10 Best Enzyme Pet Cleaner 2025 in the United States

Rocco & Roxie Supply Co. Stain & Odor Eliminator is an enzyme-based cleaner designed specifically for pet-related stains and odors, making it an excellent choice for pet owners dealing with messes from cats and dogs. One of its key strengths is its enzyme-activated formula, which effectively targets and breaks down the organic matter in pet urine, feces, and vomit, ensuring not just the removal of stains but also the elimination of odors. It's certified safe for use around pets and children, as it is chlorine-free and leaves no harmful residues, which is a significant plus for households with little ones or furry friends.

The cleaner is versatile, compatible with multiple surfaces including carpets, floors, and furniture, which adds to its usability. It has a pleasant original scent that helps freshen up areas after cleaning.

However, there are some drawbacks to consider. Some users may find that the drying time can vary, and it might not be as effective on very old or set-in stains. Additionally, while the product claims to work on various surfaces, it is always wise to perform a patch test before using it on delicate materials, as reactions can vary. Lastly, the satisfaction guarantee offered by the company enhances customer confidence in their purchase, although it is limited to purchases from authorized sellers.

The Rocco & Roxie Extreme Stain & Odor Eliminator is a powerful enzyme-based cleaner designed to tackle tough pet messes like urine, vomit, and feces. It uses a bio-enzymatic formula combined with a mineral odor neutralizer, which works by breaking down organic stains and odors at their source. It’s safe for use on many surfaces including carpets, floors, furniture, pet bedding, and even car interiors, making it a versatile choice for homes with pets.

The liquid spray has a light lemon scent that fades quickly, so it freshens without leaving a strong smell behind. It is free from chlorine and toxic chemicals, so it’s safe to use around pets and children when used as directed. The product dries reasonably fast, leaving no residue, and has earned approval from the Carpet and Rug Institute for safety on carpets.

One potential drawback is that the product is primarily marketed for carpets, so its effectiveness on some delicate fabrics or specialty surfaces may vary. Also, while it’s highly rated by users for odor removal, some might find the 32-ounce bottle size a bit small for very large areas. If you want a reliable, enzyme-based solution that’s gentle yet tough on pet stains and odors, this cleaner is a solid option that balances safety and performance well.

The ANGRY ORANGE Pet Odor Eliminator is a powerful solution for tackling strong pet odors, especially from dog urine. Its enzyme-based formula effectively breaks down and neutralizes lingering smells, making it a robust choice for pet owners dealing with persistent odor issues.

The citrus scent, derived from fresh orange peels, leaves a pleasant fragrance in the treated areas, enhancing the cleaning experience. This product is highly versatile, suitable for use on multiple surfaces including carpets, tiles, couch upholstery, garbage cans, car interiors, and even turf, which makes it convenient for a variety of cleaning needs around the house or car.

The application method is straightforward – simply remove pets from the area, clean up excess mess, shake well, spray, and let it dry completely. This ensures that the product can penetrate and eliminate odors effectively. However, the drying time might vary depending on the surface and amount used, which could be a minor inconvenience for some users. Additionally, while the gallon size is great for refilling smaller spray bottles, it might be cumbersome to handle directly for some people. Safety-wise, it’s important to follow the instructions to remove pets from the area during application to avoid any potential reactions.

ANGRY ORANGE also offers a responsive customer service team, which is a plus if you encounter any issues or have questions about the product. This pet odor eliminator is a strong contender for anyone facing tough pet odors, though some minor considerations regarding drying time and handling the larger container should be kept in mind.