10 Best Pet Urine Odor Removers 2025 in the United States

Rocco & Roxie Extreme Stain & Odor Eliminator is a strong enzyme-based cleaner designed to tackle tough pet stains and odors, including urine, vomit, and feces. Its bio-enzymatic formula actively breaks down organic messes and ammonia crystals, which makes it particularly effective for deep cleaning and odor removal. This product works well on a wide range of surfaces like carpets, furniture, pet bedding, floors, and even travel crates, making it versatile for various accidents around the home or car. The light Meyer lemon scent is subtle and fades quickly, so it doesn’t leave an overpowering fragrance behind.

Application is simple with the spray format, allowing you to target problem areas directly. It dries reasonably fast, helping you get back to normal use without long wait times. Safety is a key benefit here—it's free from chlorine and harmful propellants, and it’s certified safe for use around pets and children, including having a seal of approval from the Carpet and Rug Institute, meaning it's gentle on carpets and colors.

Some users might find the 32-ounce bottle size a bit small if cleaning large areas frequently, and while it's effective on many surfaces, always test on delicate fabrics first to avoid any unexpected reactions. The product has high customer satisfaction, reflecting its reliable performance. This cleaner suits pet owners looking for a dependable, safe, and easy-to-use solution for strong odors and stains, especially if you want a product that’s safe for pets and children with minimal scent.

The ACTIVE Pet Odor and Stain Eliminator is a solid choice for pet owners looking to tackle urine odors and stains without just masking them. Its enzyme-based formula uses natural probiotics to break down odors from dog and cat urine, as well as other messes like vomit or feces. This makes it effective in truly eliminating smells rather than covering them up. The spray works well on a variety of indoor surfaces such as carpets, upholstery, hardwood floors, furniture, and even pet bedding, making it versatile for most household messes. It leaves behind a natural citrus scent, which many will find fresh and not overpowering.

The application is straightforward: spray on the stain, let it soak up to an hour, then blot or wipe dry. While the soaking time might be longer than some prefer, this helps the enzymes penetrate deeply for better cleaning. The formula is safe for use around pets and kids, which is an important consideration for families. One minor drawback is that it may require multiple applications and some gentle scrubbing for very stubborn or old stains.

This product successfully balances gentle, natural ingredients with effective cleaning power, making it a practical option for pet owners aiming to keep their home fresh and stain-free.

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is a robust option for pet owners looking to tackle stubborn stains and odors. One of its standout features is its enzyme-based formula, which effectively targets and breaks down ammonia crystals found in pet urine and other organic stains. This means it doesn’t just mask the smell but eliminates it at the source, making it particularly beneficial for heavy-duty cleaning in homes with multiple pets or frequent accidents.

Compatibility is another strength; this product can be used on various surfaces, including carpets, floors, furniture, and even clothing. The versatility makes it a great choice for pet owners who need a single solution for different messes throughout the house. Additionally, it boasts a gentle and safe formulation that is certified by the Carpet and Rug Institute, ensuring that it won’t harm your carpets or leave behind any harmful residue, which is a significant plus for homes with children and pets.

There are a few considerations to keep in mind. While the enzyme action is effective, it may require some time to fully break down tougher stains and odors, meaning that immediate results might not always be visible. As for the scent, while it is marketed as an 'original' scent, some users may find that it does not completely neutralize all odors, particularly older stains that have set in. Furthermore, for larger areas, the 32oz size might not suffice, so purchasing multiple bottles could be necessary for extensive cleaning tasks.