10 Best Pet Urine Odor Removers 2025 in the United States

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator is a popular enzyme-based cleaner designed specifically to tackle tough pet stains and odors, including cat and dog urine. Its formula is gentle and safe, free from chlorine and harmful chemicals, making it suitable for use around pets and children. The product holds a Carpet and Rug Institute Seal of Approval, indicating it is safe for all carpet types. It works on a wide range of surfaces beyond carpets, such as floors, furniture, clothing, litter boxes, and pet carriers, which makes it quite versatile. The original scent is mild and not overpowering, which many users appreciate. Application is straightforward—shake gently before use and blot stains before applying the spray. While the drying time is not explicitly mentioned, enzyme cleaners like this generally dry within a reasonable period without leaving residue. One of its strengths is the manufacturer’s satisfaction guarantee, providing confidence in the purchase.

On the downside, the product comes in a large 1-gallon bottle, which might be bulky for some and less convenient for small quick cleanups. Also, enzyme cleaners sometimes require patience as odor removal may take a few treatments depending on the severity of the stain. This cleaner is an excellent choice for pet owners looking for a safe, effective, and multi-surface solution to remove urine stains and odors from their home.

Angry Orange Pet Odor Eliminator is a strong choice for pet owners dealing with dog and cat urine smells and stains. It uses natural orange oil instead of harsh chemicals, which helps break down odors effectively while leaving behind a fresh citrus scent that many find pleasant rather than overpowering. This product works well on hard and sealed surfaces commonly affected by pet messes, such as floors and carpets, making it versatile for various household areas.

While it doesn’t specifically mention being enzyme-based, its natural oil formula effectively tackles odor at the source without the chemical stink associated with some odor removers. Being a spray in a large 1-gallon bottle, it allows for easy application and refilling smaller bottles, though it might take some time to dry depending on the surface and amount used. Safety is a strong point here, as the product contains no parabens, sulfates, or phthalates and is safe for use around pets when directions are followed, which reassures pet owners about potential toxicity concerns.

One downside is that it’s designed primarily for hard and sealed surfaces, so it may not be ideal for all carpet types or fabrics without testing first. Also, the heavy gallon size is better suited for home use rather than travel or quick touch-ups. Angry Orange serves as a reliable, naturally scented option that balances effective odor elimination with pet safety, especially for those who prefer non-toxic, chemical-free cleaners for household pet messes.

Rocco & Roxie Extreme Stain & Odor Eliminator is a strong enzyme-based cleaner designed to tackle tough pet stains and odors, including urine, vomit, and feces. Its bio-enzymatic formula actively breaks down organic messes and ammonia crystals, which makes it particularly effective for deep cleaning and odor removal. This product works well on a wide range of surfaces like carpets, furniture, pet bedding, floors, and even travel crates, making it versatile for various accidents around the home or car. The light Meyer lemon scent is subtle and fades quickly, so it doesn’t leave an overpowering fragrance behind.

Application is simple with the spray format, allowing you to target problem areas directly. It dries reasonably fast, helping you get back to normal use without long wait times. Safety is a key benefit here—it's free from chlorine and harmful propellants, and it’s certified safe for use around pets and children, including having a seal of approval from the Carpet and Rug Institute, meaning it's gentle on carpets and colors.

Some users might find the 32-ounce bottle size a bit small if cleaning large areas frequently, and while it's effective on many surfaces, always test on delicate fabrics first to avoid any unexpected reactions. The product has high customer satisfaction, reflecting its reliable performance. This cleaner suits pet owners looking for a dependable, safe, and easy-to-use solution for strong odors and stains, especially if you want a product that’s safe for pets and children with minimal scent.