10 Best Pet Urine Removers 2026 in the United States

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is an enzyme-based cleaner designed to tackle tough pet-related stains and odors. One of its standout features is its enzyme-activated formula, which effectively breaks down organic matter like urine and vomit, ensuring that both the stain and the accompanying smell are completely eliminated. This makes it a great option for households with pets, as it can be used on a variety of surfaces, including carpets, floors, furniture, and more. It's certified safe for pets and children, meaning you can use it without worrying about harmful chemicals lingering in your home.

There are a few things to keep in mind. While the product has a good reputation for odor neutralization and stain removal, it may require multiple applications for particularly stubborn stains, which can be a bit time-consuming. Additionally, although it's designed for all surfaces, it's wise to pre-test on hidden areas to avoid any potential discoloration.

In terms of ease of use, the spray bottle design makes application straightforward, but users should follow the instructions carefully to achieve the best results. The drying time is generally quick, which is beneficial for busy pet owners. This product is particularly well-suited for pet owners dealing with accidents from dogs and cats, as well as those who want a safe, effective solution for cleaning up after their furry friends. Its performance and safety features make it a solid addition to your cleaning supplies, especially if you have multiple pets or older animals that might have occasional accidents.

The Rocco & Roxie Extreme Stain & Odor Eliminator is a strong, enzyme-based cleaner designed to handle tough pet messes like urine, vomit, and feces. It uses a bio-enzymatic formula combined with mineral odor neutralizers, which helps break down stains and odors deeply rather than just masking them. This makes it especially effective for stubborn smells and stains on carpets, floors, furniture, pet bedding, and even travel crates.

The product is safe for use around pets and children when used as directed, as it is chlorine-free and leaves no residue. It has earned a Seal of Approval from the Carpet and Rug Institute, which speaks to its gentle yet effective nature on various surfaces. The subtle lemon scent is a nice touch, fading quickly so it doesn’t overpower your home.

Users generally find it easy to apply, though drying time can vary depending on the surface and amount used, which is normal for enzyme cleaners. Some might find the price a bit higher than basic cleaners, but the high number of positive reviews and the manufacturer’s satisfaction guarantee add confidence. This product is ideal for pet owners looking for a reliable, safe solution to deep-clean and neutralize strong odors and stains without harsh chemicals.

Angry Orange Pet Odor Eliminator is a strong choice for pet owners dealing with tough odors and stains, especially from dog and cat urine. It stands out because it uses natural orange oil, providing a fresh citrus scent rather than a typical chemical smell, which many users find pleasant. While it does not explicitly mention an enzyme-based formula, it effectively targets odors and stains on hard and sealed surfaces like floors, making it practical for common pet mess areas.

The product is safe for homes with pets and children when used as directed, as it avoids harsh chemicals like parabens and sulfates. It comes in a large gallon size, which can be economical for heavy use, though the spray format may require some effort to handle due to its volume. Its ease of use is enhanced by its spray form, but usage instructions should be followed closely for safety.

This product suits pet owners who want a powerful, natural-smelling cleaner for strong pet odors and stains on floors and similar surfaces, offering good value and safety when used properly.