users sensitive to chemical odors should note its 'Tick' scent. While not overwhelmingly strong based on user feedback, it is present, which could be a downside for those preferring odorless solutions.

The spray is effective, particularly in combating pyrethroid-resistant bed bugs, a challenging pest. However, achieving optimal results often requires its use in conjunction with the other steps in the Ortho Bed Bug Solution System. This might be seen as a drawback for those looking for a standalone solution.

The EcoRaider Bed Bug Killer Spray is a strong contender in the market for bed bug eradication, particularly for those concerned with safety and eco-friendliness. Its active ingredients are non-toxic and eco-friendly, making it safe to use around children and pets and even on mattresses and box springs. The product has been proven to kill bed bugs at all life stages, including those resistant to traditional pesticides, with a 100% efficacy rate according to a university study published in the Journal of Economic Entomology. This gives it a clear advantage for those dealing with stubborn infestations.

Additionally, its extended dry residual protection offers continued effectiveness for up to two weeks after application, ensuring longer-term results. However, some users might find the odor of the spray somewhat prominent, although it is not described as harsh or chemical-smelling. The ease of use is fairly straightforward, but handling a gallon jug can be cumbersome for some.

It ranks well in customer satisfaction, holding a 4.4-star rating out of over 3,000 reviews, indicating that most users find it effective and worth the investment. Summing up, if you are looking for a potent, safe, and eco-friendly solution to bed bugs, the EcoRaider Bed Bug Killer Spray deserves consideration.