10 Best Vertical Mice 2025 in the United States

The J-Tech Digital Wired Ergonomic Vertical USB Mouse is designed with a strong focus on ergonomics, featuring a 'handshake' design that aims to reduce strain on the arm, wrist, and hand, making it a good choice for individuals suffering from carpal tunnel syndrome. Its size and shape appear to be user-friendly, with additional thumb buttons for convenience, although the bulk might not suit everyone.

The mouse offers adjustable DPI settings (600/1000/1600), catering to different sensitivity preferences, which is useful for various tasks from casual browsing to precise work. While the buttons can be customized using third-party software, this might not be ideal for users expecting built-in customization software. Connectivity is via USB, ensuring stable and responsive performance, but it does limit mobility compared to wireless options. The product features a removable palm rest, adding to its ergonomic appeal.

Battery life is not directly applicable as it is a wired model, but it claims to have a rechargeable lithium battery, which is an interesting specification. The mouse is compatible with most non-metallic surfaces, enhancing its usability across different environments. Its relatively heavier weight (9.6 ounces) and larger dimensions (5 x 4.5 x 4 inches) might not be suitable for users with smaller hands or those who prefer lighter mice. This mouse is particularly beneficial for individuals seeking ergonomic relief and those who do not mind the wired connection for stable performance.

The Zelotes Wired Gaming Mouse is a vertical ergonomic mouse designed to reduce wrist strain by supporting a natural hand position, which is beneficial for those who spend long hours at the computer. Its vertical shape helps minimize wrist twisting, potentially easing discomfort during extended use. It features a unique 5-direction joystick controlled by the thumb that can be customized to mimic keyboard commands, making it handy for gaming or productivity shortcuts. With 11 programmable buttons, users have plenty of options to personalize their setup, allowing quick access to multiple functions.

This mouse offers five DPI levels ranging from 1500 up to 10000, enabling adjustment of cursor speed to suit precise tasks or fast-paced gaming. It uses optical tracking for accurate movement and connects via a USB cable, eliminating concerns about battery life during use. Being wired means there is no need to recharge or replace batteries, which is convenient but limits freedom of movement compared to wireless models. The mouse is compatible with Windows versions and Mac OS; however, the customization software has limited functionality on Mac. It is compact, weighing about 5.8 ounces with dimensions that fit most hands comfortably, though exact fit may vary depending on hand size. RGB lighting adds a stylish gaming touch but serves only an aesthetic purpose.

One consideration is that the wired connection may restrict mobility and desk setup options. The joystick feature, while unique, might require an adjustment period and may not appeal to every user. Mac users may experience less flexibility in programming options. This mouse is well suited for gamers and office users seeking an ergonomic vertical mouse with extensive customization and adjustable sensitivity. It is a solid choice for those prioritizing wrist comfort and programmable controls, with the trade-offs of wired connectivity and software limitations on Mac.

The ZLOT Vertical Gaming Mouse is designed with ergonomics in mind, featuring a vertical shape that supports your forearm and helps reduce wrist strain, which can be a big relief if you experience discomfort with traditional mice. Its size seems compact and suitable for most hands, though the dimensions suggest it’s quite slim. For sensitivity, it offers up to 10,000 DPI with 5 adjustable levels, allowing good precision whether you're gaming or working.

The mouse stands out with 11 programmable buttons, providing customization options for gamers who want quick access to commands. It has onboard memory to save your settings, which is handy if you switch computers. The connectivity is wired via USB, ensuring a stable 1000 Hz polling rate with no lag, but it means you’ll need to be near your PC and deal with the cable. It doesn’t rely on batteries, so battery life isn’t a concern here.

Compatibility covers a wide range of Windows versions and Linux, but there is no explicit mention of Mac support. The RGB lighting adds a nice visual touch without affecting performance. The product’s relatively low weight and slim profile might feel less substantial for some users used to heavier gaming mice. If you want an ergonomic vertical mouse with strong customization and precise tracking for gaming or long computer sessions, this ZLOT model is a solid choice, especially if you prefer wired devices. However, if you need wireless freedom or Mac compatibility, this might not be the best fit.