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10 Best Bedbug Sprays 2025 in the United States

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Our Top Picks

#1

Winner

Ortho Home Defense Max Bed Bug Killer - Also Kills Fleas & Brown Dog Ticks, Spot Treatment, 18 oz. (2-Pack)

Rating
9.9
Chosen by1,158
Residual Effect
Application Method
Odor

Most important from
29802 reviews

Residual Effect
The product’s residual effect keeps pests at bay for weeks, making it a reliable choice for long-term control, especially on hard surfaces.
Application Method
Consistent and thorough application, including treating cracks, furniture, mattresses, and even outside vents, is crucial for fully eradicating bed bugs.
Odor
Its unscented or pleasant mild smell is a welcome change from harsh chemical odors commonly found in pest sprays.
Effectiveness on Different Life Stages
While highly effective, repeated applications over weeks may be necessary to address all life stages of pests, especially in heavy infestations.

The Ortho Home Defense Max Bed Bug Killer spray is designed to tackle bed bugs effectively, including those resistant to common pyrethroid insecticides. It kills both the bugs and their eggs, which is important since eggs are often hardest to eliminate. One standout feature is its residual effect: it continues killing bed bugs for up to 16 weeks on hard surfaces like ceramic, providing longer-lasting protection compared to some sprays that lose effectiveness quickly.

Its application is straightforward as a spot treatment, ideal for use around bed frames, headboards, floors, and carpets where bed bugs hide. The spray is unscented, which is good if you prefer no strong chemical odors in your home. It also targets other pests such as fleas, ticks, and various household bugs, adding extra value. Safety-wise, while the product is effective, it contains chemical ingredients and should be used carefully according to instructions, especially around pets and children.

A minor drawback is that it works best on non-porous surfaces; its long-lasting effect may be less on porous materials like fabric or wood. For best results, it is recommended to use this spray along with Ortho’s bed bug traps and powder treatments for a more complete control strategy. If you want a reliable, multi-purpose bed bug spray with a strong residual action and no odor, this product is a good choice. However, it functions best as part of a combined approach rather than a one-step solution.

Rating
9.9
Chosen by1,158
Residual Effect
Application Method
Odor

Most important from
29802 reviews

Residual Effect
The product’s residual effect keeps pests at bay for weeks, making it a reliable choice for long-term control, especially on hard surfaces.
Application Method
Consistent and thorough application, including treating cracks, furniture, mattresses, and even outside vents, is crucial for fully eradicating bed bugs.
Odor
Its unscented or pleasant mild smell is a welcome change from harsh chemical odors commonly found in pest sprays.
Effectiveness on Different Life Stages
While highly effective, repeated applications over weeks may be necessary to address all life stages of pests, especially in heavy infestations.
#2

Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.

Rating
9.8
Application Method
Odor

Most important from
29802 reviews

Application Method
The Comfort Wand allows for precise application in tight spaces, making the process simple and effective.
Odor
The spray is odorless, a remarkable feature compared to other brands with strong smells.

The Ortho Home Defense Max Bed Bug, Flea, and Tick Killer is a powerful option for anyone dealing with bed bugs, fleas, and ticks. One of its key strengths is its ability to kill even pyrethroid-resistant bed bugs, making it suitable for handling tough infestations. The inclusion of the Comfort Wand is a thoughtful addition, allowing users to target hard-to-reach areas like mattress seams and baseboards effectively. This feature makes the application process easier and more precise.

The product is also versatile, addressing not just bed bugs, but their eggs, fleas, and ticks as well, which could save you from needing multiple sprays for different pests. However, one potential drawback is the odor associated with the spray, which some users might find unpleasant. On the plus side, user reviews are generally favorable, with a 4.4 out of 5-star rating from over 28,000 reviews, indicating a high level of effectiveness and customer satisfaction.

In terms of safety, as with many pest control products, it’s important to use it as directed to avoid any potential health risks, especially if you have pets or children. Finally, the spray’s 1-gallon volume offers good value, especially if you’re treating multiple areas or need to reapply over time. While it is part of a larger Ortho Bed Bug Solution System, it seems quite effective on its own for most users. This makes it a solid choice for households needing a reliable solution against bed bugs, fleas, and ticks.

Rating
9.8
Application Method
Odor

Most important from
29802 reviews

Application Method
The Comfort Wand allows for precise application in tight spaces, making the process simple and effective.
Odor
The spray is odorless, a remarkable feature compared to other brands with strong smells.
#3

Hot Shot Ready-to-Use Bed Bug Killer Spray, Kills Bed Bugs and Bug Eggs Indoors, Kills Fleas and Dust Mites, Non-Staining, 1 Gallon

Rating
9.6
Application Method
Effectiveness on Different Life Stages

Most important from
21626 reviews

Application Method
Easy to use and follow instructions, which ensures optimal results.
Effectiveness on Different Life Stages
Effective in eliminating fleas when used correctly, especially in combination with other treatments like grooming pets.

The Hot Shot Ready-to-Use Bed Bug Killer Spray is designed to target and eliminate bed bugs and their eggs, as well as fleas and dust mites. Its water-based formula ensures that it won’t stain surfaces and leaves no odor, making it a practical choice for indoor use. The spray is easy to apply to specific areas like mattress tufts, folds, and seams, but it's important to spray until damp without saturating the area.

Reapplication every two weeks is recommended to maintain control over bed bugs, as part of a comprehensive treatment plan. This means users need to be diligent and consistent for the best results, which may be a drawback for those seeking a one-time solution. Safety-wise, it should not be used on pets, which is a common restriction among such products.

The product is well-rated with a 4.2 out of 5-star average from over 21,000 reviews, indicating general satisfaction among users. Those sensitive to chemical sprays might want to consider its safety and toxicity levels. In summary, Hot Shot’s bed bug spray is effective for various life stages of bed bugs and other pests, but requires repeated applications and careful adherence to usage instructions for optimal results.

Rating
9.6
Application Method
Effectiveness on Different Life Stages

Most important from
21626 reviews

Application Method
Easy to use and follow instructions, which ensures optimal results.
Effectiveness on Different Life Stages
Effective in eliminating fleas when used correctly, especially in combination with other treatments like grooming pets.

Buying Guide for the Best Bedbug Sprays

Choosing the right bedbug spray can be crucial in effectively dealing with an infestation. Bedbug sprays come in various formulations and strengths, and selecting the right one depends on your specific needs and circumstances. Understanding the key specifications of bedbug sprays will help you make an informed decision and ensure that you get a product that works effectively for your situation.
Active IngredientsThe active ingredients in a bedbug spray are the chemicals responsible for killing the bedbugs. Common active ingredients include pyrethroids, neonicotinoids, and desiccants. Pyrethroids are synthetic chemicals that act quickly but may not be effective against resistant bedbugs. Neonicotinoids affect the nervous system of bedbugs and can be effective against resistant strains. Desiccants work by drying out the bedbugs. Choose an active ingredient based on the severity of your infestation and any known resistance issues.
Residual EffectThe residual effect refers to how long the spray continues to kill bedbugs after application. Some sprays offer immediate results but have a short residual effect, while others may continue to work for weeks or even months. If you need long-term protection, look for sprays with a longer residual effect. For quick knockdown of an active infestation, a spray with a shorter residual effect may be sufficient.
Safety and ToxicitySafety and toxicity are important considerations, especially if you have children, pets, or sensitive individuals in your home. Some bedbug sprays are made with natural or less toxic ingredients, making them safer for use around people and animals. Always read the label and follow the safety instructions. If safety is a primary concern, opt for a product with lower toxicity.
Application MethodBedbug sprays come in various application methods, including aerosol sprays, pump sprays, and ready-to-use bottles. Aerosol sprays are convenient for reaching into cracks and crevices, while pump sprays may offer more control over the amount of product used. Ready-to-use bottles are straightforward and easy to apply. Choose an application method that suits your comfort level and the specific areas you need to treat.
OdorThe odor of a bedbug spray can be a significant factor, especially if you are sensitive to smells or plan to use the spray in living areas. Some sprays have a strong chemical odor, while others are formulated to be odorless or have a more pleasant scent. If odor is a concern, look for products labeled as low-odor or odorless.
Effectiveness on Different Life StagesBedbugs go through various life stages, from eggs to nymphs to adults. Some sprays are effective only against certain stages, while others can kill bedbugs at all stages of their life cycle. For comprehensive control, choose a spray that targets eggs, nymphs, and adults. This ensures that you can break the life cycle and prevent re-infestation.

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