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7 Best Vertical Mice 2025 in the United States

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Our Top Picks

#1

Winner

zelotes Wired Gaming Mouse with Joystick,10000DPI,11 Programmable Buttons,RGB,USB Optical Corded Vertical Ergonomic Mouse,Mice for Laptop,PC,Mac,Black

Rating
10.0
Chosen by1,352
Ergonomics
Size and Shape
DPI (Dots Per Inch)

Most important from
213 reviews

Ergonomics
The vertical shape elevates the hand just enough to reduce friction and discomfort during long work or gaming sessions.
Size and Shape
The compact size fits medium to small hands comfortably, with a shape that supports natural finger positioning better than some competitors.
DPI (Dots Per Inch)
The mouse features a high polling rate adjustable up to 1000 Hz, ensuring precise and responsive tracking.
Buttons and Customization
Buttons offer a satisfying, snappy click that avoids the mushy feel common in many ergonomic mice.
Connectivity
Despite being wired with a USB-A connection, the cable is durable and long enough to accommodate most setups.

The Zelotes Wired Gaming Mouse is a vertical ergonomic mouse designed to reduce wrist strain by supporting a natural hand position, which is beneficial for those who spend long hours at the computer. Its vertical shape helps minimize wrist twisting, potentially easing discomfort during extended use. It features a unique 5-direction joystick controlled by the thumb that can be customized to mimic keyboard commands, making it handy for gaming or productivity shortcuts. With 11 programmable buttons, users have plenty of options to personalize their setup, allowing quick access to multiple functions.

This mouse offers five DPI levels ranging from 1500 up to 10000, enabling adjustment of cursor speed to suit precise tasks or fast-paced gaming. It uses optical tracking for accurate movement and connects via a USB cable, eliminating concerns about battery life during use. Being wired means there is no need to recharge or replace batteries, which is convenient but limits freedom of movement compared to wireless models. The mouse is compatible with Windows versions and Mac OS; however, the customization software has limited functionality on Mac. It is compact, weighing about 5.8 ounces with dimensions that fit most hands comfortably, though exact fit may vary depending on hand size. RGB lighting adds a stylish gaming touch but serves only an aesthetic purpose.

One consideration is that the wired connection may restrict mobility and desk setup options. The joystick feature, while unique, might require an adjustment period and may not appeal to every user. Mac users may experience less flexibility in programming options. This mouse is well suited for gamers and office users seeking an ergonomic vertical mouse with extensive customization and adjustable sensitivity. It is a solid choice for those prioritizing wrist comfort and programmable controls, with the trade-offs of wired connectivity and software limitations on Mac.

Rating
10.0
Chosen by1,352
Ergonomics
Size and Shape
DPI (Dots Per Inch)

Most important from
213 reviews

Ergonomics
The vertical shape elevates the hand just enough to reduce friction and discomfort during long work or gaming sessions.
Size and Shape
The compact size fits medium to small hands comfortably, with a shape that supports natural finger positioning better than some competitors.
DPI (Dots Per Inch)
The mouse features a high polling rate adjustable up to 1000 Hz, ensuring precise and responsive tracking.
Buttons and Customization
Buttons offer a satisfying, snappy click that avoids the mushy feel common in many ergonomic mice.
Connectivity
Despite being wired with a USB-A connection, the cable is durable and long enough to accommodate most setups.
#2

ZLOT Wired Vertical Mouse,Ergonomic Design USB LED Optical Mouse with 6 Buttons and 4 Adjustable Sensitivity 1200/1600/2400/3200 DPI for Office, Gaming, PC, Computer,Laptop,Desktop,Black …

Rating
8.8
Ergonomics
Size and Shape
DPI (Dots Per Inch)

Most important from
495 reviews

Ergonomics
The ergonomic vertical design significantly reduces wrist tension, allowing prolonged use without discomfort and helping prevent issues like carpal tunnel syndrome.
Size and Shape
Some users find the forward button slightly hard to reach without adjusting hand position, suggesting minor design tweaks could improve thumb accessibility.
DPI (Dots Per Inch)
Smooth and responsive tracking provides precise cursor control, making it suitable for both office tasks and light gaming.
Buttons and Customization
Customizable buttons and DPI settings enhance productivity, with multiple presets and reprogrammable functions tailored to different workflows.
Connectivity
The wired USB connection offers stable performance without battery concerns, though it limits portability compared to wireless models.
Compatibility
Compatibility spans Windows, Mac, and Linux, though extra buttons only fully function on Windows, limiting some features for Mac users.

The ZLOT Wired Vertical Mouse stands out for its ergonomic vertical design, which helps reduce wrist strain by supporting your forearm in a more natural position, making it a good choice if you spend long hours at the computer. It offers four adjustable DPI settings (1200, 1600, 2400, and 3200), allowing smooth and precise cursor movement suitable for both office work and casual gaming. The six buttons include forward and back buttons that enhance web browsing on Windows, though these extra buttons don’t work on Mac OS.

Since it is a wired USB mouse, it provides a stable connection with no worries about battery life, but this also means it’s less portable than wireless options. Compatibility is broad, covering most Windows versions, Mac OS (with some button limitations), and Linux, making it versatile for many users. The size and shape are designed to fit comfortably in hand, but people with very small or very large hands might want to check the fit before buying.

While it is not a top-tier gaming mouse, its responsive optical tracking and multiple DPI levels make it suitable for light gaming. The mouse is generally well-regarded for its build quality and comes with technical support if needed. This mouse is a solid pick for users looking for ergonomic comfort combined with decent sensitivity and extra buttons for productivity rather than advanced gaming features.

Rating
8.8
Ergonomics
Size and Shape
DPI (Dots Per Inch)

Most important from
495 reviews

Ergonomics
The ergonomic vertical design significantly reduces wrist tension, allowing prolonged use without discomfort and helping prevent issues like carpal tunnel syndrome.
Size and Shape
Some users find the forward button slightly hard to reach without adjusting hand position, suggesting minor design tweaks could improve thumb accessibility.
DPI (Dots Per Inch)
Smooth and responsive tracking provides precise cursor control, making it suitable for both office tasks and light gaming.
Buttons and Customization
Customizable buttons and DPI settings enhance productivity, with multiple presets and reprogrammable functions tailored to different workflows.
Connectivity
The wired USB connection offers stable performance without battery concerns, though it limits portability compared to wireless models.
Compatibility
Compatibility spans Windows, Mac, and Linux, though extra buttons only fully function on Windows, limiting some features for Mac users.
#3

zelotes Optical Wireless Mouse,Rechargeable,2400DPI,Ergonomic Design Reduces Muscle Strain,USB Vertical Ergonomic Mouse,Cordless Portable Mouse for PC,Mac,Laptop

Rating
8.5
Ergonomics
Size and Shape
Buttons and Customization

Most important from
58 reviews

Ergonomics
The ergonomic design offers exceptional comfort, making it a standout choice over traditional mice.
Size and Shape
Its lightweight build feels sturdy and well-made, avoiding any cheap impression despite the low weight.
Buttons and Customization
Limited button customization keeps the functionality straightforward, ideal for office tasks rather than gaming.
Connectivity
Wireless connection via USB dongle is stable, though it requires keeping the receiver plugged in.
Battery Life
Battery life is impressive, and recharging is hassle-free, eliminating the need for constant battery replacements.

The zelotes Optical Wireless Mouse is designed to offer a comfortable experience for people who spend long hours using a computer. Its vertical shape helps keep your wrist in a natural position, which can reduce muscle strain and wrist pain. The mouse is made with a soft, skin-friendly surface that improves grip comfort. You can adjust the sensitivity with three DPI settings (1200, 1600, and 2400), so it works well for both everyday tasks and more precise movements. It connects wirelessly via a USB receiver, providing a stable connection without the need for Bluetooth, although this requires keeping the USB dongle plugged in.

The built-in rechargeable battery is a convenient feature, eliminating the hassle of constantly buying new batteries, though it does require remembering to charge it. Compatibility is broad, covering Windows (from Win7 to Win11) and Mac OS, making it versatile for most users. The mouse doesn’t have many customizable buttons beyond the DPI switch, which might be a drawback if you want more control or shortcuts. Its compact size makes it portable but might feel small for users with larger hands.

This mouse represents a solid choice if you want an ergonomic vertical design with basic wireless functionality and good comfort. It is especially suitable for office work and general computer use rather than gaming or heavy customization.

Rating
8.5
Ergonomics
Size and Shape
Buttons and Customization

Most important from
58 reviews

Ergonomics
The ergonomic design offers exceptional comfort, making it a standout choice over traditional mice.
Size and Shape
Its lightweight build feels sturdy and well-made, avoiding any cheap impression despite the low weight.
Buttons and Customization
Limited button customization keeps the functionality straightforward, ideal for office tasks rather than gaming.
Connectivity
Wireless connection via USB dongle is stable, though it requires keeping the receiver plugged in.
Battery Life
Battery life is impressive, and recharging is hassle-free, eliminating the need for constant battery replacements.

Buying Guide for the Best Vertical Mice

Choosing the right vertical mouse can significantly improve your comfort and productivity, especially if you spend long hours working on a computer. Vertical mice are designed to reduce strain on your wrist and forearm by promoting a more natural hand position. When selecting a vertical mouse, it's important to consider several key specifications to ensure you get the best fit for your needs.
ErgonomicsErgonomics refers to how well the mouse fits your hand and supports a natural posture. This is crucial because a well-designed ergonomic mouse can help prevent repetitive strain injuries and reduce discomfort. Look for a mouse that feels comfortable in your hand and allows your wrist to remain in a neutral position. If possible, try out different models to see which one feels the most natural and supportive for your hand size and shape.
Size and ShapeThe size and shape of a vertical mouse are important because they determine how well the mouse fits your hand. A mouse that is too large or too small can cause discomfort and reduce the effectiveness of the ergonomic design. Vertical mice come in various sizes, so consider the dimensions of your hand when choosing one. If you have smaller hands, look for a compact model, while those with larger hands may need a bigger mouse to ensure a comfortable grip.
DPI (Dots Per Inch)DPI measures the sensitivity of the mouse, indicating how much the cursor moves on the screen in response to your movements. Higher DPI settings allow for faster cursor movement, which can be useful for tasks that require precision, such as graphic design or gaming. Most vertical mice offer adjustable DPI settings, so you can choose the level of sensitivity that best suits your needs. If you perform tasks that require fine control, look for a mouse with a higher DPI range.
Buttons and CustomizationThe number and placement of buttons on a vertical mouse can affect your productivity and ease of use. Additional buttons can provide shortcuts for common tasks, such as navigating web pages or executing commands in software applications. Some vertical mice allow you to customize button functions to suit your workflow. Consider how many buttons you need and whether you prefer a mouse with customizable options to enhance your efficiency.
ConnectivityVertical mice can be either wired or wireless, and the choice between the two depends on your preferences and work environment. Wired mice offer a stable connection and do not require battery changes, making them ideal for stationary setups. Wireless mice provide more freedom of movement and reduce cable clutter, which can be beneficial for a clean and organized workspace. Consider your work habits and choose the connectivity option that best fits your needs.
Battery LifeIf you opt for a wireless vertical mouse, battery life becomes an important consideration. A mouse with a long battery life reduces the frequency of recharging or replacing batteries, ensuring uninterrupted use. Some wireless mice come with rechargeable batteries, while others use disposable ones. Think about how often you use the mouse and choose a model with a battery life that matches your usage patterns to avoid frequent interruptions.
CompatibilityEnsure that the vertical mouse you choose is compatible with your operating system and any specific software you use. Most mice are designed to work with common operating systems like Windows, macOS, and Linux, but it's always good to double-check. Additionally, some mice come with software that allows for advanced customization and settings adjustments, so make sure the mouse you select supports the features you need for your work or personal use.

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