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10 Best Pet Urine Removers 2026 in the United States

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Our Top Picks

#1

Winner

Rocco & Roxie Supply Co. Stain & Strong Odor Eliminator, Enzyme Cleaner, Pet Odor Eliminator for Home - Carpet Stain Remover for Cats & Dog Pee - Urine Destroyer - Carpet Cleaner Spray, 1-Gallon

Rating
10.0
Chosen by1,461
Enzyme-Based Formula
Surface Compatibility
Odor Neutralization

Most important from
123783 reviews

Enzyme-Based Formula
The enzyme-based formula truly works against the science of smells, making it a powerful solution for any odor issue, not just pet-related ones.
Surface Compatibility
The product is safe for all types of materials and doesn't leave any harmful residue, which speaks volumes about its quality and safety.
Odor Neutralization
After trying countless other products, this was the only one that completely removed the smell of cat urine from my home. It's worth every penny!
Stain Removal Effectiveness
This cleaner honestly is a miracle worker! It completely eliminated the smell and stains from my cats' marking spots, and they haven't returned to those areas since.

The Rocco & Roxie Supply Co. Stain & Odor Eliminator is an enzyme-based cleaner designed to tackle tough pet-related stains and odors. One of its standout features is its enzyme-activated formula, which effectively breaks down organic matter like urine and vomit, ensuring that both the stain and the accompanying smell are completely eliminated. This makes it a great option for households with pets, as it can be used on a variety of surfaces, including carpets, floors, furniture, and more. It's certified safe for pets and children, meaning you can use it without worrying about harmful chemicals lingering in your home.

There are a few things to keep in mind. While the product has a good reputation for odor neutralization and stain removal, it may require multiple applications for particularly stubborn stains, which can be a bit time-consuming. Additionally, although it's designed for all surfaces, it's wise to pre-test on hidden areas to avoid any potential discoloration.

In terms of ease of use, the spray bottle design makes application straightforward, but users should follow the instructions carefully to achieve the best results. The drying time is generally quick, which is beneficial for busy pet owners. This product is particularly well-suited for pet owners dealing with accidents from dogs and cats, as well as those who want a safe, effective solution for cleaning up after their furry friends. Its performance and safety features make it a solid addition to your cleaning supplies, especially if you have multiple pets or older animals that might have occasional accidents.

Rating
10.0
Chosen by1,461
Enzyme-Based Formula
Surface Compatibility
Odor Neutralization

Most important from
123783 reviews

Enzyme-Based Formula
The enzyme-based formula truly works against the science of smells, making it a powerful solution for any odor issue, not just pet-related ones.
Surface Compatibility
The product is safe for all types of materials and doesn't leave any harmful residue, which speaks volumes about its quality and safety.
Odor Neutralization
After trying countless other products, this was the only one that completely removed the smell of cat urine from my home. It's worth every penny!
Stain Removal Effectiveness
This cleaner honestly is a miracle worker! It completely eliminated the smell and stains from my cats' marking spots, and they haven't returned to those areas since.
#2

Nature’s Miracle® Stain & Odor Remover, Tough on Dog Urine, Feces, Vomit, Drool and Other Organic Stains and Odors, 1 Gallon

Rating
8.2
Enzyme-Based Formula
Odor Neutralization
Stain Removal Effectiveness

Most important from
40433 reviews

Enzyme-Based Formula
Nature's Miracle is hands down the best enzymatic stain and odor remover for pet urine. Other brands left behind urine stains that kept reappearing.
Odor Neutralization
Smells great and works even better. My puppy kept having accidents in the same 2 spots, but after using this, no more messes!
Stain Removal Effectiveness
This is the best stain & odor remover. It's great for use on any dog fluids (urine, poop, vomit).

Nature’s Miracle® Stain & Odor Remover is a versatile cleaning solution designed to tackle tough organic stains and odors from dog urine, feces, vomit, and drool. The enzyme-based formula is effective in breaking down these stains and neutralizing odors, making it a strong choice for pet owners. The product can be used on various surfaces such as carpets, hard floors, furniture, and fabrics, adding to its convenience and versatility.

Its light citrus scent helps to mask unpleasant odors, although some users might prefer an unscented option. Safety is a key factor, and this product is safe for pets and children when used as directed, providing peace of mind for families. The liquid form makes it easy to apply, though some might find it a bit messy compared to sprays or wipes.

One of the strengths of this remover is its drying time, which is relatively quick, allowing cleaned areas to be used again soon after application. However, while it's effective on fresh stains, older or set-in stains might require multiple treatments to fully remove. Additionally, the 1-gallon size offers good value for money but can be cumbersome to handle for those with limited storage space. Nature’s Miracle® is a reliable and effective option for pet owners needing a robust cleaning solution for various organic stains and odors, though it may require some effort for tougher, older stains.

Rating
8.2
Enzyme-Based Formula
Odor Neutralization
Stain Removal Effectiveness

Most important from
40433 reviews

Enzyme-Based Formula
Nature's Miracle is hands down the best enzymatic stain and odor remover for pet urine. Other brands left behind urine stains that kept reappearing.
Odor Neutralization
Smells great and works even better. My puppy kept having accidents in the same 2 spots, but after using this, no more messes!
Stain Removal Effectiveness
This is the best stain & odor remover. It's great for use on any dog fluids (urine, poop, vomit).
#3

Angry Orange Pet Odor Eliminator for Dog and Cat Urine, Carpet Stains, and Strong Smells – Citrus Cleaner with Natural Orange Oil – 1 Gallon

Rating
8.2
Odor Neutralization
Ease of Use
Enzyme-Based Formula

Most important from
127423 reviews

Odor Neutralization
Effectively eliminates the toughest pet odors, especially cat urine, with no smell returning even after repeated use.
Ease of Use
A little product goes a long way; it’s surprisingly concentrated and requires only a few sprays to fully neutralize odors.
Enzyme-Based Formula
The natural orange oil base not only removes odors but also unexpectedly works as an effective deterrent for pests like ladybugs.

Angry Orange Pet Odor Eliminator is a strong choice for pet owners dealing with tough odors and stains, especially from dog and cat urine. It stands out because it uses natural orange oil, providing a fresh citrus scent rather than a typical chemical smell, which many users find pleasant. While it does not explicitly mention an enzyme-based formula, it effectively targets odors and stains on hard and sealed surfaces like floors, making it practical for common pet mess areas.

The product is safe for homes with pets and children when used as directed, as it avoids harsh chemicals like parabens and sulfates. It comes in a large gallon size, which can be economical for heavy use, though the spray format may require some effort to handle due to its volume. Its ease of use is enhanced by its spray form, but usage instructions should be followed closely for safety.

This product suits pet owners who want a powerful, natural-smelling cleaner for strong pet odors and stains on floors and similar surfaces, offering good value and safety when used properly.

Rating
8.2
Odor Neutralization
Ease of Use
Enzyme-Based Formula

Most important from
127423 reviews

Odor Neutralization
Effectively eliminates the toughest pet odors, especially cat urine, with no smell returning even after repeated use.
Ease of Use
A little product goes a long way; it’s surprisingly concentrated and requires only a few sprays to fully neutralize odors.
Enzyme-Based Formula
The natural orange oil base not only removes odors but also unexpectedly works as an effective deterrent for pests like ladybugs.

Buying Guide for the Best Pet Urine Removers

Choosing the right pet urine remover is essential for maintaining a clean and odor-free home. Pet urine can be challenging to clean because it can seep into carpets, upholstery, and other surfaces, leaving behind stains and odors. A good pet urine remover will not only clean the stain but also eliminate the odor, preventing your pet from marking the same spot again. Here are some key specifications to consider when selecting a pet urine remover.
Enzyme-Based FormulaAn enzyme-based formula is important because enzymes break down the proteins in urine, effectively removing both the stain and the odor. Enzyme cleaners are particularly effective for organic stains like urine, feces, and vomit. If you have pets that frequently have accidents, an enzyme-based cleaner is a must-have. Look for products that specifically mention enzymes on the label. For occasional accidents, a general cleaner might suffice, but for frequent issues, enzyme-based is the way to go.
Surface CompatibilitySurface compatibility refers to the types of surfaces the cleaner can be used on, such as carpets, hardwood floors, upholstery, and tiles. This is important because using the wrong cleaner on a surface can cause damage. Check the product label to ensure it is safe for the surfaces in your home. If you have a variety of surfaces, look for a versatile cleaner that works on multiple types. If you have mostly carpets, a carpet-specific cleaner might be more effective.
Odor NeutralizationOdor neutralization is crucial because it ensures that the smell of urine is completely eliminated, not just masked. This is important for preventing pets from returning to the same spot. Look for products that specifically mention odor neutralization or odor elimination. Some products use fragrances to mask odors, but these are less effective than those that neutralize odors at the source. If you have a sensitive nose or allergies, opt for a fragrance-free formula.
Stain Removal EffectivenessStain removal effectiveness is a measure of how well the product can remove visible stains. This is important for maintaining the appearance of your home. Products with strong stain removal capabilities will often mention 'deep cleaning' or 'professional strength' on the label. If you have light-colored carpets or upholstery, you may need a stronger stain remover. For darker surfaces, a standard cleaner might be sufficient.
Safety for Pets and ChildrenSafety for pets and children is a critical consideration because some cleaning products contain harsh chemicals that can be harmful if ingested or if they come into contact with skin. Look for products that are labeled as non-toxic, pet-safe, or child-safe. If you have young children or pets that are prone to licking surfaces, this is especially important. Always follow the usage instructions to ensure safety.
Ease of UseEase of use refers to how simple the product is to apply and how much effort is required to achieve results. This is important for convenience and efficiency. Some products come in spray bottles for easy application, while others may require mixing or additional tools. If you prefer a quick and easy solution, look for ready-to-use sprays. For more thorough cleaning, you might consider products that require a bit more effort but offer deeper cleaning.
Drying TimeDrying time is the amount of time it takes for the cleaned area to dry completely. This is important for preventing mold and mildew growth and for allowing you to use the area again quickly. Products with faster drying times are more convenient, especially for high-traffic areas. If you need to clean an area that your pet frequently uses, a quick-drying formula will be beneficial. For less frequently used areas, drying time may be less of a concern.

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