10 Best Spider Spray Indoor 2025 in the United States

The Ortho Home Defense Insect Killer for Indoor & Perimeter2 is a versatile pest control solution designed for use both indoors and outdoors. It effectively targets a wide range of pests, including ants, roaches, spiders, fleas, and more, thanks to its active ingredients, Bifenthrin and Zeta-Cypermethrin. One of the standout features is its long-lasting residual effect, providing up to 12 months of protection against ants, roaches, and spiders on non-porous surfaces, making it a good choice for lasting peace of mind.

The Comfort Wand is a user-friendly addition, allowing for easy and precise application without causing hand fatigue, which is especially helpful for larger areas or frequent use. Safety-wise, it's designed for confidence in use around kitchens, bathrooms, and other sensitive areas, although it’s always wise to follow all safety instructions provided. The spray is generally praised for its lack of strong, lingering odors, which can be a significant plus for indoor use.

However, like many chemical sprays, it’s important to handle it carefully and keep it away from children and pets. While effective against a range of insects, its performance against less common pests like scorpions and earwigs may vary. Additionally, its effectiveness on porous surfaces might not be as long-lasting. This spray is a comprehensive and user-friendly solution for common household pests, offering long-term protection and ease of use with its Comfort Wand. It’s ideal for those looking for an all-around pest control option without frequent reapplications.

The Mighty Mint 16 oz Peppermint Oil Insect & Pest Spray is a natural option for those dealing with spiders and other pests like ants. One of its major strengths is its use of powerful US peppermint oil, which is a natural ingredient known to be effective in repelling pests. This makes it a good choice for those seeking a non-chemical solution. The spray is extra concentrated, which helps in providing long-lasting protection. This means you won't need to reapply it frequently, saving you time and effort.

Users will also appreciate that it's safe to use as directed, minimizing concerns about harmful chemicals in the home, especially around pets and children. Its mint scent can be a refreshing change compared to the chemical odors associated with traditional insect sprays. However, if you're sensitive to strong smells, this might be a drawback. The product's ease of application and cleanup adds to its user-friendly appeal.

On the downside, as it comes in an aerosol form, it may not be as precise in application as other formats, potentially leading to wastage. Additionally, while effective against spiders and ants, its performance against other pests might not be as strong as specialized products. Mighty Mint is a safe, natural, and easy-to-use indoor spider spray, but its strong mint scent and aerosol delivery could be potential drawbacks for some users.

The Ortho Home Defense Max Indoor Insect Barrier is designed to tackle a wide range of household pests, including spiders, ants, roaches, fleas, and ticks. One of its standout features is the extended reach comfort wand, making application easy and reducing the need for bending or hand fatigue. The spray offers 12-month control on non-porous surfaces for ants, roaches, and spiders, which is a significant advantage for long-term prevention.

The product dries faster than previous Ortho formulas, which helps prevent stains and fumes, allowing people and pets to enter treated areas soon after application—this adds a layer of convenience and safety. Its active ingredients are efficient at killing a broad spectrum of insects quickly, making it a versatile choice for indoor pest control. On the downside, some users might find the spray has an odor, although it is generally considered mild and dissipates quickly.

Additionally, while it is labeled safe for indoor use, it's always wise to follow the safety instructions carefully to avoid any health risks. The product's ease of use is enhanced by the one-touch continuous stream, which eliminates the need for pumping. This insect barrier is best suited for individuals seeking a comprehensive indoor pest control solution with minimal hassle and long-lasting results.