10 Best Dog Toothpastes 2025 in the United States

Vet’s Best Enzymatic Dog Toothpaste is a solid choice for dog owners seeking a vet-formulated dental care solution. It contains a blend of soothing and effective ingredients such as aloe, neem oil, grapefruit seed extract, baking soda, and enzymes. These components help clean teeth, remove plaque and tartar, and freshen breath, making it a comprehensive dental hygiene product for dogs. The enzymatic formula is particularly effective in breaking down plaque and maintaining oral health between professional cleanings.

The toothpaste is available in a unique banana flavor, which many dogs seem to enjoy, making the brushing process easier for both pets and owners. However, it’s worth noting that some dogs might not be fond of the banana flavor, which could make regular use challenging for those particular pets. The gel texture is designed for easy application, either with a brush or by rubbing it directly onto the teeth with a finger. This flexibility can accommodate different preferences and comfort levels of both dogs and owners.

One of the strengths of this product is its veterinary approval, ensuring that it meets certain standards for pet health and safety. It’s also paraben-free, which is a plus for pet owners concerned about potentially harmful additives. On the downside, the toothpaste requires no food or water for half an hour before and after application, which could be inconvenient for some pet owners. Despite this minor drawback, Vet’s Best Enzymatic Dog Toothpaste stands out as an effective and user-friendly option for maintaining your dog’s dental health.

Petsmile Professional Pet Teeth Brushing Kit is a well-regarded choice for pet owners wanting effective dental care for their dogs and cats. It stands out as the only toothpaste accepted by the Veterinary Oral Health Council (VOHC), which means it meets trusted standards to help control plaque and tartar buildup. Its special Calprox formula gently breaks down the protein layer on teeth, whitening them and improving gum health without harsh abrasives.

This toothpaste uses human-grade, hypoallergenic ingredients, making it safe for pets to eat or drink right after brushing, which adds ease and peace of mind. The flavor, London Broil, is unique among pet toothpastes and may appeal to pets, though some might be picky about flavors. The texture is a paste that works well with the included dual-ended toothbrush designed to clean below the gum line where plaque tends to hide. This brush’s angled head helps reach tricky spots, making daily brushing more effective.

The price point is generally higher than some other pet toothpastes, which may be a consideration for budget-conscious owners. Also, while the London Broil flavor is novel, it might not suit every pet’s taste preferences, so some trial may be needed. Petsmile provides a high-quality, vet-approved dental solution that combines safety, effectiveness, and thoughtful design—ideal for pet owners serious about maintaining their pet’s oral health with daily brushing.

Petsmile Professional Pet Tooth Brushing Kit offers a comprehensive solution for your pet's dental hygiene. One of its biggest strengths is veterinary approval; it is VOHC (Veterinary Oral Health Council) accepted, indicating it meets high standards in improving oral health. The toothpaste is clinically proven to prevent plaque, tartar, and gingivitis, thanks to its proprietary Calprox formula. This non-enzymatic paste also works to whiten teeth by gently dissolving the protein pellicle.

The human-grade ingredients ensure it’s safe for pets immediately after use, and its hypoallergenic formula is free from bisphenol A, sulfates, gluten, and parabens, adding to its appeal for health-conscious pet owners. The flavor is rotisserie chicken, which many pets may find appealing, making the brushing process easier. The dual-ended toothbrush with a 45° angled brush head is designed to clean below the gum line effectively.

However, there are a few points to consider. The toothpaste is non-enzymatic, which might be a downside for those specifically looking for enzymatic formulas. Additionally, the product size is relatively small at 2.5 ounces, which may not be ideal for those with larger pets or multiple pets. The flavor, while appealing to some pets, might not be universally loved by all. Nonetheless, with its strong veterinary endorsements, high-quality ingredients, and effective formula, Petsmile Professional Pet Tooth Brushing Kit is a solid choice for maintaining your pet's dental health.