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10 Best Enzyme Pet Cleaner 2025 in the United States

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Our Top Picks

#1

Winner

Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 1 Gallon

Rating
9.9
Chosen by1,158
Scent
Application Method

Most important from
7657 reviews

Scent
People walked into my house and complimented how good it smelled; this has never happened before with any other product.
Application Method
A little goes a long way; you don't need to soak the area – just spray and pat.

The ANGRY ORANGE Pet Odor Eliminator is a powerful solution for tackling strong pet odors, especially from dog urine. Its enzyme-based formula effectively breaks down and neutralizes lingering smells, making it a robust choice for pet owners dealing with persistent odor issues.

The citrus scent, derived from fresh orange peels, leaves a pleasant fragrance in the treated areas, enhancing the cleaning experience. This product is highly versatile, suitable for use on multiple surfaces including carpets, tiles, couch upholstery, garbage cans, car interiors, and even turf, which makes it convenient for a variety of cleaning needs around the house or car.

The application method is straightforward – simply remove pets from the area, clean up excess mess, shake well, spray, and let it dry completely. This ensures that the product can penetrate and eliminate odors effectively. However, the drying time might vary depending on the surface and amount used, which could be a minor inconvenience for some users. Additionally, while the gallon size is great for refilling smaller spray bottles, it might be cumbersome to handle directly for some people. Safety-wise, it’s important to follow the instructions to remove pets from the area during application to avoid any potential reactions.

ANGRY ORANGE also offers a responsive customer service team, which is a plus if you encounter any issues or have questions about the product. This pet odor eliminator is a strong contender for anyone facing tough pet odors, though some minor considerations regarding drying time and handling the larger container should be kept in mind.

Rating
9.9
Chosen by1,158
Scent
Application Method

Most important from
7657 reviews

Scent
People walked into my house and complimented how good it smelled; this has never happened before with any other product.
Application Method
A little goes a long way; you don't need to soak the area – just spray and pat.
#2

ANGRY ORANGE Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 24 oz - Value 2 Pack

Rating
9.8
Enzyme Type
Scent
Application Method

Most important from
116664 reviews

Enzyme Type
Even professional cleaners couldn't remove the odor as effectively as Angry Orange.
Scent
This product truly eliminates the smell of cat urine, and the odor doesn't return.
Application Method
A little goes a long way; you don't need to use much to get the job done.

The ANGRY ORANGE Pet Odor Eliminator is designed to tackle tough pet odors and stains on various surfaces, particularly hard and sealed floors. This cleaner uses natural orange oil, providing a pleasant citrus scent that doesn't rely on harsh chemicals. The scent lasts for up to 12 hours, making it effective for prolonged freshness. It comes in a spray form, making it easy to apply manually to the affected areas.

One of its key strengths is its safety features, as it is free from parabens, sulfates, and phthalates, making it suitable for homes with pets when used as directed. Additionally, it is manufactured in the USA, ensuring good quality standards. This cleaner is best suited for pet owners dealing with strong odors and stains on hard floors, who prefer a natural citrus scent and prioritize safety in their cleaning products.

Rating
9.8
Enzyme Type
Scent
Application Method

Most important from
116664 reviews

Enzyme Type
Even professional cleaners couldn't remove the odor as effectively as Angry Orange.
Scent
This product truly eliminates the smell of cat urine, and the odor doesn't return.
Application Method
A little goes a long way; you don't need to use much to get the job done.
#3

Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

Rating
9.7
Enzyme Type
Surface Compatibility
Scent

Most important from
119203 reviews

Enzyme Type
The enzyme-activated formula not only removes stains but also completely eliminates odors, preventing pets from remarking the same spot.
Surface Compatibility
Works wonders on various surfaces including carpets, hardwood, and furniture without leaving any residue or damage.
Scent
The pleasant, non-chemical scent of the cleaner leaves your home smelling fresh and clean.
Safety
Safe for use around pets and children, this product tackles the toughest pet messes without harmful chemicals.

Rocco & Roxie Supply Co. Stain & Odor Eliminator is an enzyme-based cleaner designed specifically for pet-related stains and odors, making it an excellent choice for pet owners dealing with messes from cats and dogs. One of its key strengths is its enzyme-activated formula, which effectively targets and breaks down the organic matter in pet urine, feces, and vomit, ensuring not just the removal of stains but also the elimination of odors. It's certified safe for use around pets and children, as it is chlorine-free and leaves no harmful residues, which is a significant plus for households with little ones or furry friends.

The cleaner is versatile, compatible with multiple surfaces including carpets, floors, and furniture, which adds to its usability. It has a pleasant original scent that helps freshen up areas after cleaning.

However, there are some drawbacks to consider. Some users may find that the drying time can vary, and it might not be as effective on very old or set-in stains. Additionally, while the product claims to work on various surfaces, it is always wise to perform a patch test before using it on delicate materials, as reactions can vary. Lastly, the satisfaction guarantee offered by the company enhances customer confidence in their purchase, although it is limited to purchases from authorized sellers.

Rating
9.7
Enzyme Type
Surface Compatibility
Scent

Most important from
119203 reviews

Enzyme Type
The enzyme-activated formula not only removes stains but also completely eliminates odors, preventing pets from remarking the same spot.
Surface Compatibility
Works wonders on various surfaces including carpets, hardwood, and furniture without leaving any residue or damage.
Scent
The pleasant, non-chemical scent of the cleaner leaves your home smelling fresh and clean.
Safety
Safe for use around pets and children, this product tackles the toughest pet messes without harmful chemicals.

Buying Guide for the Best Enzyme Pet Cleaner

Choosing the right enzyme pet cleaner can make a significant difference in maintaining a clean and odor-free home, especially if you have pets. Enzyme cleaners are designed to break down organic materials like urine, feces, vomit, and other pet-related messes, making them highly effective for cleaning and deodorizing. When selecting an enzyme pet cleaner, it's important to consider several key specifications to ensure you get the best product for your needs.
Enzyme TypeEnzyme type refers to the specific enzymes used in the cleaner. Different enzymes target different types of organic matter. For example, proteases break down proteins, amylases break down starches, and lipases break down fats. It's important because the effectiveness of the cleaner depends on the type of mess you're dealing with. If you primarily need to clean up urine, look for a cleaner with urease enzymes. For a variety of messes, a cleaner with a combination of enzymes is ideal. Choose based on the common types of stains and odors you encounter.
Surface CompatibilitySurface compatibility indicates which surfaces the cleaner can be safely used on, such as carpets, upholstery, hardwood floors, or tiles. This is important because using the wrong cleaner on a surface can cause damage or discoloration. Cleaners are often labeled for specific surfaces, so check the product description to ensure it matches your needs. If you have multiple types of surfaces, look for a versatile cleaner that is safe for all of them. Choose based on the surfaces you need to clean most frequently.
ScentThe scent of the cleaner can affect the overall experience of using the product. Some enzyme cleaners have a strong fragrance to mask odors, while others are unscented or have a mild scent. This is important because a strong scent might be overwhelming or unpleasant for some people and pets. If you or your pets are sensitive to strong smells, opt for an unscented or lightly scented cleaner. Choose based on your preference for fragrance and sensitivity to smells.
Application MethodThe application method refers to how the cleaner is applied, such as spray, pour, or foam. This is important because it affects ease of use and effectiveness. Sprays are convenient for spot cleaning, while pour bottles might be better for larger areas. Foam can penetrate deeper into carpets and upholstery. Consider how you will be using the cleaner and choose the application method that suits your cleaning habits. Choose based on the size and type of messes you typically clean.
Drying TimeDrying time is the amount of time it takes for the cleaner to dry after application. This is important because a longer drying time might be inconvenient, especially in high-traffic areas. Some cleaners dry quickly, while others may take several hours. If you need to use the cleaned area soon after application, look for a cleaner with a shorter drying time. Choose based on how quickly you need the area to be usable again.
SafetySafety refers to whether the cleaner is non-toxic and safe for pets and humans. This is important because some cleaners contain harsh chemicals that can be harmful if ingested or if they come into contact with skin. Look for products labeled as non-toxic, biodegradable, and safe for pets and children. Choose based on the safety needs of your household, especially if you have young children or pets who might come into contact with the cleaned areas.

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