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10 Best Enzyme Pet Urine Remover 2025 in the United States

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Our Top Picks

#1

Winner

Nature’s Miracle Advanced Stain And Odor Eliminator for Dogs, Fresh Scent, Severe Mess Enzymatic Formula For Tough Pet Messes, 1 Gallon

Rating
10.0
Chosen by1,109
Enzyme Concentration
Scent
Drying Time

Most important from
3339 reviews

Enzyme Concentration
Effectively eliminates urine stains and odors, outperforming previous formulas.
Scent
The scent is noticeable but not overpowering, helping to mask unpleasant smells during cleaning.
Drying Time
A fast-acting formula that leaves surfaces ready to use quickly after application.

Nature’s Miracle Advanced Stain and Odor Eliminator is designed to tackle severe pet messes using an enzymatic formula that breaks down organic stains and odors effectively. It discourages pets from re-soiling the cleaned areas by fully removing odors, providing a lasting solution. The product works on a variety of surfaces including carpets, hard floors, furniture, and clothing, making it versatile for common household needs.

It features a light fresh scent that helps mask unpleasant smells during cleaning without being overpowering. The fast-drying formula allows the area to be ready for use again quickly. Application is straightforward as a liquid spray, suitable for dog owners dealing with strong, stubborn stains and odors across multiple surfaces, especially if a quick drying time and fresh scent are desired.

Rating
10.0
Chosen by1,109
Enzyme Concentration
Scent
Drying Time

Most important from
3339 reviews

Enzyme Concentration
Effectively eliminates urine stains and odors, outperforming previous formulas.
Scent
The scent is noticeable but not overpowering, helping to mask unpleasant smells during cleaning.
Drying Time
A fast-acting formula that leaves surfaces ready to use quickly after application.
#2

Pet Odor and Stain Eliminator - 32 oz ACTIVE Enzyme Cleaner for Dog & Cat Urine, Stain Remover Spray for Carpet, Upholstery, Hardwood, Spot Cleaning, Deodorizer for Dogs Cats Pets - Natural Citrus Oil

Rating
7.6
Enzyme Concentration
Surface Compatibility
Scent

Most important from
1871 reviews

Enzyme Concentration
The active enzyme formula truly eliminates odors rather than masking them, working reliably on carpets, hardwood floors, and upholstery.
Surface Compatibility
The active enzyme formula truly eliminates odors rather than masking them, working reliably on carpets, hardwood floors, and upholstery.
Scent
The natural citrus oil scent is refreshing without being overpowering, leaving homes smelling clean and fresh.
Eco-Friendliness
This stain remover has become a household essential for tackling pet and kid stains alike, praised for its toxin-free formula and pleasant citrus scent.

The Pet Odor and Stain Eliminator by ACTIVE is a versatile enzyme cleaner designed to tackle pet messes like urine, poop, and vomit. One of its standout features is the high enzyme concentration, which helps in effectively breaking down and removing odors and stains rather than just masking them. This makes it a powerful choice for dealing with tough, set-in stains on various surfaces, including carpets, upholstery, hardwood floors, and even mattresses. The addition of natural probiotics further enhances its cleaning efficacy, making it a comprehensive solution for pet owners.

The citrus oil scent is a pleasant touch, leaving behind a fresh smell after cleaning, which can be a nice change from harsher chemical odors some other products have. Application is straightforward with its spray bottle, allowing for easy spot cleaning without needing additional tools. However, the drying time isn't specified, which might be a concern for users needing quick turnaround times.

The product is eco-friendly and made with natural ingredients, which is great for homes with pets and kids, but some users might find the citrus scent a bit too strong. Additionally, being in liquid form, it requires careful storage to avoid spills. This product is particularly beneficial for pet owners who need a reliable and effective cleaner for a variety of surfaces and who prefer eco-friendly cleaning solutions with a pleasant scent.

Rating
7.6
Enzyme Concentration
Surface Compatibility
Scent

Most important from
1871 reviews

Enzyme Concentration
The active enzyme formula truly eliminates odors rather than masking them, working reliably on carpets, hardwood floors, and upholstery.
Surface Compatibility
The active enzyme formula truly eliminates odors rather than masking them, working reliably on carpets, hardwood floors, and upholstery.
Scent
The natural citrus oil scent is refreshing without being overpowering, leaving homes smelling clean and fresh.
Eco-Friendliness
This stain remover has become a household essential for tackling pet and kid stains alike, praised for its toxin-free formula and pleasant citrus scent.
#3

Eco Strong Pet Stain and Odor Remover - Cat Urine Enzyme Cleaner Destroyer, Urine Destroyer for Dogs, Pet Urine Enzyme Cleaner - 128 Oz

Rating
7.6
Scent

Most important from
1047 reviews

Scent
The citrus scent is pleasant and not overpowering, offering a refreshing alternative to chemical-like odors.

The Eco Strong Pet Stain and Odor Remover is designed specifically for tackling pet urine and other organic stains using a natural bio-enzymatic formula. This ensures the product does more than just mask odors; it breaks down the proteins causing the stains and smells, making it highly effective for both cat and dog urine. One of its strengths is its versatility, as it can be used on a variety of surfaces including carpets, furniture, hardwood, and even in litter boxes.

The product is also made to be eco-friendly, being non-toxic, non-corrosive, and non-flammable, which makes it safe to use around pets and children. The scent is citrus, which many find pleasant and refreshing. However, some users might prefer an unscented option. The application method is straightforward, requiring users to spray the solution on the affected area and let it dry, which might be a bit longer compared to some other products.

This large 128 oz bottle means it’s cost-effective and will last a considerable time, though its size may make it less convenient to handle. Given its strong cleaning ability, eco-friendliness, and versatility, this product is particularly suitable for households with multiple pets that frequently deal with various accidents and stains.

Rating
7.6
Scent

Most important from
1047 reviews

Scent
The citrus scent is pleasant and not overpowering, offering a refreshing alternative to chemical-like odors.

Buying Guide for the Best Enzyme Pet Urine Remover

Choosing the right enzyme pet urine remover can make a significant difference in maintaining a clean and odor-free home. Enzyme cleaners are specifically designed to break down the proteins in pet urine, eliminating both the stain and the odor. When selecting an enzyme pet urine remover, it's important to consider several key specifications to ensure you get the best product for your needs.
Enzyme ConcentrationEnzyme concentration refers to the amount of active enzymes present in the cleaner. This is important because higher concentrations of enzymes are generally more effective at breaking down urine proteins and removing stains and odors. Products with higher enzyme concentrations are typically more powerful and work faster, making them ideal for severe or old stains. For regular maintenance or minor accidents, a product with a moderate enzyme concentration may suffice.
Surface CompatibilitySurface compatibility indicates which types of surfaces the enzyme cleaner can be safely used on. This is crucial because using the wrong cleaner on certain surfaces can cause damage. Enzyme cleaners can be formulated for use on carpets, upholstery, hardwood floors, tile, and more. To choose the right one, consider where your pet has accidents most frequently and ensure the product is safe for those surfaces.
ScentThe scent of the enzyme cleaner can affect your overall satisfaction with the product. Some enzyme cleaners have a strong fragrance to mask odors, while others are unscented or have a mild scent. If you or your pet are sensitive to strong smells, you might prefer an unscented or lightly scented product. On the other hand, if you want to ensure your home smells fresh after cleaning, a product with a pleasant fragrance might be more suitable.
Application MethodThe application method refers to how the enzyme cleaner is applied to the affected area. Common methods include spray bottles, pour bottles, and foam applicators. The right choice depends on your preference and the size of the area you need to treat. Spray bottles are convenient for small spots and quick clean-ups, while pour bottles might be better for larger stains. Foam applicators can provide more controlled application and deeper penetration into carpets and upholstery.
Drying TimeDrying time is the amount of time it takes for the treated area to dry after applying the enzyme cleaner. This is important because a quicker drying time means you can use the area sooner and reduces the risk of mold or mildew growth. If you need to clean up quickly and have the area ready for use, look for products with a shorter drying time. However, some products with longer drying times may offer deeper cleaning benefits.
Eco-FriendlinessEco-friendliness refers to how environmentally friendly the enzyme cleaner is. This can include factors like biodegradable ingredients, non-toxic formulations, and recyclable packaging. If you are environmentally conscious, you may want to choose a product that is labeled as eco-friendly. These products are generally safer for your pets, your family, and the planet.

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