10 Best Dog Toothpastes 2025 in the United States

The Virbac C.E.T. Enzymatic Toothpaste is designed to provide effective dental care for both dogs and cats while ensuring a fresh breath and healthy mouth. One of its standout features is the enzymatic formula, which helps reduce plaque and tartar buildup, a key concern for pet owners looking to maintain their pets' oral hygiene.

The Vanilla Mint flavor is appealing and can make the brushing experience more enjoyable for pets, encouraging regular use. This toothpaste is also safe for daily use as it doesn’t contain foaming agents, meaning pets can swallow it without any issues. Its approval by veterinary professionals adds a layer of trust for pet owners, making it a reliable choice in the market.

The product is available in a convenient 2.5 oz tube, making it easy to handle and store. However, it’s important to note that this toothpaste should be used with a soft-bristled toothbrush, which may require an extra purchase if you don’t already own one. Some users may also find that their pets need a bit of time to get used to the brushing routine.

Petsmile Professional Pet Toothpaste stands out in the dog toothpaste category due to its veterinary approval and high-quality, human-grade ingredients. The Veterinary Oral Health Council (VOHC) endorsement assures pet owners that it meets strict standards for oral health, making it a trusted choice for maintaining your pet's dental hygiene. Its proprietary formula, Calprox, is clinically proven to effectively prevent plaque, tartar, and gingivitis while whitening teeth, which is a significant benefit for pet owners looking to improve their animal's dental health.

One of the key advantages of Petsmile toothpaste is its no-brushing formula. This feature is particularly beneficial for pets that may be resistant to traditional brushing, as all you need to do is apply the toothpaste and let your pet use their tongue. Plus, the enticing London Broil flavor is likely to appeal to dogs, making dental care feel less like a chore. It’s safe for pets to eat right after application, which adds to its convenience.

However, it’s important to note that this toothpaste is non-enzymatic, which may be a disadvantage for pet owners specifically looking for enzymatic formulas that can actively break down plaque. Additionally, while the flavor is appealing to dogs, some cats may not find it as palatable, which could make it less effective for feline dental care. In terms of texture, the paste is designed to be easy to apply but may not be suitable for pets that prefer a more traditional toothpaste consistency. Also, while the safety of the ingredients is a plus, some consumers might still prefer products with more organic or natural certifications.

Petsmile Professional Pet Toothpaste offers a comprehensive solution for maintaining your pet's dental health. One of its most notable strengths is that it's the only VOHC-recommended pet toothpaste, indicating it meets high veterinary standards. Its proprietary Calprox formula is clinically proven to prevent plaque, tartar, and gingivitis, ensuring your pet's teeth stay clean and their breath fresh. Additionally, the toothpaste uses human-grade ingredients, which means it's safe for your pet to eat or drink immediately after use.

The London Broil flavor is likely to appeal to pets, making the application process easier for pet owners. Another convenient aspect is that it doesn't require brushing; you can simply apply it to your pet's teeth, and their tongue does the rest. This feature is particularly beneficial for owners of fussy pets. However, the non-enzymatic nature of this toothpaste is worth noting as enzymatic toothpastes are often recommended for their additional plaque-fighting benefits.

Moreover, while the ingredients are high-quality and hypoallergenic, some pet owners might prefer a toothpaste with organic or natural ingredients. The product's relatively high price point could also be a consideration for budget-conscious pet owners. Nonetheless, its strong veterinary endorsement and ease of use make it a solid choice for enhancing your pet's oral hygiene.