10 Best Pet Urine Odor Removers 2025 in the United States

Rocco & Roxie Extreme Stain & Odor Eliminator is a strong enzyme-based cleaner designed to tackle tough pet stains and odors, including urine, vomit, and feces. Its bio-enzymatic formula actively breaks down organic messes and ammonia crystals, which makes it particularly effective for deep cleaning and odor removal. This product works well on a wide range of surfaces like carpets, furniture, pet bedding, floors, and even travel crates, making it versatile for various accidents around the home or car. The light Meyer lemon scent is subtle and fades quickly, so it doesn’t leave an overpowering fragrance behind.

Application is simple with the spray format, allowing you to target problem areas directly. It dries reasonably fast, helping you get back to normal use without long wait times. Safety is a key benefit here—it's free from chlorine and harmful propellants, and it’s certified safe for use around pets and children, including having a seal of approval from the Carpet and Rug Institute, meaning it's gentle on carpets and colors.

Some users might find the 32-ounce bottle size a bit small if cleaning large areas frequently, and while it's effective on many surfaces, always test on delicate fabrics first to avoid any unexpected reactions. The product has high customer satisfaction, reflecting its reliable performance. This cleaner suits pet owners looking for a dependable, safe, and easy-to-use solution for strong odors and stains, especially if you want a product that’s safe for pets and children with minimal scent.

ANGRY ORANGE 1 Gallon Enzyme Cleaner is designed specifically to tackle tough pet stains and odors caused by dog and cat urine, feces, and vomit. Its enzyme-based formula actively breaks down stain molecules rather than just covering them up, which is important for truly eliminating odors. This product stands out for its versatility, working on a wide range of surfaces such as carpets, upholstery, tile, car interiors, and even outdoor areas like patios and turf. The citrus scent leaves a fresh, natural smell after cleaning, which many users find more pleasant than harsh chemical odors.

Application is straightforward: simply spray on the affected area after removing any solid waste and let the enzymes do their work. Being a gallon refill, it's a cost-effective choice for frequent use or larger cleaning jobs. It’s also non-toxic and made in the USA, which adds to its safety profile for homes with pets and children. Some users might find the drying time a bit longer compared to other cleaners, especially if applied heavily, so it’s best to allow the treated area to air dry fully. While it’s generally safe on many surfaces, testing on a small hidden spot is recommended to avoid potential discoloration, particularly on delicate fabrics.

Angry Orange is a reliable option for pet owners who need a powerful, multi-surface enzyme cleaner with a fresh scent and solid safety features.

Nature’s Miracle Advanced Stain And Odor Eliminator is designed to tackle tough pet messes using an enzymatic formula that breaks down stains and odors at their source, which helps prevent pets from returning to the same spot. It’s suitable for a variety of surfaces including carpets, hard floors, furniture, and clothing, making it a versatile choice for households with pets. The product comes with a light, fresh scent, which is pleasant without being overpowering, helping to freshen your home as it cleans. It dries fairly quickly, allowing you to get back to normal use of the treated area sooner.

Safety-wise, it is formulated for use around pets and adults, but as with most cleaning products, basic precautions like keeping it out of reach of children and pets until dry are advisable. While effective on severe messes, the liquid form means you’ll need to apply and possibly blot the area, which may require some effort for large stains. Additionally, the fresh scent might not appeal to everyone, especially if you prefer fragrance-free options. This product is a practical and efficient choice for pet owners dealing with strong urine odors and stains, especially if you want a solution that works on multiple surfaces and leaves a light scent behind.